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KCNQ4 Gene Deafness, autosomal dominant type 2A NGS Genetic Test

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KCNQ4 Gene Deafness, autosomal dominant type 2A NGS Genetic Test

Short Name: KCNQ4 Deafness NGS Genetic Test

Also known as: DFNA2A, Autosomal Dominant Deafness Type 2A

KCNQ4 Gene Deafness, autosomal dominant type 2A NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Results are typically available within 3 to 4 weeks after sample receipt.. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of the KCNQ4 Gene Deafness NGS Genetic Test is to identify mutations in the KCNQ4 gene associated with autosomal dominant hearing loss, enabling accurate diagnosis, family planning, and personalized management.

Test Code
2302
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
Results are typically available within 3 to 4 weeks after sample receipt.
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Genetic counseling is recommended before testing to understand implications and family history.

Method: Venipuncture or FTA Card

Step 2

Laboratory Analysis

Standard blood draw or finger prick for FTA card collection by a trained professional.

Step 3

Report Delivery

Sample is sent to the laboratory for NGS analysis; follow-up with genetic counselor for results.

Timeline: Results are typically available within 3 to 4 weeks after sample receipt.

Patient Instructions

1
Before the Test:Consult with a genetic counselor to discuss family history, symptoms, and implications of testing.
2
During the Test:Sample collection via blood draw or FTA card; procedure is quick and minimally invasive.
3
After the Test:Receive results in 3-4 weeks; discuss findings with a genetic counselor or doctor for next steps.

About This Test

Who Should Get This Test

The purpose of the KCNQ4 Gene Deafness NGS Genetic Test is to identify mutations in the KCNQ4 gene associated with autosomal dominant hearing loss, enabling accurate diagnosis, family planning, and personalized management.

How to Prepare

  • No fasting required
  • Bring a valid ID and doctor's prescription if available
  • Ensure sample is properly labeled and stored

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Consult a genetic counselor if you have a family history of hearing loss or symptoms like tinnitus and progressive hearing loss."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture or FTA Card

Sample Stability

Blood sample stable for 48 hours at room temperature
FTA card samples stable for several days at room temperature
Sample Rejection Criteria:
  • Hemolyzed or clotted blood samples
  • Insufficient sample volume
  • Improperly labeled or contaminated samples

Understanding Your Results

Results from the KCNQ4 Gene Deafness NGS Genetic Test indicate the presence or absence of mutations associated with autosomal dominant hearing loss.
Positive: Pathogenic mutation detected, confirming risk of KCNQ4-related deafness; genetic counseling advised.
Negative: No pathogenic variants found, reducing likelihood of KCNQ4-related deafness but not excluding other causes.
Variant of Uncertain Significance (VUS): A variant with unknown clinical significance; further testing or family studies may be needed.
⚠️ When to Consult a Doctor:

Consult a genetic counselor or ENT specialist if you experience progressive hearing loss, tinnitus, or have a family history of deafness for proper diagnosis and management.

Limitations

  • ⚠May not detect all types of KCNQ4 gene mutations
  • ⚠Results require interpretation by a genetic counselor
  • ⚠Does not rule out other causes of hearing loss

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or discomfort
  • ●Psychological impact of genetic results; counseling support available

Interfering Factors

  • ●Sample contamination during collection
  • ●Insufficient DNA quality or quantity
  • ●Previous blood transfusions may affect results

Compare With Similar Tests

TestKCNQ4 Gene Deafness, autosomal dominant type 2A NGS Genetic TestGJB2 Gene Mutation AnalysisSLC26A4 Gene TestTMC1 Gene Deafness TestTMPRSS3 Gene Test
ComparisonKCNQ4 Gene Deafness, autosomal dominant type 2A NGS Genetic Test

Frequently Asked Questions

What is KCNQ4 gene deafness?
KCNQ4 gene deafness is a rare genetic condition causing hearing loss due to mutations in the KCNQ4 gene, inherited in an autosomal dominant pattern.
How is KCNQ4 gene deafness inherited?
It is autosomal dominant, meaning a child has a 50% chance of inheriting the condition if one parent carries the mutation.
What are the symptoms of KCNQ4 gene deafness?
Symptoms include progressive hearing loss, tinnitus, difficulty hearing in noisy environments, and trouble understanding speech, often starting in childhood.
How is KCNQ4 gene deafness diagnosed?
Diagnosis is through a genetic test using next-generation sequencing (NGS) to analyze the KCNQ4 gene for mutations.
What is the cost of the KCNQ4 gene deafness NGS Genetic Test?
The test costs INR 20,000, inclusive of sample collection and report delivery.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for this test across India.
How long does it take to get results?
Results are typically delivered within 3 to 4 weeks after the sample is received.
What should I do if the test is positive?
If positive, consult a genetic counselor or ENT specialist for management options and family risk assessment.
Can KCNQ4 gene deafness be prevented?
Genetic conditions cannot be prevented, but early diagnosis allows for management strategies like hearing aids or cochlear implants.
Is the genetic test accurate?
The NGS test is highly accurate for detecting known mutations, but may not identify all variants; genetic counseling helps interpret results.
Do I need a doctor's prescription for the test?
A prescription is not mandatory, but consulting a genetic counselor or doctor is recommended before testing.
What other genetic tests are available for deafness?
Other tests include GJB2, SLC26A4, TMC1 gene tests, and comprehensive deafness gene panels available at DNA Labs India.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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