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KCNJ5 Gene Hyperaldosteronism type 3 NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

KCNJ5 Gene Hyperaldosteronism type 3 NGS Genetic Test

Short Name: KCNJ5 Hyperaldosteronism Type 3 Test

Also known as: KCNJ5 Gene Test, Hyperaldosteronism Type 3 Genetic Test, Familial Hyperaldosteronism Type 3 Test

KCNJ5 Gene Hyperaldosteronism type 3 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks from sample receipt. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify mutations in the KCNJ5 gene that cause Hyperaldosteronism type 3, aiding in accurate diagnosis, treatment selection, and genetic counseling.

Test Code
5423
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks from sample receipt
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

No specific preparation required. For saliva samples, avoid eating or drinking 30 minutes prior.

Method: Venipuncture or Saliva Collection

Step 2

Laboratory Analysis

Blood sample collected via venipuncture; saliva sample collected using a sterile kit.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising. Store samples as instructed.

Timeline: 3 to 4 weeks from sample receipt

Patient Instructions

1
Before the Test:No fasting required. Provide clinical history and family pedigree if possible.
2
During the Test:Sample collection takes a few minutes; analysis performed in the lab using NGS technology.
3
After the Test:Results delivered in 3-4 weeks. Follow-up with healthcare provider for interpretation.

About This Test

Who Should Get This Test

To identify mutations in the KCNJ5 gene that cause Hyperaldosteronism type 3, aiding in accurate diagnosis, treatment selection, and genetic counseling.

How to Prepare

  • Ensure proper labeling of samples
  • Use sterile collection containers
  • Transport samples at ambient temperature unless specified otherwise

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"This test is essential for confirming genetic causes of hypertension and guiding personalized treatment in patients with suspected hyperaldosteronism."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume3-5 ml blood or equivalent
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or Saliva Collection

Sample Stability

Sample Rejection Criteria:
  • Hemolyzed or clotted blood samples
  • Insufficient sample volume
  • Improperly labeled or contaminated samples

Understanding Your Results

Results indicate the presence or absence of mutations in the KCNJ5 gene associated with Hyperaldosteronism type 3.
📊

Positive

Pathogenic mutation detected, confirming diagnosis of Hyperaldosteronism type 3. Genetic counseling recommended.

📊

Negative

No known pathogenic mutation detected. Clinical correlation and further testing may be needed.

⚠️ When to Consult a Doctor:

If symptoms persist or worsen, or if there is a family history of hyperaldosteronism, consult an endocrinologist or genetic specialist.

Limitations

  • ⚠May not detect all types of mutations in the KCNJ5 gene
  • ⚠Requires genetic counseling for interpretation
  • ⚠Not a standalone diagnostic tool; clinical correlation is necessary

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or infection
  • ●No significant risks from saliva collection

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA
  • ●Improper sample handling or storage

Compare With Similar Tests

TestKCNJ5 Gene Hyperaldosteronism type 3 NGS Genetic TestCYP11B2 Gene TestAldosterone Renin Ratio Test
ComparisonKCNJ5 Gene Hyperaldosteronism type 3 NGS Genetic TestFocuses on another gene involved in aldosterone synthesis; may be used for differential diagnosis.Biochemical test for primary aldosteronism; genetic test provides definitive diagnosis.

Frequently Asked Questions

What is the KCNJ5 Gene Hyperaldosteronism type 3 NGS Genetic Test?
It is a genetic test that uses next-generation sequencing to detect mutations in the KCNJ5 gene, which cause Hyperaldosteronism type 3.
Who should consider getting this test?
Individuals with unexplained hypertension, family history of hyperaldosteronism, or symptoms like headaches and fatigue.
How is the test performed?
A blood or saliva sample is collected and analyzed using NGS technology to identify gene mutations.
What is the cost of the test?
The test costs INR 20000, with free home sample collection available across India.
Is home sample collection available?
Yes, free home collection is offered in many cities nationwide.
How long does it take to get results?
Results are typically available within 3 to 4 weeks.
What do the results mean?
A positive result confirms a genetic mutation, while a negative result may require further evaluation.
Is the test covered by insurance?
Coverage varies; check with your insurance provider. It is not typically covered under government schemes.
Are there any risks associated with the test?
Risks are minimal, such as bruising from blood draw. No significant risks from saliva collection.
Can this test be used for prenatal diagnosis?
It is not typically used for prenatal diagnosis; consult a genetic counselor for prenatal options.
What is the accuracy of the test?
The test is highly accurate due to advanced NGS technology, but genetic counseling is recommended for interpretation.
How do I prepare for the test?
No special preparation is needed. For saliva samples, avoid eating or drinking 30 minutes before collection.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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