Human Immunodeficiency Virus 1 Genotyping & Drug Resistance Test
Short Name: HIV-1 Genotyping & Drug Resistance Test
Also known as: HIV-1 Genotyping Test, HIV Drug Resistance Test, HIV-1 RT-PCR Genotyping
Human Immunodeficiency Virus 1 Genotyping & Drug Resistance Test test available at DNA Labs India for ₹24,570. Uses Reverse Transcriptase PCR, DNA Sequencing on Plasma samples. Results in Results are reported on the 15th and 30th of every month. Online reports are accessible via the portal, email, or WhatsApp.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Kothari Ramesh Shantilal
Consultant Microbiologist · Reg: 27670
Last reviewed: September 7, 2026
Overview
The purpose of HIV-1 genotyping and drug resistance testing is to analyze the genetic structure of HIV-1 to identify mutations that may cause resistance to antiretroviral drugs. This information is used by healthcare providers to select the most effective treatment regimen, optimize therapy, and prevent treatment failure.
- Test Code
- 770
- Price
- ₹24,570
- Sample Type
- Plasma
- Result Time
- Results are reported on the 15th and 30th of every month. Online reports are accessible via the portal, email, or WhatsApp.
- Fasting Required
- No
- Method
- Reverse Transcriptase PCR, DNA Sequencing
Sample Collection
No special preparation required. Inform your healthcare provider about any medications or health conditions.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm using standard venipuncture technique. The process is quick and minimally invasive.
Report Delivery
Apply pressure to the puncture site to prevent bruising. Resume normal activities unless advised otherwise.
Timeline: Results are reported on the 15th and 30th of every month. Online reports are accessible via the portal, email, or WhatsApp.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of HIV-1 genotyping and drug resistance testing is to analyze the genetic structure of HIV-1 to identify mutations that may cause resistance to antiretroviral drugs. This information is used by healthcare providers to select the most effective treatment regimen, optimize therapy, and prevent treatment failure.
How to Prepare
- Collect 2 mL plasma in an EDTA (lavender top) tube
- Separate plasma within 6 hours of collection in a plastic transport vial
- Freeze the plasma sample immediately
- Ship the sample frozen to the laboratory
- Do not thaw the sample before testing
Doctor's Notes
Reviewed by Dr Kothari Ramesh Shantilal — MBBS, MD (Microbiology) · Reg. No. 27670
"This test helps in identifying mutations associated with resistance, guiding the initiation or change of antiretroviral treatment regimens for effective HIV management."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted samples
- Insufficient volume (less than 1 mL)
- Samples not separated or frozen within 6 hours
- Thawed samples during transit
- Improper labeling or documentation
Understanding Your Results
No mutations detected
The virus is likely susceptible to standard antiretroviral drugs. Treatment can proceed as per guidelines.
Mutations associated with resistance detected
The virus shows resistance to one or more antiretroviral agents. Treatment regimen may need modification based on the specific mutations and resistance patterns.
Inconclusive results
Repeat testing or additional clinical evaluation may be required. Consult your healthcare provider for guidance.
Consult your healthcare provider if you receive test results indicating drug resistance, if you experience symptoms of treatment failure (such as rising viral load or declining CD4 count), or before starting or changing antiretroviral therapy.
Limitations
- ⚠Test may not detect all possible resistance mutations
- ⚠Limited to known mutations in Reverse Transcriptase and Protease genes
- ⚠Results require interpretation in conjunction with clinical history and viral load
- ⚠Does not measure viral load or CD4 count
Risks & Considerations
- ●Minor bruising or pain at the puncture site
- ●Rare risk of infection or hematoma
- ●Slight dizziness during blood draw
Interfering Factors
- ●Hemolyzed or lipemic samples
- ●Improper sample storage or delayed processing
- ●Thawing of frozen samples
- ●Insufficient sample volume
- ●Contamination during collection
Compare With Similar Tests
| Test | Human Immunodeficiency Virus 1 Genotyping & Drug Resistance Test | HIV Viral Load Test | CD4 Count Test | HIV Antibody/Antigen Test | HIV RNA PCR Test |
|---|---|---|---|---|---|
| Comparison | Human Immunodeficiency Virus 1 Genotyping & Drug Resistance Test | Measures the quantity of HIV RNA in the blood, indicating treatment response, but does not detect drug resistance mutations. | Assesses immune system health by counting CD4 cells, but does not provide information on viral genetics or resistance. | Used for initial diagnosis by detecting antibodies or antigens, not for resistance profiling. | Detects HIV genetic material for diagnosis or monitoring, but genotyping specifically targets resistance mutations. |
Frequently Asked Questions
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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