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DNA Labs India

KLF11 Gene Maturity-onset diabetes of the young type 7 NGS Genetic Test

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KLF11 Gene Maturity-onset diabetes of the young type 7 NGS Genetic Test

Short Name: KLF11 MODY7 NGS Test

Also known as: MODY7 Genetic Test, KLF11 Gene Mutation Test

KLF11 Gene Maturity-onset diabetes of the young type 7 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

Next-Generation Sequencing (NGS) Genetic TestAdults🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of this test is to detect pathogenic mutations in the KLF11 gene to diagnose Maturity-onset diabetes of the young type 7 (MODY7), enabling accurate diagnosis, personalized management, genetic counseling, and family screening.

Test Code
2154
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Ensure genetic counseling is completed and a pedigree chart is drawn. No specific preparation required, but inform the lab of any medications or medical conditions.

Method: Venipuncture or finger-prick for FTA card

Step 2

Laboratory Analysis

A blood sample is collected via venipuncture or a drop on FTA card. The process is quick, minimally invasive, and performed by trained phlebotomists.

Step 3

Report Delivery

Apply pressure to the puncture site to stop bleeding. Resume normal activities. Store samples as instructed for stability.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling and pedigree analysis are recommended before the test to understand implications and obtain informed consent.
2
During the Test:The test involves DNA extraction from the sample and NGS analysis. The process is automated, precise, and conducted in a certified laboratory.
3
After the Test:Results are analyzed by genetic experts, and a comprehensive clinical report is generated. Follow-up counseling may be arranged.

About This Test

Who Should Get This Test

The purpose of this test is to detect pathogenic mutations in the KLF11 gene to diagnose Maturity-onset diabetes of the young type 7 (MODY7), enabling accurate diagnosis, personalized management, genetic counseling, and family screening.

How to Prepare

  • No fasting required for this genetic test
  • Bring valid ID and prescription
  • Inform staff of any bleeding disorders or allergies
  • Ensure the sample is labeled correctly with patient details

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early genetic testing for MODY7 can guide treatment plans and family counseling, especially in reproductive health contexts."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume5 mL
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or finger-prick for FTA card

Sample Stability

Blood in EDTA: stable for 24 hours at 2-8°C
Extracted DNA: stable for long-term at -20°C
FTA card: stable at room temperature for extended periods
Sample Rejection Criteria:
  • Hemolyzed or clotted blood sample
  • Insufficient sample volume
  • Incorrect sample type
  • Unlabeled or mislabeled sample

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the KLF11 gene associated with MODY7, guiding clinical decisions.
📊

Positive for KLF11 mutation

Diagnosis of MODY7 is likely. Consult a geneticist for management, treatment adjustments, and family screening recommendations.

📊

Negative for KLF11 mutation

MODY7 is unlikely. Consider other forms of diabetes or further clinical evaluation based on symptoms.

⚠️ When to Consult a Doctor:

If you have symptoms of diabetes, a family history of MODY, or if the test result is positive, consult a healthcare professional for personalized advice on management and genetic counseling.

Limitations

  • May not detect all variants in the KLF11 gene
  • Requires interpretation by a genetic specialist
  • Not a substitute for clinical diagnosis

Risks & Considerations

  • Minimal risk from blood draw, such as bruising or infection
  • Genetic information may have psychological or emotional impact
  • False negatives are possible but rare with advanced NGS technology

Interfering Factors

  • DNA degradation due to improper storage
  • Contamination of sample
  • Insufficient DNA quantity

Compare With Similar Tests

TestKLF11 Gene Maturity-onset diabetes of the young type 7 NGS Genetic TestHNF1A Gene MODY1 NGS TestGCK Gene MODY2 NGS TestGeneral Diabetes Genetic PanelFasting Glucose Test
ComparisonKLF11 Gene Maturity-onset diabetes of the young type 7 NGS Genetic Test

Frequently Asked Questions

What is the KLF11 Gene MODY7 NGS Genetic Test?
It is a genetic test that uses next-generation sequencing to detect mutations in the KLF11 gene, which causes Maturity-onset diabetes of the young type 7 (MODY7).
Who should consider getting this test?
Young adults with mild hyperglycemia, symptoms of diabetes, or a family history of MODY should consider this test for accurate diagnosis.
What is the cost of the test?
The test costs INR 20000, which includes sample collection, analysis, and a genetic counseling session.
How is the sample collected for this test?
The sample can be collected via blood draw or a finger-prick on an FTA card. Home collection is available across India.
Is fasting required for this genetic test?
No, fasting is not required for this test as it analyzes genetic material, not blood glucose levels.
How long does it take to get results?
Results are typically available in 3 to 4 weeks and are delivered via online portal, email, or WhatsApp.
What does a positive result mean?
A positive result indicates the presence of a KLF11 gene mutation, confirming a diagnosis of MODY7. Consult a geneticist for management.
What does a negative result mean?
A negative result means no KLF11 mutation was detected, making MODY7 unlikely. Further evaluation for other diabetes types may be needed.
Is genetic counseling included with the test?
Yes, the test includes a genetic counseling session to draw a family pedigree chart and discuss implications.
Can this test be done at home?
Yes, DNA Labs India offers free home sample collection for online bookings across numerous cities in India.
What are the common symptoms of MODY7?
Symptoms include increased thirst, frequent urination, blurred vision, fatigue, and skin infections, but they may be mild or absent.
How accurate is the NGS genetic test for MODY7?
NGS technology provides high accuracy in detecting mutations, but results should be interpreted by a genetic specialist for clinical validation.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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