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KEAP1 Gene Goitre, multinodular NGS Genetic Test

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KEAP1 Gene Goitre, multinodular NGS Genetic Test

Short Name: KEAP1 Goitre NGS Test

Also known as: Multinodular Goitre, KEAP1-Related Goitre

KEAP1 Gene Goitre, multinodular NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic TestAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify genetic mutations in the KEAP1 gene that may contribute to the development of multinodular goitre, aiding in diagnosis, risk assessment, and personalized treatment planning.

Test Code
5404
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

No specific preparation required. Genetic counseling recommended.

Method: Venipuncture or FTA Card

Step 2

Laboratory Analysis

Blood sample drawn via venipuncture or one drop on FTA card.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling session recommended to discuss family history and test implications.
2
During the Test:Sample collection procedure takes about 10-15 minutes.
3
After the Test:Results will be delivered online; follow-up with healthcare provider advised.

About This Test

Who Should Get This Test

To identify genetic mutations in the KEAP1 gene that may contribute to the development of multinodular goitre, aiding in diagnosis, risk assessment, and personalized treatment planning.

How to Prepare

  • Provide a blood sample or extracted DNA
  • Use FTA card for one drop blood if applicable
  • Ensure sample is labeled correctly

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for KEAP1 mutations can aid in early diagnosis and personalized management of multinodular goitre, particularly in individuals with a family history."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture or FTA Card

Sample Stability

Room TemperatureUp to 7 days for FTA card
RefrigeratedUp to 5 days for blood
Sample Rejection Criteria:
  • Hemolyzed sample
  • Insufficient sample volume
  • Improper labeling

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the KEAP1 gene. Consult a genetic counselor for detailed interpretation.
📊

Positive for pathogenic mutation

Increased genetic risk for multinodular goitre; further clinical evaluation recommended.

📊

Negative for pathogenic mutation

No detected mutations in the KEAP1 gene; risk may be lower but not eliminated.

📊

Variant of uncertain significance

Genetic variant detected but clinical significance unknown; follow-up testing may be needed.

⚠️ When to Consult a Doctor:

If you experience symptoms of goitre, have a family history, or receive abnormal test results, consult an endocrinologist or genetic specialist.

Limitations

  • ⚠Test may not detect all genetic variants
  • ⚠Results require clinical correlation
  • ⚠Not a standalone diagnostic tool

Risks & Considerations

  • ●Minimal risk from blood draw (bruising, infection)
  • ●Psychological impact of genetic results
  • ●Potential for uncertain findings

Frequently Asked Questions

What is the KEAP1 Gene Goitre NGS Genetic Test?
It is a genetic test that uses Next-Generation Sequencing to analyze the KEAP1 gene for mutations associated with multinodular goitre.
How much does the test cost?
The test costs INR 20,000 at DNA Labs India, with free home sample collection across India.
What samples are required for the test?
Blood sample, extracted DNA, or one drop of blood on an FTA card.
How long does it take to get results?
Results are typically available within 3 to 4 weeks.
Is home collection available?
Yes, free home sample collection is available for online bookings in many cities across India.
What are the symptoms of KEAP1 gene goitre?
Symptoms may include neck swelling, difficulty swallowing, hoarseness, increased heart rate, and unexplained weight changes.
How is the test performed?
The test involves analyzing DNA from a blood sample using NGS technology to detect mutations in the KEAP1 gene.
What does a positive result mean?
A positive result indicates a pathogenic mutation in the KEAP1 gene, which may increase the risk for multinodular goitre.
Is the test covered by insurance?
Coverage depends on your insurance policy; check with your provider for details.
Can I get the test if I have no symptoms?
Yes, the test can be done for risk assessment, especially with a family history of goitre.
What is the accuracy of the test?
The test uses advanced NGS technology with high accuracy, but results should be interpreted clinically.
How do I prepare for the test?
No special preparation is needed, but genetic counseling is recommended before testing.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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