Infliximab Antibody Test
Also known as: Anti-infliximab antibodies test, Infliximab immunogenicity test
Infliximab Antibody Test test available at DNA Labs India for ₹32,000. Uses Enzyme Immunoassay (EIA) on Serum samples. Results in Results are typically available within 10 days from the date of sample collection.. Free home collection in 300+ cities across India.
Overview
The primary purpose of the Infliximab Antibody Test is to measure the levels of antibodies against infliximab in the blood. This helps in evaluating the immunogenicity of infliximab, assessing treatment efficacy, and identifying the cause of secondary loss of response in patients with autoimmune diseases. It supports personalized medicine by informing therapeutic decisions.
- Test Code
- 24
- Price
- ₹32,000
- Sample Type
- Serum
- Result Time
- Results are typically available within 10 days from the date of sample collection.
- Fasting Required
- No
- Method
- Enzyme Immunoassay (EIA)
Sample Collection
No special preparation required. Inform your healthcare provider about any medications or supplements you are taking.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm using standard venipuncture procedure. The process is quick and minimally invasive.
Report Delivery
Apply pressure to the puncture site with a bandage. Resume normal activities. Mild bruising may occur.
Timeline: Results are typically available within 10 days from the date of sample collection.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of the Infliximab Antibody Test is to measure the levels of antibodies against infliximab in the blood. This helps in evaluating the immunogenicity of infliximab, assessing treatment efficacy, and identifying the cause of secondary loss of response in patients with autoimmune diseases. It supports personalized medicine by informing therapeutic decisions.
How to Prepare
- Use a Serum Separator Tube (SST) for collection
- Ship samples refrigerated (2-8°C) or frozen (-20°C) to maintain stability
- Ensure proper labeling and documentation
Doctor's Notes
"This test is essential for detecting antibody formation against infliximab, which can reduce drug efficacy and worsen symptoms in autoimmune patients. Early detection allows for timely treatment adjustments."
Test Parameters & Specifications
Sample Stability
- Hemolyzed or lipemic samples
- Samples collected in incorrect tubes
- Insufficient sample volume
- Samples not stored properly during transport
Understanding Your Results
Negative
No detectable antibodies against infliximab; treatment may remain effective. Continue monitoring as per physician advice.
Positive
Antibodies detected, indicating potential loss of response or immunogenicity. Consult your doctor for possible dosage changes, drug switching, or addition of immunomodulators.
Equivocal/Borderline
Results near the cut-off value; repeat testing or additional tests (e.g., infliximab trough levels) may be recommended.
Consult your healthcare provider if you experience increased symptoms such as joint pain, fatigue, skin rashes, or gastrointestinal issues while on infliximab therapy, or if your test results are positive.
Limitations
- ⚠Does not measure infliximab drug levels; separate tests may be needed
- ⚠False negatives possible in low antibody titers
- ⚠Not a standalone diagnostic; clinical correlation is essential
- ⚠Test performance may vary based on assay specificity
Risks & Considerations
- ●Minor bruising or swelling at the puncture site
- ●Rare cases of fainting or dizziness during blood draw
- ●Minimal risk of infection (standard precautions taken)
Interfering Factors
- ●Other biologic therapies or immunosuppressive medications
- ●High levels of rheumatoid factor (RF) may cause false positives
- ●Sample hemolysis or improper storage
- ●Recent infliximab infusion (may affect antibody detection)
Compare With Similar Tests
| Test | Infliximab Antibody Test | Infliximab Drug Level Test | C-Reactive Protein (CRP) Test |
|---|---|---|---|
| Comparison | Infliximab Antibody Test |
Frequently Asked Questions
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