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KRT10 Gene Epidermolytic hyperkeratosis NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

KRT10 Gene Epidermolytic hyperkeratosis NGS Genetic Test

Short Name: EHK KRT10 NGS Test

Also known as: Epidermolytic Hyperkeratosis (EHK), KRT10-related Hyperkeratosis

KRT10 Gene Epidermolytic hyperkeratosis NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS (Next-Generation Sequencing) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To diagnose Epidermolytic Hyperkeratosis and determine the specific mutation in the KRT10 gene for treatment planning and genetic counseling.

Test Code
2406
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS (Next-Generation Sequencing)
Step 1

Sample Collection

Clinical history of patient and genetic counseling session to draw a pedigree chart of affected family members.

Step 2

Laboratory Analysis

Blood sample collection via venipuncture or using FTA card for one drop blood.

Step 3

Report Delivery

Sample sent to DNA Labs India for NGS analysis.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling session is recommended to understand the test implications.
2
During the Test:Simple blood draw with minimal discomfort.
3
After the Test:Results available in 3-4 weeks; genetic counseling provided to interpret findings.

About This Test

Who Should Get This Test

To diagnose Epidermolytic Hyperkeratosis and determine the specific mutation in the KRT10 gene for treatment planning and genetic counseling.

How to Prepare

  • Use sterile blood collection tubes
  • Label samples correctly with patient details
  • Store at ambient room temperature until shipment

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"As a geneticist, I recommend the KRT10 NGS test for accurate diagnosis of epidermolytic hyperkeratosis, enabling personalized treatment and genetic counseling for affected families."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card

Sample Stability

Blood samples stable for 7 days at room temperature
Extracted DNA stable for longer periods at -20°C
Sample Rejection Criteria:
  • Hemolyzed or contaminated samples
  • Insufficient sample volume
  • Improperly labeled samples

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the KRT10 gene associated with Epidermolytic Hyperkeratosis.
📊

Pathogenic variant detected

Confirms diagnosis of EHK; genetic counseling recommended for family planning.

📊

No pathogenic variant detected

Does not rule out EHK if clinical symptoms persist; consider other genetic tests.

📊

Variant of uncertain significance

Further testing or family studies may be needed for clarification.

⚠️ When to Consult a Doctor:

If symptoms of Epidermolytic Hyperkeratosis are present, or for genetic counseling after a positive result.

Limitations

  • ⚠May not detect all types of mutations in the KRT10 gene
  • ⚠Results require interpretation by a geneticist
  • ⚠Not a standalone diagnostic tool; clinical correlation is necessary

Risks & Considerations

  • ●Minor bruising or discomfort at blood draw site
  • ●Emotional impact of genetic results

Frequently Asked Questions

What is the KRT10 Gene Epidermolytic Hyperkeratosis NGS Genetic Test?
It is a genetic test using next-generation sequencing to detect mutations in the KRT10 gene, which causes Epidermolytic Hyperkeratosis, a rare skin disorder.
How much does the test cost?
The test costs INR 20000 at DNA Labs India, which includes the genetic test, result interpretation, and genetic counseling.
What is the turnaround time for results?
Results are typically available in 3 to 4 weeks after sample collection.
Is home sample collection available?
Yes, free home sample collection is available for online bookings across numerous cities in India.
What samples are required for the test?
Blood, extracted DNA, or one drop of blood on an FTA card can be used.
How accurate is the NGS genetic test?
NGS technology is highly accurate for detecting mutations, but results should be correlated with clinical symptoms and interpreted by a geneticist.
Can this test be used for prenatal diagnosis?
Consult a genetic counselor to discuss prenatal testing options, as this test may be part of a broader genetic evaluation.
What are the symptoms of Epidermolytic Hyperkeratosis?
Symptoms include thick, scaly skin, blisters, redness, painful cracking, and difficulty regulating body temperature.
How is the test performed?
A blood sample is collected and analyzed using next-generation sequencing to identify mutations in the KRT10 gene.
What should I do before getting tested?
Provide clinical history and undergo a genetic counseling session to draw a family pedigree chart.
Are there any risks associated with the test?
Risks are minimal, such as minor bruising from blood draw, but emotional impact from results may occur.
How can I get genetic counseling?
DNA Labs India includes genetic counseling with the test; contact them for details on scheduling sessions.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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