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DNA Labs India

HLA Pre-Transplant Workup Non Sensitized Recipient Panel 1 Test

DNA Labs India | ISO 9001:2015 Certified

HLA Pre-Transplant Workup Non Sensitized Recipient Panel 1 Test

Short Name: HLA Pre-Transplant Workup Panel 1

Also known as: HLA Compatibility Test for Transplant, Non-Sensitized Recipient HLA Panel

HLA Pre-Transplant Workup Non Sensitized Recipient Panel 1 Test test available at DNA Labs India for ₹22,230. Uses Complement Dependent Cytotoxicity with DTT treatment, Reverse SSOP - Luminex, Luminex X-Map technology on Whole blood and serum samples. Results in 10-12 days. Free home collection in 300+ cities across India.

Nephrology Test🏠 Home Collection

Overview

Recipient: HLA DNA Typing for Kidney/Liver transplant (PCR Low resolution Luminex), HLA T & B cell lymphocyte cross match vs potential donor, HLA Panel Reactive IgG antibodies (PRA) Screen Luminex. This workup aims to assess HLA match/mismatch, detect allo-immunization status, and identify complement-fixing allo-antibodies to predict transplant compatibility.

Test Code
816
Price
₹22,230
Sample Type
Whole blood and serum
Result Time
10-12 days
Fasting Required
No
Method
Complement Dependent Cytotoxicity with DTT treatment, Reverse SSOP - Luminex, Luminex X-Map technology
Step 1

Sample Collection

Collect specimen preferably 48 hours after dialysis. Ensure doctor's prescription on letterhead with one photograph each of recipient and donor duly stamped. Consent form for HLA Typing for Solid organ transplant (Form 33) is mandatory.

Method: Venipuncture

Step 2

Laboratory Analysis

Standard venipuncture procedure under sterile conditions.

Step 3

Report Delivery

Label samples accurately and ship refrigerated. Do not freeze.

Timeline: 10-12 days

Patient Instructions

1
Before the Test:Ensure all documentation (consent form, prescription) is ready. Follow collection timing guidelines.
2
During the Test:Blood samples will be collected via standard procedures.
3
After the Test:Samples sent for analysis; reports available in 10-12 days.

About This Test

Who Should Get This Test

Recipient: HLA DNA Typing for Kidney/Liver transplant (PCR Low resolution Luminex), HLA T & B cell lymphocyte cross match vs potential donor, HLA Panel Reactive IgG antibodies (PRA) Screen Luminex. This workup aims to assess HLA match/mismatch, detect allo-immunization status, and identify complement-fixing allo-antibodies to predict transplant compatibility.

How to Prepare

  • Collect whole blood in specified tubes (ACD, EDTA) and serum in SST
  • Ensure specimens are collected 48 hours post-dialysis if applicable
  • Include signed consent form (Form 33) and doctor's prescription with photos
  • Ship samples refrigerated; avoid freezing

Doctor's Notes

"This test is crucial for evaluating donor-recipient compatibility in non-sensitized patients awaiting organ transplantation, particularly for kidneys or livers, to minimize rejection risks."

Test Parameters & Specifications

Sample TypeWhole blood and serum
Sample Volume6 mL whole blood in ACD tube, 3 mL serum in SST, 4 mL whole blood in EDTA tube
ContainerYellow Top (ACD) tube, SST (Serum Separator Tube), Lavender Top (EDTA) tube
Collection MethodVenipuncture

Sample Stability

Room Temperature
Refrigerator (2-8°C)
Frozen
Sample Rejection Criteria:
  • Missing consent form or prescription
  • Sample hemolysis
  • Incorrect storage
  • Inadequate sample volume

Understanding Your Results

Results indicate HLA compatibility and antibody status. Compatibility is determined by HLA match/mismatch, cross-match negativity, and low PRA levels. Positive cross-match or high PRA may require further evaluation.
📊

HLA Match

Higher compatibility reduces rejection risk

📊

Negative Cross-Match

No donor-specific antibodies detected, favorable for transplant

📊

Low PRA (<20%)

Lower sensitization, better transplant outcomes

📊

Positive Cross-Match or High PRA

Indicates sensitization; may require desensitization or alternate donor

⚠️ When to Consult a Doctor:

Consult your nephrologist or transplant specialist if results show incompatibility, high antibody levels, or if you have questions about transplant readiness.

Limitations

  • Results are qualitative and require specialist interpretation
  • Cannot predict all forms of rejection
  • Limited to non-sensitized recipients

Risks & Considerations

  • Minor bruising at puncture site
  • Rare infection risk
  • Minimal discomfort

Interfering Factors

  • Recent blood transfusions
  • Dialysis within 48 hours
  • Sample hemolysis
  • Improper sample storage

Frequently Asked Questions

What is the HLA Pre-Transplant Workup for non-sensitized recipients?
It is a diagnostic test assessing donor-recipient compatibility for organ transplants in patients without prior HLA exposure.
Who needs this test?
Patients awaiting organ transplants, such as kidney or liver, who are non-sensitized recipients.
How is the test performed?
Using methods like Luminex technology for HLA typing, cross-matching, and antibody screening.
What samples are required?
Whole blood in ACD and EDTA tubes, and serum in an SST tube.
Is fasting required?
No, but specimens should be collected 48 hours after dialysis if applicable.
What is the cost of this test?
INR 22230 at DNA Labs India, with free home collection available.
How long does it take to get results?
10-12 days after sample collection.
What documents are needed for the test?
Doctor's prescription with photos and a signed consent form (Form 33).
What does a positive cross-match mean?
It indicates donor-specific antibodies, suggesting higher rejection risk and possibly requiring further evaluation.
Can this test be done at home?
Yes, DNA Labs India offers free home sample collection in many cities across India.
Is the test covered by insurance?
Coverage varies; check with your insurance provider or scheme like PMJAY or CGHS.
What if I have a high PRA level?
High PRA indicates sensitization; consult your transplant specialist for desensitization options or alternate donors.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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