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DNA Labs India

LEFTY2 Gene Left-right axis malformations NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

LEFTY2 Gene Left-right axis malformations NGS Genetic Test

Short Name: LEFTY2 Gene NGS Test

Also known as: Left-right determination factor 2 gene test, LEFTY2 mutation analysis, Heterotaxy genetic test

LEFTY2 Gene Left-right axis malformations NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS (Next-Generation Sequencing) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic TestPediatric🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To diagnose left-right axis malformations caused by LEFTY2 gene mutations, enabling personalized treatment and genetic counseling.

Test Code
2755
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
NGS (Next-Generation Sequencing)
Step 1

Sample Collection

No specific preparation required. Provide clinical history and undergo genetic counseling.

Method: Venipuncture for blood, or FTA card for one drop blood

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or one drop on FTA card by trained phlebotomist.

Step 3

Report Delivery

Sample sent to lab for processing. Monitor for any discomfort at collection site.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Genetic counseling and clinical history review recommended.
2
During the Test:Sample collection and processing in laboratory.
3
After the Test:Report delivery and follow-up consultation with geneticist.

About This Test

Who Should Get This Test

To diagnose left-right axis malformations caused by LEFTY2 gene mutations, enabling personalized treatment and genetic counseling.

How to Prepare

  • Ensure proper identification
  • Use sterile equipment
  • Label samples correctly
  • Transport at ambient temperature

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early genetic testing for LEFTY2 mutations is crucial for managing left-right axis malformations, enabling personalized care and informed family planning."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture for blood, or FTA card for one drop blood

Sample Stability

Blood: 24 hours at room temperature
FTA card: Stable for weeks at room temperature
Sample Rejection Criteria:
  • Hemolyzed samples
  • Insufficient volume
  • Improper labeling

Understanding Your Results

Results indicate the presence or absence of pathogenic variants in the LEFTY2 gene. Consult a geneticist for detailed interpretation.
Positive result: Pathogenic variant detected, indicating genetic cause for malformations
Negative result: No pathogenic variants found, but clinical correlation needed
Variant of uncertain significance: Requires further testing and counseling
⚠️ When to Consult a Doctor:

Consult a doctor if symptoms of left-right axis malformations are present, such as heart defects, breathing issues, or organ abnormalities, or if family history suggests genetic risk.

Limitations

  • ⚠Test may not detect all genetic variants
  • ⚠Requires genetic counseling for interpretation
  • ⚠Results should be correlated with clinical findings

Risks & Considerations

  • ●Minimal physical risk from blood draw
  • ●Psychological impact of genetic results

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA
  • ●Technical errors in sequencing

Frequently Asked Questions

What is the LEFTY2 Gene?
The LEFTY2 gene, also known as left-right determination factor 2, is critical for establishing left-right asymmetry in embryonic development.
What are left-right axis malformations?
These are congenital disorders affecting organ placement, leading to conditions like heart defects, lung abnormalities, and skeletal issues.
Who should get this test?
Individuals suspected of having left-right axis malformations, with symptoms such as heart defects, breathing difficulties, or family history of congenital disorders.
How is the test performed?
The test uses NGS technology to analyze the LEFTY2 gene from a blood or DNA sample.
What is the cost of the test?
The cost is INR 20,000, including sample collection, DNA extraction, sequencing, and analysis.
How long does it take to get results?
Results are typically available within 3 to 4 weeks.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection across India.
What do the results mean?
Results indicate the presence or absence of pathogenic variants in the LEFTY2 gene. Consult a geneticist for interpretation.
Are there any risks associated with the test?
Risks are minimal, primarily related to blood draw, but genetic results may have psychological implications.
How accurate is the NGS test?
NGS is highly accurate for detecting genetic variants, but results should be correlated with clinical findings.
Can this test be used for prenatal diagnosis?
This test is typically postnatal; consult a geneticist for prenatal testing options.
What should I do after receiving the results?
Discuss results with a geneticist or healthcare provider for personalized management and counseling.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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