Hains Mycobacterium Tuberculosis First Line Drug Resistance Profile Test
Short Name: HAINS MTB First Line Drug Resistance Profile
Also known as: HAINS Mycobacterium Tuberculosis Drug Resistance Test, HAINS MTB Drug Resistance Profile
Hains Mycobacterium Tuberculosis First Line Drug Resistance Profile Test test available at DNA Labs India for ₹3,000. Uses PCR, Line probe assay on Sputum / Bronchoalveolar Lavage / Pleural aspirates / CSF / Body fluid OR Cultured growth on appropriate media samples. Results in Sample collection: Tue / Fri by 11 am; Report available: Thu / Mon. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Kothari Ramesh Shantilal
Consultant Microbiologist · Reg: 27670
Last reviewed: September 7, 2026
Overview
To diagnose drug-resistant tuberculosis by detecting mutations in genes responsible for resistance to Rifampicin and Isoniazid, first-line TB drugs.
- Test Code
- 681
- Price
- ₹3,000
- Sample Type
- Sputum / Bronchoalveolar Lavage / Pleural aspirates / CSF / Body fluid OR Cultured growth on appropriate media
- Result Time
- Sample collection: Tue / Fri by 11 am; Report available: Thu / Mon
- Fasting Required
- No
- Method
- PCR, Line probe assay
Sample Collection
No special preparation required. Ensure sample is collected as per instructions.
Method: Physician-assisted or home collection
Laboratory Analysis
Sample collected by healthcare professional; for sputum, deep cough into sterile container; other fluids via standard procedures.
Report Delivery
Seal container properly and ship refrigerated; do not freeze.
Timeline: Sample collection: Tue / Fri by 11 am; Report available: Thu / Mon
Patient Instructions
About This Test
Who Should Get This Test
To diagnose drug-resistant tuberculosis by detecting mutations in genes responsible for resistance to Rifampicin and Isoniazid, first-line TB drugs.
How to Prepare
- Submit 2 mL (minimum 1 mL) of sputum, bronchoalveolar lavage, pleural aspirates, CSF, or body fluid
- Alternatively, submit cultured growth on appropriate media in a sterile screw capped container
- Place container in a sealed plastic bag
- Ship refrigerated; do not freeze
- Use provided home collection service if available
Doctor's Notes
Reviewed by Dr Kothari Ramesh Shantilal — MBBS, MD (Microbiology) · Reg. No. 27670
"This test is critical for identifying drug-resistant TB strains, enabling targeted therapy and preventing transmission of resistant infections. Consult an infectious disease specialist for result interpretation and treatment planning."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume
- Improperly labeled or contaminated sample
- Sample not shipped refrigerated as instructed
- Frozen sample
Understanding Your Results
Mutation Detected
Strain is resistant to the respective drug; consider alternative treatment
No Mutation Detected
Strain is likely susceptible to the drug, but clinical correlation is recommended
Indeterminate
Repeat test or use additional diagnostics for confirmation
Consult an infectious disease specialist or pulmonologist immediately after receiving results, especially if resistance is detected, to adjust treatment regimen and prevent complications.
Limitations
- ⚠May not detect all genetic mutations causing resistance
- ⚠Positive result confirms resistance but negative result does not entirely rule out resistance
- ⚠Test performance depends on sample quality and bacterial load
- ⚠Not a substitute for clinical evaluation and culture testing
Risks & Considerations
- ●Minimal risk from sample collection, such as discomfort during sputum expectoration or fluid aspiration
- ●No significant risks associated with the test itself
Interfering Factors
- ●Sample contamination
- ●Improper storage or shipping conditions
- ●Low bacterial load in sample
- ●Prior antibiotic treatment affecting bacterial presence
Compare With Similar Tests
| Test | Hains Mycobacterium Tuberculosis First Line Drug Resistance Profile Test | GeneXpert MTB/RIF Test | Sputum Culture and Sensitivity | Tuberculin Skin Test | Chest X-ray |
|---|---|---|---|---|---|
| Comparison | Hains Mycobacterium Tuberculosis First Line Drug Resistance Profile Test |
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