HNF1A Gene Diabetes mellitus, insulin-dependent type 20 NGS Genetic Test
Short Name: HNF1A Gene Diabetes Test
Also known as: MODY Type 3, HNF1A Diabetes, Maturity-Onset Diabetes of the Young Type 3
HNF1A Gene Diabetes mellitus, insulin-dependent type 20 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the HNF1A Gene Diabetes NGS Genetic Test is to accurately diagnose mutations in the HNF1A gene that cause Maturity-Onset Diabetes of the Young type 3 (MODY3), a rare form of diabetes. This test helps differentiate MODY3 from other types of diabetes, ensuring appropriate treatment and management. It is recommended for individuals with a family history of early-onset diabetes or symptoms suggestive of MODY, enabling personalized medical care and genetic counseling.
- Test Code
- 4667
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- NGS Technology
Sample Collection
No specific preparation is required. Ensure to provide accurate clinical and family history during genetic counseling.
Method: Venipuncture or FTA Card
Laboratory Analysis
A blood sample will be collected via venipuncture, or a drop of blood on an FTA card may be used. The procedure is quick and minimally invasive.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Resume normal activities immediately. Store the sample as instructed for stability.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the HNF1A Gene Diabetes NGS Genetic Test is to accurately diagnose mutations in the HNF1A gene that cause Maturity-Onset Diabetes of the Young type 3 (MODY3), a rare form of diabetes. This test helps differentiate MODY3 from other types of diabetes, ensuring appropriate treatment and management. It is recommended for individuals with a family history of early-onset diabetes or symptoms suggestive of MODY, enabling personalized medical care and genetic counseling.
How to Prepare
- Fast for 8-12 hours if required, though not mandatory for this test.
- Bring identification and referral documents.
- Inform the phlebotomist of any bleeding disorders or medications.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or insufficient sample volume
- Improperly labeled or contaminated samples
- Sample not stored correctly as per stability guidelines
Understanding Your Results
Positive for pathogenic mutation
Confirms diagnosis of MODY3 (HNF1A diabetes). Genetic counseling and tailored treatment are recommended.
Negative for mutations
No HNF1A gene mutations detected. Consider other genetic or non-genetic causes of diabetes.
Variant of uncertain significance (VUS)
Further testing or family studies may be needed for clarification. Clinical correlation is essential.
Consult a doctor if you have symptoms of diabetes, a family history of early-onset diabetes, or if you receive a positive or uncertain test result. Early consultation can guide appropriate management and genetic counseling.
Limitations
- ⚠This test only detects mutations in the HNF1A gene; other genetic causes of diabetes may not be identified.
- ⚠Results may require confirmation with additional clinical evaluation.
- ⚠Genetic testing cannot predict disease severity or onset timing with certainty.
Risks & Considerations
- ●Minimal risks such as slight pain, bruising, or infection at the puncture site
- ●No significant genetic risks from the test itself
Frequently Asked Questions
What is the HNF1A Gene Diabetes NGS Genetic Test?
Who should take this test?
What is the cost of the test?
Is home sample collection available?
How long does it take to get results?
What sample type is required?
Is fasting required before the test?
What does a positive result mean?
Can this test diagnose all types of diabetes?
Is genetic counseling included?
What are the risks of the test?
How accurate is the NGS technology?
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₹20,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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