IFN Gamma Quantitative Test
Short Name: IFN-γ Quantitative
Also known as: Interferon Gamma Quantitative, IFN-γ Test, Interferon Gamma Assay
IFN Gamma Quantitative Test test available at DNA Labs India for ₹7,650. Uses Real Time PCR on CSF, Whole Blood, Serum samples. Results in Reports are available by the 3rd working day. Email reports are sent within 36 hours, and phone consultation is available within 24 hours.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The primary purpose of the IFN Gamma Quantitative Test is to quantify the level of Interferon Gamma in the blood or CSF. Elevated levels may indicate an active or latent infection, while low levels may suggest immune suppression. It aids in diagnosing and monitoring conditions like tuberculosis, leprosy, brucellosis, cryptococcosis, and HIV. The test is also used to evaluate the effectiveness of treatment and to assess immune function in immunocompromised patients.
- Test Code
- 6165
- CPT Code
- 86352
- ICD Code
- R76.9
- Price
- ₹7,650
- Sample Type
- CSF, Whole Blood, Serum
- Result Time
- Reports are available by the 3rd working day. Email reports are sent within 36 hours, and phone consultation is available within 24 hours.
- Fasting Required
- No
- Method
- Real Time PCR
Sample Collection
No fasting required. However, inform your doctor about any medications you are taking, especially immunosuppressants. Bring any relevant clinical history and a signed consent document.
Method: Venipuncture or Lumbar Puncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm. If CSF is required, a lumbar puncture will be performed by a healthcare professional. The procedure is quick and generally well-tolerated.
Report Delivery
You can resume normal activities immediately. If you had a lumbar puncture, rest for a short while and drink fluids. Report any unusual symptoms like headache or bleeding to your doctor.
Timeline: Reports are available by the 3rd working day. Email reports are sent within 36 hours, and phone consultation is available within 24 hours.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of the IFN Gamma Quantitative Test is to quantify the level of Interferon Gamma in the blood or CSF. Elevated levels may indicate an active or latent infection, while low levels may suggest immune suppression. It aids in diagnosing and monitoring conditions like tuberculosis, leprosy, brucellosis, cryptococcosis, and HIV. The test is also used to evaluate the effectiveness of treatment and to assess immune function in immunocompromised patients.
How to Prepare
- Consent document must be signed before sample collection
- Bring any clinical history of the patient
- Sample should be shipped immediately after collection
- For home collection, ensure the phlebotomist follows sterile procedures
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"The IFN Gamma Quantitative Test is a valuable tool for evaluating cell-mediated immune responses, particularly in latent tuberculosis and other chronic infections. Results should be interpreted in conjunction with clinical findings and other diagnostic tests."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or lipemic samples
- Improperly labeled samples
- Samples received after prolonged delay without refrigeration
- Insufficient sample volume
Understanding Your Results
Elevated IFN-γ
Recommendation: Further diagnostic workup and clinical correlation
Normal IFN-γ
Recommendation: If symptoms persist, consider other tests
Low IFN-γ
Recommendation: Evaluate immune status and consider additional tests
Consult your healthcare provider if you experience persistent cough, fever, night sweats, unexplained weight loss, skin lesions, or enlarged lymph nodes, especially if you have been exposed to someone with tuberculosis or other infections. Early testing can lead to timely treatment.
Limitations
- ⚠Cannot differentiate between latent and active tuberculosis
- ⚠May be falsely negative in immunocompromised patients
- ⚠Results should be correlated with clinical symptoms and other tests
- ⚠Not a standalone diagnostic test for HIV or other infections
Risks & Considerations
- ●Minor bruising or bleeding at the puncture site
- ●Infection (rare)
- ●Headache after lumbar puncture (if applicable)
Interfering Factors
- ●Recent use of immunosuppressive drugs (e.g., corticosteroids)
- ●Severe immunocompromised states (e.g., advanced HIV)
- ●Sample hemolysis or improper storage
- ●Recent blood transfusion
- ●Concurrent infections
Compare With Similar Tests
| Test | IFN Gamma Quantitative Test | Tuberculin Skin Test (TST) | IGRA (Interferon Gamma Release Assay) |
|---|---|---|---|
| Comparison | IFN Gamma Quantitative Test | TST is a skin test for TB exposure, while IFN-γ test is a blood test that may be more specific and not affected by BCG vaccination. | IGRA is similar to IFN-γ quantitative test but typically uses specific antigens (ESAT-6, CFP-10) to stimulate T cells. The quantitative test measures baseline IFN-γ levels. |
Frequently Asked Questions
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