Glomerular Basement Membrane (GBM) Antibody IFA Test
Short Name: GBM Antibody IFA Test
Also known as: GBM Antibody Test, Goodpasture Syndrome Test, Anti-GBM Antibody Test
Glomerular Basement Membrane (GBM) Antibody IFA Test test available at DNA Labs India for ₹1,697. Uses Immunofluorescence Assay on Serum samples. Results in Same day report delivery as per input.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The primary purpose of the GBM Antibody IFA Test is to aid in the diagnosis of Goodpasture syndrome by detecting the presence of anti-GBM antibodies in the blood. This test is essential for evaluating patients with symptoms of renal failure, such as dark urine or swelling, or pulmonary issues like hemoptysis. It helps differentiate Goodpasture syndrome from other kidney or lung disorders, guiding appropriate treatment strategies to prevent organ damage. Additionally, it may be used to monitor disease activity in diagnosed patients.
- Test Code
- 667
- Price
- ₹1,697
- Sample Type
- Serum
- Result Time
- Same day report delivery as per input.
- Fasting Required
- Yes (8 hours)
- Method
- Immunofluorescence Assay
Sample Collection
Overnight fasting for 8-10 hours is preferred to ensure accurate results. Inform your healthcare provider about any medications or supplements you are taking.
Method: Venipuncture
Laboratory Analysis
A phlebotomist will collect a blood sample from a vein in your arm using standard venipuncture procedure. The process is quick and minimally invasive.
Report Delivery
Apply pressure to the puncture site with a cotton ball to prevent bruising. You can resume normal activities immediately, but avoid strenuous exercise for a few hours.
Timeline: Same day report delivery as per input.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of the GBM Antibody IFA Test is to aid in the diagnosis of Goodpasture syndrome by detecting the presence of anti-GBM antibodies in the blood. This test is essential for evaluating patients with symptoms of renal failure, such as dark urine or swelling, or pulmonary issues like hemoptysis. It helps differentiate Goodpasture syndrome from other kidney or lung disorders, guiding appropriate treatment strategies to prevent organ damage. Additionally, it may be used to monitor disease activity in diagnosed patients.
How to Prepare
- Overnight fasting for 8-10 hours before sample collection.
- Sample should be collected in a 2 mL SST tube, with a minimum of 1 mL serum.
- Ship refrigerated or frozen to maintain sample integrity.
- Label the sample correctly with patient details and test information.
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"Early diagnosis of Goodpasture syndrome through GBM Antibody IFA Test is critical to prevent irreversible kidney and lung damage. This test helps in timely intervention and management."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume (<1 mL serum).
- Hemolyzed, lipemic, or contaminated samples.
- Improperly labeled or stored samples beyond stability period.
- Sample collected in incorrect container (not SST).
Understanding Your Results
Negative
No detectable GBM antibodies. This makes Goodpasture syndrome less likely, but other kidney or lung conditions may still be present. Clinical correlation is advised.
Positive
GBM antibodies detected. This strongly suggests Goodpasture syndrome or anti-GBM disease. Immediate medical consultation is recommended for further evaluation and treatment initiation to prevent organ damage.
Consult a doctor immediately if you experience symptoms like coughing up blood, shortness of breath, swelling, or dark urine. Also, consult if the test result is positive or if you have concerns about kidney or lung health. Early intervention can prevent serious complications.
Limitations
- ⚠The test is not definitive alone; clinical correlation and additional tests are required for diagnosis.
- ⚠False positives can occur in some autoimmune conditions or infections.
- ⚠False negatives may happen if antibody levels are low or in early disease stages.
- ⚠It does not differentiate between active and past disease; clinical assessment is necessary.
Risks & Considerations
- ●Minor pain or bruising at the blood draw site.
- ●Rare risk of infection or hematoma.
- ●Potential for anxiety related to test results.
Interfering Factors
- ●Hemolyzed or lipemic blood samples may affect test accuracy.
- ●Recent blood transfusions or plasmapheresis could interfere with results.
- ●Certain medications that affect the immune system may alter antibody levels.
- ●Sample improper handling or storage beyond stability period.
Compare With Similar Tests
| Test | Glomerular Basement Membrane (GBM) Antibody IFA Test | Urinalysis | Serum Creatinine Test | Kidney Biopsy | Lung Function Tests |
|---|---|---|---|---|---|
| Comparison | Glomerular Basement Membrane (GBM) Antibody IFA Test |
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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