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DNA Labs India

HLA - B22 (B*22) Test

DNA Labs India | ISO 9001:2015 Certified

HLA - B22 (B*22) Test

Short Name: HLA-B22 Test

Also known as: HLA B*22, Human Leukocyte Antigen B22

HLA - B22 (B*22) Test test available at DNA Labs India for ₹6,000. Uses Reverse SSOP - Luminex on Whole blood samples. Results in 10-12 days. Free home collection in 300+ cities across India.

Physician, Rheumatologist, Gastroenterologist🏠 Home Collection

🩺 Medically Reviewed By

Overview

To identify the presence of HLA-B22 allele for the diagnosis and risk assessment of associated autoimmune and inflammatory diseases.

Test Code
781
Price
₹6,000
Sample Type
Whole blood
Result Time
10-12 days
Fasting Required
No
Method
Reverse SSOP - Luminex
Step 1

Sample Collection

No fasting or special preparation is required. Inform your doctor about any medications you are taking.

Method: Venipuncture

Step 2

Laboratory Analysis

A healthcare professional will clean the area and insert a needle to draw blood from a vein in your arm.

Step 3

Report Delivery

You may experience slight bruising or discomfort at the puncture site. Apply pressure and avoid heavy lifting with that arm for a few hours.

Timeline: 10-12 days

Patient Instructions

1
Before the Test:No special preparation required.
2
During the Test:A blood sample will be collected.
3
After the Test:You can resume normal activities. Results will be available in 10-12 days.

About This Test

Who Should Get This Test

To identify the presence of HLA-B22 allele for the diagnosis and risk assessment of associated autoimmune and inflammatory diseases.

How to Prepare

  • Collect blood in specified EDTA or ACD tube
  • Label the tube correctly
  • Ship refrigerated; do not freeze
  • Ensure sample integrity during transport

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"This test is crucial for diagnosing autoimmune and inflammatory conditions. Early detection allows for timely intervention and better patient outcomes."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeWhole blood
Sample Volume4 mL or 6 mL
ContainerEDTA or ACD tube
Collection MethodVenipuncture

Sample Stability

Refrigerated (2-8°C)
Room Temperature
Frozen
Sample Rejection Criteria:
  • Sample volume less than minimum required
  • Hemolyzed or clotted sample
  • Incorrect tube type
  • Improper labeling or storage

Understanding Your Results

The HLA-B22 test result indicates whether the B*22 allele is present or absent. A positive result may increase the risk for associated conditions, but it does not confirm a diagnosis alone.
📊

Negative

HLA-B22 allele not detected. This reduces the likelihood of conditions strongly associated with this allele, but clinical evaluation is still necessary.

📊

Positive

HLA-B22 allele detected. This may indicate increased susceptibility to conditions like ankylosing spondylitis. Consult a specialist for further assessment and management.

⚠️ When to Consult a Doctor:

If you test positive for HLA-B22 or have persistent symptoms such as joint pain, skin changes, or digestive issues, consult a rheumatologist, dermatologist, or gastroenterologist.

Limitations

  • Test only detects HLA-B22; other alleles are not assessed
  • Results should be correlated with clinical symptoms and other tests
  • Cannot predict disease severity or progression

Risks & Considerations

  • Bruising at puncture site
  • Infection
  • Dizziness

Interfering Factors

  • Hemolyzed blood sample
  • Improper sample storage
  • Contamination during collection

Frequently Asked Questions

What is the HLA-B22 test?
The HLA-B22 test is a genetic test that detects the presence of the Human Leukocyte Antigen B22 allele, which is associated with certain autoimmune and inflammatory conditions.
Why is the HLA-B22 test recommended?
It is recommended to diagnose or assess risk for conditions like ankylosing spondylitis, psoriasis, and reactive arthritis, especially in individuals with relevant symptoms.
How is the HLA-B22 test performed?
A blood sample is collected and analyzed in a laboratory using methods like Reverse SSOP - Luminex to detect the HLA-B22 allele.
What does a positive HLA-B22 result mean?
A positive result means the HLA-B22 allele is present, indicating a higher risk for associated diseases, but it does not necessarily mean you have the condition.
What does a negative HLA-B22 result mean?
A negative result means the HLA-B22 allele is not detected, reducing the likelihood of strongly associated conditions, though other factors may be involved.
How much does the HLA-B22 test cost in India?
The cost is INR 6000 at DNA Labs India, which includes home sample collection across India.
Is the HLA-B22 test covered by insurance?
Insurance coverage varies. It is advisable to check with your insurance provider before undergoing the test.
How long does it take to get HLA-B22 test results?
Results are typically available in 10-12 days after sample collection.
Are there any risks associated with the HLA-B22 test?
The test involves a standard blood draw with minimal risks such as bruising or infection at the puncture site.
What conditions are linked to the HLA-B22 allele?
Conditions include ankylosing spondylitis, psoriasis, reactive arthritis, fixed drug eruptions, spondyloarthropathies, sarcoidosis, and inflammatory bowel disease.
How should I prepare for the HLA-B22 test?
No special preparation is required. However, inform your doctor about any medications or health conditions.
Where can I get the HLA-B22 test done?
You can book the test at DNA Labs India with free home sample collection in numerous cities across India. Visit our website or contact us for more information.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

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