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Helicobacter Pylori (RNA Detection) Qualitative Test

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Helicobacter Pylori (RNA Detection) Qualitative Test

Short Name: H. pylori RNA Qualitative

Also known as: H. pylori RNA PCR, Helicobacter pylori RNA detection

Helicobacter Pylori (RNA Detection) Qualitative Test test available at DNA Labs India for ₹6,000. Uses Real Time PCR on Gastric lavage, Biopsy samples. Results in Results are typically available within 3 working days after the sample reaches the laboratory. You will receive an email or WhatsApp notification once the report is ready.. Free home collection in 300+ cities across India.

Molecular🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of the H. pylori RNA Detection Qualitative Test is to accurately detect the presence of H. pylori bacteria in gastric samples, confirming active infection. This aids in diagnosing the cause of gastrointestinal symptoms, guiding appropriate antibiotic treatment, and monitoring the effectiveness of eradication therapy. Unlike antibody tests that may reflect past infection, RNA detection indicates current bacterial activity, making it a valuable tool in clinical management.

Test Code
6153
CPT Code
87533
ICD Code
B96.81
Price
₹6,000
Sample Type
Gastric lavage, Biopsy
Result Time
Results are typically available within 3 working days after the sample reaches the laboratory. You will receive an email or WhatsApp notification once the report is ready.
Fasting Required
No
Method
Real Time PCR
Step 1

Sample Collection

Inform your doctor about any medications you are taking, especially antibiotics, proton pump inhibitors, or bismuth compounds, as they may affect test results. You may need to stop these medications for a certain period before the test. Fasting is not required, but follow your doctor's instructions.

Method: Endoscopic biopsy or gastric lavage

Step 2

Laboratory Analysis

The sample is collected via endoscopy (biopsy) or gastric lavage by a trained healthcare professional. You may be given a sedative for endoscopy. The procedure is generally safe and takes about 15-20 minutes.

Step 3

Report Delivery

After the procedure, you may experience mild sore throat or bloating. You can resume normal activities unless advised otherwise. Your doctor will discuss the results and further management.

Timeline: Results are typically available within 3 working days after the sample reaches the laboratory. You will receive an email or WhatsApp notification once the report is ready.

Patient Instructions

1
Before the Test:Inform your doctor about all medications you are taking. You may need to stop antibiotics, bismuth, or proton pump inhibitors for at least 2 weeks before the test. Fasting is not required.
2
During the Test:The sample collection is done via endoscopy or gastric lavage. You will be given local anesthesia or sedation. The procedure is quick and usually painless.
3
After the Test:You may have a mild sore throat or bloating. Rest for a short while. Your doctor will explain the results and next steps.

About This Test

Who Should Get This Test

The purpose of the H. pylori RNA Detection Qualitative Test is to accurately detect the presence of H. pylori bacteria in gastric samples, confirming active infection. This aids in diagnosing the cause of gastrointestinal symptoms, guiding appropriate antibiotic treatment, and monitoring the effectiveness of eradication therapy. Unlike antibody tests that may reflect past infection, RNA detection indicates current bacterial activity, making it a valuable tool in clinical management.

How to Prepare

  • Sample must be collected in a sterile container with appropriate transport medium
  • Biopsy samples should be placed in RNA stabilization solution if available
  • Label the container with patient details and collection time
  • Transport to the laboratory immediately at 2-8°C

Doctor's Notes

Reviewed by — MBBS, MD (Microbiology) · Reg. No. 27670

"RNA-based detection offers high sensitivity and specificity for active H. pylori infection, aiding in targeted antibiotic therapy."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeGastric lavage, Biopsy
Sample VolumeAs required
ContainerSterile container with transport medium
Collection MethodEndoscopic biopsy or gastric lavage

Sample Stability

Gastric biopsy: 24 hours at 2-8°C
Gastric lavage: 24 hours at 2-8°C
For longer storage, freeze at -20°C or -70°C
Sample Rejection Criteria:
  • Sample not in proper transport medium
  • Sample leaked or contaminated
  • Insufficient quantity
  • Delay in transport beyond 24 hours without proper storage

Understanding Your Results

The H. pylori RNA Qualitative Test result is reported as 'Detected' or 'Not Detected'. A 'Detected' result indicates the presence of H. pylori RNA, suggesting active infection. A 'Not Detected' result suggests no evidence of H. pylori RNA in the sample, which may indicate absence of infection or low bacterial load.
📊

Detected

Active H. pylori infection present. Antibiotic therapy may be required. Consult your physician for treatment.

📊

Not Detected

No H. pylori RNA detected. Infection unlikely, but clinical correlation is advised.

⚠️ When to Consult a Doctor:

Consult your doctor if you experience persistent gastrointestinal symptoms such as abdominal pain, bloating, nausea, or unexplained weight loss. Early diagnosis and treatment of H. pylori infection can prevent complications like ulcers and gastric cancer.

Limitations

  • Qualitative test does not provide bacterial load quantification
  • May not distinguish between active and past infection if RNA persists
  • Requires invasive sample collection (biopsy/lavage)
  • False negatives possible if sample is not representative

Risks & Considerations

  • Minor bleeding at biopsy site
  • Sore throat
  • Reaction to sedation (rare)
  • Infection (very rare)

Interfering Factors

  • Recent use of antibiotics or proton pump inhibitors may reduce bacterial load
  • Improper sample collection or transport may affect RNA integrity
  • Contamination during biopsy procedure

Compare With Similar Tests

TestHelicobacter Pylori (RNA Detection) Qualitative TestH. pylori Stool AntigenH. pylori Urea Breath TestH. pylori Serology (IgG)
ComparisonHelicobacter Pylori (RNA Detection) Qualitative Test

Frequently Asked Questions

What is the cost of the H. pylori RNA Detection Qualitative Test?
The test costs INR 6000 at DNA Labs India, with free home sample collection included.
What sample is required for this test?
The test requires a gastric biopsy or gastric lavage sample, collected during endoscopy.
Do I need to fast before the test?
No, fasting is not required. However, you may need to stop certain medications as advised by your doctor.
How is the test performed?
The test uses Real-Time PCR to detect H. pylori RNA in the sample, providing a qualitative result.
When will I get the report?
Reports are available within 3 working days after the sample is received in the laboratory.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for this test in over 200 cities across India.
What does a 'Detected' result mean?
A 'Detected' result indicates the presence of H. pylori RNA, suggesting an active infection.
What does a 'Not Detected' result mean?
A 'Not Detected' result suggests no H. pylori RNA was found, indicating no active infection.
Can I take antibiotics before the test?
You should avoid antibiotics, bismuth, and proton pump inhibitors for at least 2 weeks before the test, as they may affect results.
Is this test better than a blood antibody test?
Yes, RNA detection is more accurate for active infection compared to antibody tests, which may reflect past exposure.
Are there any risks with the sample collection?
The procedure is generally safe. Minor risks include sore throat, bleeding, or reaction to sedation, but these are rare.
Is the test covered by insurance?
Insurance coverage varies. Please check with your insurance provider or our customer support for assistance.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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