Hi-C Sequencing Test
Also known as: Chromosome Conformation Capture Sequencing, 3C Sequencing, Hi-C
Hi-C Sequencing Test test available at DNA Labs India for ₹135,000. Uses Hi-C Sequencing, Chromatin Conformation Capture on Extracted DNA samples. Results in 6 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of Hi-C sequencing is to map the three-dimensional structure of the genome, identify chromatin interactions, and detect genetic mutations that contribute to various disorders. It helps in understanding the functional organization of the genome and diagnosing conditions linked to structural variations, such as chromosomal rearrangements and copy number variations.
- Test Code
- 3412
- Price
- ₹135,000
- Sample Type
- Extracted DNA
- Result Time
- 6 weeks
- Fasting Required
- No
- Method
- Hi-C Sequencing, Chromatin Conformation Capture
Sample Collection
No specific preparation required. Inform the lab of any medications or medical conditions.
Method: Home Collection or Walk-in
Laboratory Analysis
DNA sample will be collected via blood draw or other methods, taking approximately 15-30 minutes.
Report Delivery
Sample will be processed in the lab for sequencing. Resume normal activities immediately.
Timeline: 6 weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of Hi-C sequencing is to map the three-dimensional structure of the genome, identify chromatin interactions, and detect genetic mutations that contribute to various disorders. It helps in understanding the functional organization of the genome and diagnosing conditions linked to structural variations, such as chromosomal rearrangements and copy number variations.
How to Prepare
- Provide a DNA sample as instructed by the lab
- Ensure sample is labeled correctly with patient details
- Follow home collection guidelines if applicable
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Hi-C sequencing provides critical insights into chromosomal architecture, aiding in the diagnosis of complex genetic conditions and guiding personalized treatment."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed samples
- Insufficient sample volume
- Contaminated samples
Understanding Your Results
If results indicate potential genetic abnormalities, chromosomal rearrangements, or if symptoms persist or worsen, consult a geneticist or relevant specialist for personalized advice.
Limitations
- ⚠May not detect all point mutations
- ⚠Requires high-quality DNA
- ⚠Long turnaround time of 6 weeks
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or discomfort at the collection site
- ●No significant risks associated with the sequencing process itself
Interfering Factors
- ●Poor DNA quality
- ●Sample contamination
- ●Inadequate sample volume
Compare With Similar Tests
| Test | Hi-C Sequencing | Whole Genome Sequencing | Exome Sequencing | Chromosome Microarray Analysis | Fluorescence In Situ Hybridization (FISH) |
|---|---|---|---|---|---|
| Comparison | Hi-C Sequencing | Hi-C provides 3D genome structure and chromatin interactions, while WGS sequences the entire genome linearly for variant detection. | Hi-C includes non-coding regions and structural variations, whereas exome sequencing focuses on coding regions for mutations. | Hi-C offers higher resolution for chromatin interactions, while CMA detects copy number variations and loss of heterozygosity. | Hi-C provides genome-wide interaction data, while FISH targets specific loci for visualization. |
Frequently Asked Questions
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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