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IL31RA Gene Amyloidosis, primary localized cutaneous, type 2 NGS Genetic Test

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IL31RA Gene Amyloidosis, primary localized cutaneous, type 2 NGS Genetic Test

Short Name: IL31RA Amyloidosis NGS Test

Also known as: IL31RA-related Amyloidosis, Primary Cutaneous Amyloidosis Type 2

IL31RA Gene Amyloidosis, primary localized cutaneous, type 2 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic TestAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify mutations in the IL31RA gene for accurate diagnosis, management, and family counseling in suspected cases of Primary Localized Cutaneous Amyloidosis Type 2.

Test Code
4842
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Provide clinical history and undergo genetic counseling to draw a pedigree chart.

Method: Venipuncture

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or use of FTA card for one drop of blood.

Step 3

Report Delivery

Apply pressure to the puncture site; monitor for any adverse reactions.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling session to discuss family history and test implications.
2
During the Test:Blood sample collection and processing for NGS analysis.
3
After the Test:Report generation and delivery; follow-up counseling for result interpretation.

About This Test

Who Should Get This Test

To identify mutations in the IL31RA gene for accurate diagnosis, management, and family counseling in suspected cases of Primary Localized Cutaneous Amyloidosis Type 2.

How to Prepare

  • Ensure proper identification
  • Use sterile equipment
  • Label samples correctly

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for IL31RA mutations is essential for accurate diagnosis and can inform treatment strategies, especially in cases with family history. Early intervention can significantly improve patient outcomes."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture

Sample Stability

Blood: 2-8°C for 72 hours
Extracted DNA: -20°C for long-term storage
Sample Rejection Criteria:
  • Hemolyzed or contaminated samples
  • Insufficient sample volume
  • Incorrect labeling

Understanding Your Results

Results indicate the presence or absence of pathogenic variants in the IL31RA gene. Positive results confirm genetic predisposition, while negative results may require further clinical evaluation.
📊

Positive

Pathogenic variant detected; confirms diagnosis. Genetic counseling recommended.

📊

Negative

No pathogenic variants detected. Consider other causes or repeat testing if clinically indicated.

📊

Variant of Uncertain Significance

Genetic variant found but significance unknown. Clinical correlation and family studies advised.

⚠️ When to Consult a Doctor:

Consult a doctor if you experience persistent skin symptoms, have a family history of amyloidosis, or receive positive or uncertain genetic test results.

Limitations

  • ⚠May not detect all genetic variants
  • ⚠Requires genetic counseling for interpretation
  • ⚠Not a standalone diagnostic tool; clinical correlation needed

Risks & Considerations

  • ●Minimal risk from blood draw (bruising, infection)
  • ●Psychological impact of genetic results

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA quality
  • ●Incorrect sample storage

Compare With Similar Tests

TestIL31RA Gene Amyloidosis, primary localized cutaneous, type 2 NGS Genetic TestSkin BiopsyImmunofluorescence TestingSanger Sequencing
ComparisonIL31RA Gene Amyloidosis, primary localized cutaneous, type 2 NGS Genetic Test

Frequently Asked Questions

What is IL31RA Gene Amyloidosis?
It is a rare genetic disorder causing amyloid protein deposition in the skin, leading to symptoms like itching and scaly lesions.
How is the NGS Genetic Test performed?
A blood sample is collected and analyzed using Next-Generation Sequencing to detect mutations in the IL31RA gene.
What is the cost of the test?
The test costs INR 20,000 at DNA Labs India, with home collection available.
Is home sample collection available?
Yes, free home collection is offered for online bookings across India.
How long does it take to get results?
Results are typically available in 3 to 4 weeks.
What are the symptoms of this condition?
Symptoms include persistent itching, redness, swelling, and raised scaly lesions on the skin.
Who should consider this test?
Individuals with skin symptoms suggestive of amyloidosis or a family history of the disorder.
Is genetic counseling included?
Yes, a genetic counseling session is part of the pre-test process.
What if the test is positive?
A positive result confirms genetic predisposition; consult a doctor for management and family screening.
Are there any risks to the test?
Risks are minimal, mainly related to blood draw, such as bruising or infection.
How accurate is the NGS test?
NGS has high accuracy (>99%) for detecting known pathogenic variants in the IL31RA gene.
Can this test be used for family screening?
Yes, it can identify carriers in families, aiding in genetic counseling and early intervention.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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