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DNA Labs India

Immunosuppressant Drug Profile 1 Test

DNA Labs India | ISO 9001:2015 Certified

Immunosuppressant Drug Profile 1 Test

Also known as: Immunosuppressant Drug Monitoring, Tacrolimus/Sirolimus Assay

Immunosuppressant Drug Profile 1 Test test available at DNA Labs India for ₹11,000. Uses LC-MS/MS on Whole blood samples. Results in Same day report available for samples received by 5 pm.. Free home collection in 300+ cities across India.

Gastroenterology, NephrologyAdults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Ramarao Paidisetty

Dr Ramarao Paidisetty

Consultant Biochemist · Reg: 21504

Last reviewed: September 7, 2026

Overview

To measure blood concentrations of immunosuppressant drugs like tacrolimus and sirolimus for optimizing dosing, avoiding toxicity, and ensuring therapeutic efficacy in patients with autoimmune diseases or transplants.

Test Code
1095
Price
₹11,000
Sample Type
Whole blood
Result Time
Same day report available for samples received by 5 pm.
Fasting Required
No
Method
LC-MS/MS
Step 1

Sample Collection

Provide date & time of sampling, dose taken & time of dosing. No fasting required.

Method: Venipuncture

Step 2

Laboratory Analysis

Standard venipuncture procedure performed by a trained phlebotomist.

Step 3

Report Delivery

Apply pressure to the puncture site to minimize bruising. Resume normal activities.

Timeline: Same day report available for samples received by 5 pm.

Patient Instructions

1
Before the Test:No special preparation required, but ensure to provide accurate dosing information to the healthcare provider.
2
During the Test:A blood sample will be drawn from a vein in your arm.
3
After the Test:You can resume normal activities immediately after the blood draw.

About This Test

Who Should Get This Test

To measure blood concentrations of immunosuppressant drugs like tacrolimus and sirolimus for optimizing dosing, avoiding toxicity, and ensuring therapeutic efficacy in patients with autoimmune diseases or transplants.

How to Prepare

  • Ideal sampling time: Just before the next dose (Trough levels).
  • Provide date & time of sampling, dose taken & time of dosing.
  • Ship refrigerated if not processed immediately.

Doctor's Notes

Reviewed by — MBBS, MD (Biochemistry) · Reg. No. 21504

"This test is crucial for patients on immunosuppressants to avoid toxicity and ensure efficacy, especially in transplant and autoimmune care."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeWhole blood
Sample Volume3 mL (2 mL min.)
ContainerLavender Top (EDTA) tube
Collection MethodVenipuncture

Sample Stability

Room Temperature: 6 hours
Refrigerator: 1 week
Frozen: Not applicable
Sample Rejection Criteria:
  • Incorrect sample type or container
  • Insufficient sample volume
  • Hemolyzed or clotted samples
  • Lack of necessary dosing information

Understanding Your Results

Results should be interpreted by a qualified healthcare provider in the context of the patient's clinical history, symptoms, and other laboratory findings.
Levels above the therapeutic range may indicate toxicity risk, requiring dose adjustment.
Levels below the therapeutic range may suggest subtherapeutic dosing, potentially reducing efficacy.
Consider patient-specific factors like age, kidney function, and concurrent medications.
Trends over time are more informative than single measurements.
⚠️ When to Consult a Doctor:

If you experience symptoms such as dizziness, nausea, swelling, or signs of infection while on immunosuppressants, consult your doctor promptly.

Limitations

  • ⚠Single time point measurement may not reflect overall drug exposure
  • ⚠Therapeutic ranges can vary based on patient condition and lab methods
  • ⚠Not a standalone diagnostic tool; clinical correlation is necessary

Risks & Considerations

  • ●Minor pain or bruising at the puncture site
  • ●Rare risk of infection or fainting
  • ●No significant long-term risks

Interfering Factors

  • ●Hematocrit levels
  • ●Other medications or supplements
  • ●Improper sample handling or storage
  • ●Recent food intake (though not specified, general consideration)

Compare With Similar Tests

TestImmunosuppressant Drug Profile 1 TestImmunoassay for Drug MonitoringRoutine Blood Tests
ComparisonImmunosuppressant Drug Profile 1 TestLC-MS/MS, used in this test, offers higher specificity and accuracy for measuring immunosuppressant levels.This test specifically measures drug concentrations, whereas routine tests may assess general organ function.

Frequently Asked Questions

What is the Immunosuppressant Drug Profile 1 Test?
It is a blood test that measures levels of immunosuppressant drugs like tacrolimus and sirolimus to monitor therapy in autoimmune diseases and transplant patients.
Why is this test important?
It helps ensure drug levels are within the therapeutic range, preventing side effects from high doses and maintaining treatment effectiveness from low doses.
What drugs are measured in this test?
The test measures tacrolimus and sirolimus, which are commonly used immunosuppressants.
How is the test performed?
A blood sample is drawn and analyzed using LC-MS/MS technology for accurate drug concentration measurement.
What is the cost of the test?
The test costs Rs 11000.0 at DNA Labs India, with free home collection across India.
How should I prepare for the test?
Provide the date and time of sampling, dose taken, and time of dosing. No fasting is required, but ideal sampling is just before the next dose.
What are the normal ranges for these drugs?
Typical therapeutic ranges are 5-15 ng/mL for tacrolimus and 4-12 ng/mL for sirolimus, but consult your doctor for personalized interpretation.
What do high levels indicate?
High levels may indicate toxicity risk, leading to symptoms like dizziness or kidney issues, and may require dose adjustment.
What do low levels indicate?
Low levels may suggest subtherapeutic dosing, potentially reducing the drug's effectiveness in managing the condition.
How often should this test be done?
Frequency depends on the patient's condition and treatment plan, often done regularly as advised by the doctor.
Is home collection available for this test?
Yes, DNA Labs India offers free home sample collection for online bookings across many cities in India.
Who should get this test?
Patients on immunosuppressant therapy for autoimmune diseases or organ transplants, or those experiencing symptoms related to these conditions.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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