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Helicobacter Pylori Bacterial Load Test

DNA Labs India | ISO 9001:2015 Certified

Helicobacter Pylori Bacterial Load Test

Short Name: H. pylori Bacterial Load

Also known as: H. pylori PCR, H. pylori bacterial load quantification

Helicobacter Pylori Bacterial Load Test test available at DNA Labs India for ₹6,000. Uses Real Time PCR on Gastric lavage, Biopsy samples. Results in Reports are available on the 3rd working day. Email reports within 36 hours, phone within 24 hours.. Free home collection in 300+ cities across India.

Molecular🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of the Helicobacter pylori bacterial load test is to detect the presence of H. pylori bacteria in the stomach and quantify its load. This aids in diagnosing active infection, monitoring treatment response, and assessing the risk of complications such as peptic ulcers or gastric cancer. The test is particularly useful for patients with persistent dyspepsia, refractory symptoms, or those who have failed previous eradication therapy.

Test Code
6152
CPT Code
87533
ICD Code
B96.81
Price
₹6,000
Sample Type
Gastric lavage, Biopsy
Result Time
Reports are available on the 3rd working day. Email reports within 36 hours, phone within 24 hours.
Fasting Required
No
Method
Real Time PCR
Step 1

Sample Collection

Inform your doctor about any medications you are taking, especially antibiotics, PPIs, or bismuth. You may be advised to stop these for 2 weeks before the test. Fasting is not required, but follow your doctor's instructions.

Method: Endoscopic biopsy or gastric lavage

Step 2

Laboratory Analysis

The sample is collected via endoscopy (biopsy) or gastric lavage. You may be given a sedative for endoscopy. The procedure is quick and generally painless.

Step 3

Report Delivery

After the procedure, you may experience mild throat discomfort or bloating. Resume normal activities as advised. Your doctor will discuss the results with you.

Timeline: Reports are available on the 3rd working day. Email reports within 36 hours, phone within 24 hours.

Patient Instructions

1
Before the Test:Inform your doctor about all medications. You may need to stop antibiotics, PPIs, or bismuth for 2 weeks before the test.
2
During the Test:The sample is collected via endoscopy or gastric lavage. You may receive a sedative. The procedure is quick.
3
After the Test:You can resume normal activities. Mild throat discomfort may occur. Follow your doctor's advice.

About This Test

Who Should Get This Test

The purpose of the Helicobacter pylori bacterial load test is to detect the presence of H. pylori bacteria in the stomach and quantify its load. This aids in diagnosing active infection, monitoring treatment response, and assessing the risk of complications such as peptic ulcers or gastric cancer. The test is particularly useful for patients with persistent dyspepsia, refractory symptoms, or those who have failed previous eradication therapy.

How to Prepare

  • Sign the consent document before sample collection.
  • Bring any relevant clinical history of the patient.
  • Ensure the sample is transported immediately to the laboratory.

Doctor's Notes

Reviewed by — MBBS, MD (Microbiology) · Reg. No. 27670

"Quantifying H. pylori bacterial load helps guide treatment decisions, especially in cases of persistent infection or suspected antibiotic resistance. PCR-based testing offers high sensitivity and specificity."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeGastric lavage, Biopsy
Sample VolumeAs per specimen
ContainerSterile container with transport medium
Collection MethodEndoscopic biopsy or gastric lavage

Sample Stability

Biopsy sample: Stable for 24 hours at 2-8°C
Gastric lavage: Stable for 24 hours at 2-8°C
Sample Rejection Criteria:
  • Insufficient sample volume
  • Sample not transported in appropriate transport medium
  • Sample received after prolonged delay (>48 hours)

Understanding Your Results

The H. pylori bacterial load test result is reported as detected or not detected, along with the bacterial load in copies/mL. A positive result indicates active infection, while a negative result suggests no current infection.
📊

Not detected

No H. pylori DNA found. Active infection unlikely.

📊

Detected (low load: <1000 copies/mL)

Presence of H. pylori. May indicate early infection or low bacterial density.

📊

Detected (moderate load: 1000-10,000 copies/mL)

Active infection with significant bacterial load. Treatment recommended.

📊

Detected (high load: >10,000 copies/mL)

High bacterial load. Increased risk of complications. Urgent treatment advised.

⚠️ When to Consult a Doctor:

Consult your doctor if you experience persistent abdominal pain, blood in stool or vomit, unexplained weight loss, or if you have been diagnosed with H. pylori and need follow-up testing.

Limitations

  • The test cannot differentiate between active and past infection if the patient has been treated recently.
  • Quantification may not correlate with disease severity.
  • Requires specialized laboratory equipment and trained personnel.

Risks & Considerations

  • Minimal risk of bleeding or infection at biopsy site
  • Sore throat after endoscopy
  • Reaction to sedative (rare)

Interfering Factors

  • Recent use of antibiotics, bismuth compounds, or proton pump inhibitors (PPIs) may reduce bacterial load and cause false negatives.
  • Improper sample collection or transport may degrade DNA.
  • Contamination during collection can lead to false positives.

Compare With Similar Tests

TestHelicobacter Pylori Bacterial Load TestUrea Breath TestStool Antigen TestSerology (Antibody Test)
ComparisonHelicobacter Pylori Bacterial Load Test

Frequently Asked Questions

What is the cost of the H. pylori bacterial load test?
The test costs INR 6000, which includes the test, consultation, and free home sample collection.
How is the sample collected?
The sample is collected via gastric lavage or endoscopic biopsy. Both methods are performed by trained professionals.
Do I need to fast before the test?
No, fasting is not required. However, you should inform your doctor about any medications you are taking.
How long does it take to get results?
Reports are available on the 3rd working day. Email reports are sent within 36 hours, and phone results within 24 hours.
Is home sample collection available?
Yes, we offer free home sample collection for online bookings across major cities in India.
What is the accuracy of this test?
Real-Time PCR is highly accurate with sensitivity and specificity above 95%.
Can I take antibiotics before the test?
No, antibiotics, PPIs, and bismuth should be stopped at least 2 weeks before the test to avoid false negatives.
What does a positive result mean?
A positive result indicates the presence of H. pylori DNA, suggesting an active infection that requires treatment.
What does a negative result mean?
A negative result means no H. pylori DNA was detected, indicating no current infection.
Is the test covered by insurance?
Currently, this test is not covered by insurance schemes. Please check with your provider for reimbursement options.
What is the difference between this test and a biopsy culture?
PCR detects bacterial DNA and quantifies load, while culture grows the bacteria. PCR is faster and more sensitive.
Can this test be done for children?
Yes, the test can be performed on children, but the sample collection method may vary. Consult your pediatrician.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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