Hains Mycobacterium Tuberculosis First & Second Line Drug Resistance Profile Test
Short Name: HAINS TB Resistance Test
Also known as: HAINS TB Drug Resistance Profile, Mycobacterium Tuberculosis Resistance Test, TB First & Second Line Resistance Test
Hains Mycobacterium Tuberculosis First & Second Line Drug Resistance Profile Test test available at DNA Labs India for ₹7,020. Uses PCR, Line Probe Assay on Sputum / bronchoalveolar lavages / bronchial aspirates / Cultured growth samples. Results in Reports typically available within 5-7 days from sample collection. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Kothari Ramesh Shantilal
Consultant Microbiologist · Reg: 27670
Last reviewed: September 7, 2026
Overview
This molecular assay is useful to elucidate the mutations responsible for resistance to first line drugs such as Rifampicin & Isoniazid and second line drugs such as Fluoroquinolones, Capreomycin, Viomycin, Amikacin and Kanamycin. It helps in guiding treatment decisions for drug-resistant tuberculosis.
- Test Code
- 682
- Price
- ₹7,020
- Sample Type
- Sputum / bronchoalveolar lavages / bronchial aspirates / Cultured growth
- Result Time
- Reports typically available within 5-7 days from sample collection
- Fasting Required
- No
- Method
- PCR, Line Probe Assay
Sample Collection
No special preparation required
Method: Sputum collection or bronchoalveolar lavage
Laboratory Analysis
Follow standard sputum collection procedures; ensure proper hygiene to avoid contamination
Report Delivery
Ship refrigerated, do not freeze
Timeline: Reports typically available within 5-7 days from sample collection
Patient Instructions
About This Test
Who Should Get This Test
This molecular assay is useful to elucidate the mutations responsible for resistance to first line drugs such as Rifampicin & Isoniazid and second line drugs such as Fluoroquinolones, Capreomycin, Viomycin, Amikacin and Kanamycin. It helps in guiding treatment decisions for drug-resistant tuberculosis.
How to Prepare
- Submit 3 mL (2 mL min.) of sputum, bronchoalveolar lavages, or bronchial aspirates
- Use a sterile screw capped container
- Place in a sealed plastic bag
- Ship refrigerated, do not freeze
Doctor's Notes
Reviewed by Dr Kothari Ramesh Shantilal — MBBS, MD (Microbiology) · Reg. No. 27670
"Early detection of drug resistance is crucial for effective TB treatment and preventing the spread of resistant strains. This test guides targeted therapy, improving patient outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume (< 2 mL)
- Contaminated or improperly stored sample
- Use of frozen samples
- Damaged container
Understanding Your Results
If detected, suggests resistance to Rifampicin; consult doctor for alternative first-line drugs.
If detected, indicates resistance to Isoniazid; treatment regimen may need adjustment.
If detected, resistance to Fluoroquinolones like Levofloxacin or Moxifloxacin; avoid these in therapy.
If detected, suggests resistance to Capreomycin, a second-line injectable drug.
If detected, indicates resistance to Viomycin; consider alternative second-line options.
If detected, resistance to Amikacin; other injectable drugs may be ineffective.
If detected, suggests resistance to Kanamycin; consult infectious disease specialist for regimen changes.
If symptoms persist, if resistance is detected, or if you have been diagnosed with tuberculosis, consult an infectious disease specialist for personalized treatment advice.
Limitations
- ⚠Detects only specific genetic mutations; not all resistance mechanisms may be identified
- ⚠Requires quality samples with adequate bacterial load
- ⚠Results should be correlated with clinical findings
Risks & Considerations
- ●Minimal risks from sample collection, such as throat irritation during sputum induction
- ●No significant risks associated with the test itself
Interfering Factors
- ●Sample contamination
- ●Improper sample collection or storage
- ●Presence of inhibitors in the sample
Compare With Similar Tests
| Test | Hains Mycobacterium Tuberculosis First & Second Line Drug Resistance Profile Test | |||||
|---|---|---|---|---|---|---|
| Comparison | Hains Mycobacterium Tuberculosis First & Second Line Drug Resistance Profile Test |
Frequently Asked Questions
What is the HAINS TB Drug Resistance Test?
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What samples are required?
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