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HS6ST1 Gene Hypogonadotropic hypogonadism type 15 with or without anosmia NGS Genetic Test

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HS6ST1 Gene Hypogonadotropic hypogonadism type 15 with or without anosmia NGS Genetic Test

Short Name: HS6ST1 HH Type 15 NGS Test

Also known as: Hypogonadotropic hypogonadism type 15, HH15 with or without anosmia, HS6ST1-related hypogonadism

HS6ST1 Gene Hypogonadotropic hypogonadism type 15 with or without anosmia NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of this test is to identify pathogenic variants in the HS6ST1 gene to confirm a diagnosis of hypogonadotropic hypogonadism type 15 with or without anosmia, guide treatment decisions, and facilitate genetic counseling for affected individuals and their families.

Test Code
5442
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Genetic counseling session recommended. Provide clinical history and family pedigree.

Method: Venipuncture or FTA card spot

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or FTA card spot.

Step 3

Report Delivery

Sample sent to laboratory for NGS analysis. Report available in 3-4 weeks.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Genetic counseling and clinical evaluation.
2
During the Test:Sample collection and processing.
3
After the Test:Report generation and genetic counseling follow-up.

About This Test

Who Should Get This Test

The purpose of this test is to identify pathogenic variants in the HS6ST1 gene to confirm a diagnosis of hypogonadotropic hypogonadism type 15 with or without anosmia, guide treatment decisions, and facilitate genetic counseling for affected individuals and their families.

How to Prepare

  • Ensure proper sample labeling
  • Use sterile collection equipment
  • Follow transport guidelines for DNA samples

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"This genetic test is essential for identifying the underlying cause of hypogonadism and anosmia, enabling personalized treatment plans and genetic counseling for affected families."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample VolumeAs required for NGS analysis
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or FTA card spot

Sample Stability

Blood sample: stable for 48 hours at room temperature
FTA card: stable for years if stored properly
Sample Rejection Criteria:
  • Insufficient sample volume
  • Contaminated sample
  • Incorrect sample type

Understanding Your Results

Results indicate the presence or absence of pathogenic variants in the HS6ST1 gene.
Positive result: Pathogenic variant detected, confirming diagnosis
Negative result: No variants detected, but clinical symptoms may require further testing
Variant of uncertain significance: May need additional analysis
⚠️ When to Consult a Doctor:

Consult a geneticist or endocrinologist if symptoms persist or for family planning advice.

Limitations

  • ⚠May not detect all types of genetic variants
  • ⚠Results require clinical correlation
  • ⚠Does not rule out other genetic causes

Risks & Considerations

  • ●Psychological impact of results
  • ●Potential for incidental findings
  • ●No physical risks from blood draw

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA
  • ●Technical errors in sequencing

Compare With Similar Tests

TestHS6ST1 Gene Hypogonadotropic hypogonadism type 15 with or without anosmia NGS Genetic TestKallmann Syndrome PanelHS6ST1 Sequencing
ComparisonHS6ST1 Gene Hypogonadotropic hypogonadism type 15 with or without anosmia NGS Genetic Test

Frequently Asked Questions

What is HS6ST1 Gene Hypogonadotropic Hypogonadism Type 15?
It is a genetic condition caused by mutations in the HS6ST1 gene, leading to hormone deficiencies affecting sexual development and smell.
What are the symptoms of this condition?
Symptoms include delayed puberty, infertility, decreased libido, erectile dysfunction, and anosmia.
How is the test performed?
The test uses Next-Generation Sequencing (NGS) to analyze the HS6ST1 gene from a blood or DNA sample.
What is the cost of the test?
The test costs INR 20000 at DNA Labs India.
Is home sample collection available?
Yes, free home sample collection is available for online bookings across India.
How long does it take to get results?
Results are typically available in 3 to 4 weeks.
What do the results mean?
Results indicate whether pathogenic variants in the HS6ST1 gene are detected, confirming the diagnosis.
Is the test covered by insurance?
Coverage depends on the insurance provider; check with your insurer.
Who should get this test?
Individuals with symptoms of hypogonadism or anosmia, or those with a family history of the condition.
What is the accuracy of the test?
NGS is highly accurate for detecting genetic variants, but results should be interpreted clinically.
Are there any risks associated with the test?
The test involves a blood draw, which has minimal risks. Genetic results may have psychological implications.
How can I prepare for the test?
Provide clinical history, undergo genetic counseling, and ensure proper sample collection.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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