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Immunohistochemistry Polyoma BK Virus (SV 40) Test

DNA Labs India | ISO 9001:2015 Certified

Immunohistochemistry Polyoma BK Virus (SV 40) Test

Short Name: IHC BK Virus Test

Also known as: BK Virus IHC Test, SV40 Immunohistochemistry, Polyoma Virus Staining

Immunohistochemistry Polyoma BK Virus (SV 40) Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tissue biopsy (formal-saline or FFPE block) samples. Results in 5-7 days from sample receipt at laboratory. Free home collection in 300+ cities across India.

ImmunohistochemistryAdult🏠 Home Collection

🩺 Medically Reviewed By

Overview

To diagnose BK virus infection in kidney tissues, especially in transplant patients, to monitor for nephropathy and guide treatment decisions.

Test Code
1030
Price
₹3,500
Sample Type
Tissue biopsy (formal-saline or FFPE block)
Result Time
5-7 days from sample receipt at laboratory
Fasting Required
No
Method
Immunohistochemistry
Step 1

Sample Collection

Provide histopathology report, site of biopsy, and clinical history. No specific patient preparation required.

Method: Biopsy collection by healthcare professional

Step 2

Laboratory Analysis

Biopsy performed by healthcare professional; tissue fixed immediately in 10% formal-saline or processed as FFPE block.

Step 3

Report Delivery

Sample shipped at room temperature to laboratory; results available in 5-7 days. Monitor biopsy site for complications.

Timeline: 5-7 days from sample receipt at laboratory

Patient Instructions

1
Before the Test:No specific preparation; provide necessary clinical information as pre-test requirement.
2
During the Test:Biopsy collection and sample processing in laboratory using immunohistochemistry method.
3
After the Test:Monitor biopsy site for bleeding or infection; await results via online portal or email.

About This Test

Who Should Get This Test

To diagnose BK virus infection in kidney tissues, especially in transplant patients, to monitor for nephropathy and guide treatment decisions.

How to Prepare

  • Use 10% formal-saline or formalin fixed paraffin embedded (FFPE) block
  • Ship at room temperature
  • Include a copy of histopathology report, biopsy site, and clinical history

Doctor's Notes

Reviewed by — MBBS, MD (Biochemistry) · Reg. No. 21504

"This test is crucial for monitoring BK virus in transplant patients to prevent graft loss and guide antiviral therapy."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTissue biopsy (formal-saline or FFPE block)
Sample VolumeAs required for biopsy
Container10% Formal-saline or Formalin fixed paraffin embedded block
Collection MethodBiopsy collection by healthcare professional

Sample Stability

Room Temperature
Refrigerator
Frozen
Sample Rejection Criteria:
  • Insufficient tissue sample
  • Improper fixation or container
  • Missing clinical information or histopathology report

Understanding Your Results

Results indicate the presence or absence of BK virus antigens in the tissue sample, aiding in diagnosis.
📊

Positive

BK virus detected; suggests active infection or nephropathy, requiring clinical correlation and possible treatment.

📊

Negative

No BK virus detected; but clinical correlation is needed to rule out infection, especially if symptoms persist.

⚠️ When to Consult a Doctor:

If symptoms such as fever, hematuria, or graft dysfunction persist, or if test results are positive, consult a nephrologist promptly.

Limitations

  • Qualitative test only; does not quantify viral load
  • Requires biopsy procedure, which has associated risks
  • May have false negatives if viral load is low or unevenly distributed
  • Not suitable for direct viral detection in blood or urine

Risks & Considerations

  • Biopsy-related bleeding or hematoma
  • Infection at biopsy site
  • Discomfort or pain during biopsy procedure
  • Rare allergic reaction to local anesthesia

Interfering Factors

  • Poor tissue fixation
  • Inadequate sample size
  • Use of incorrect antibodies
  • Tissue necrosis or degradation

Compare With Similar Tests

TestImmunohistochemistry Polyoma BK Virus (SV 40) TestBK Virus PCR QuantitativeSerology for PolyomavirusRenal Function Tests (e.g., Creatinine)Urine Cytology
ComparisonImmunohistochemistry Polyoma BK Virus (SV 40) Test

Frequently Asked Questions

What is the Immunohistochemistry Polyoma BK Virus Test?
It is a diagnostic test that detects BK virus antigens in tissue samples, primarily used to diagnose BK virus nephropathy in kidney transplant patients.
Why is this test important for transplant patients?
BK virus can cause severe kidney damage in transplant recipients; early detection via this test helps prevent graft loss and guides treatment.
How is the sample collected for this test?
A tissue biopsy is collected from the affected area, typically the kidney, and fixed in formal-saline or as an FFPE block.
What symptoms might indicate the need for this test?
Symptoms include fever, hematuria, elevated creatinine, or signs of graft dysfunction in transplant patients.
How long does it take to get the results?
Results are typically available within 5-7 days after sample receipt at the laboratory.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection in many cities across India for online bookings.
What is the cost of the IHC Polyoma BK Virus Test?
The test costs INR 3500, which includes home collection and report delivery services.
Is this test covered by insurance schemes like PMJAY or CGHS?
Coverage depends on the specific insurance policy; it is advisable to check with your provider or DNA Labs India for details.
What does a positive test result mean?
A positive result indicates the presence of BK virus antigens, suggesting active infection that may require medical intervention.
Are there any risks associated with the biopsy procedure?
Risks include bleeding, infection, or discomfort at the biopsy site, but these are generally minimal with proper care.
How accurate is the Immunohistochemistry Polyoma BK Virus Test?
It is highly accurate when performed correctly, but false negatives can occur; clinical correlation is recommended.
Can this test be performed on children?
Yes, it can be used for patients of all ages, but indications and precautions may vary; consult a healthcare provider.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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