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DNA Labs India

LHCGR Gene Leydig cell hypoplasia type 1 NGS Genetic Test

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LHCGR Gene Leydig cell hypoplasia type 1 NGS Genetic Test

Short Name: LHCGR Leydig Cell Hypoplasia Type 1 Test

Also known as: LHCGR Gene Mutation Test, Leydig Cell Hypoplasia Genetic Test

LHCGR Gene Leydig cell hypoplasia type 1 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood, Extracted DNA, or FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

Genetic TestMaleAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of this test is to identify mutations in the LHCGR gene that cause Leydig cell hypoplasia type 1, aiding in accurate diagnosis and personalized treatment planning.

Test Code
5540
Price
₹20,000
Sample Type
Blood, Extracted DNA, or FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
Next Generation Sequencing (NGS)
Step 1

Sample Collection

Genetic counseling session recommended.

Method: Blood draw or cheek swab

Step 2

Laboratory Analysis

Blood draw or cheek swab performed by trained professional.

Step 3

Report Delivery

Sample sent to lab for analysis.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Genetic counseling and clinical history review.
2
During the Test:Sample collection and processing.
3
After the Test:Analysis and report generation.

About This Test

Who Should Get This Test

The purpose of this test is to identify mutations in the LHCGR gene that cause Leydig cell hypoplasia type 1, aiding in accurate diagnosis and personalized treatment planning.

How to Prepare

  • Ensure proper sample collection
  • Avoid contamination
  • Label samples correctly

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early genetic testing for LHCGR mutations can guide treatment and family planning for Leydig cell hypoplasia."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood, Extracted DNA, or FTA Card
Collection MethodBlood draw or cheek swab

Sample Stability

Blood samples stable for 48 hours at room temperature
Extracted DNA stable for longer periods
Sample Rejection Criteria:
  • Hemolyzed samples
  • Insufficient sample volume
  • Improperly labeled samples

Understanding Your Results

Results indicate the presence or absence of mutations in the LHCGR gene.
Positive result: Pathogenic mutation detected, consistent with Leydig cell hypoplasia type 1.
Negative result: No pathogenic mutations detected, but clinical correlation is advised.
Variant of uncertain significance: Further testing or family studies may be needed.
⚠️ When to Consult a Doctor:

If symptoms of Leydig cell hypoplasia are present or if there is a family history of the condition.

Limitations

  • ⚠May not detect all mutations
  • ⚠Requires genetic counseling for interpretation
  • ⚠Not a standalone diagnostic tool

Risks & Considerations

  • ●Minimal risk from blood draw
  • ●Psychological impact of genetic results

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA
  • ●Hemolyzed blood sample

Frequently Asked Questions

What is the LHCGR Gene Leydig Cell Hypoplasia Type 1 NGS Genetic Test?
It is a genetic test that uses Next Generation Sequencing to detect mutations in the LHCGR gene, which cause Leydig cell hypoplasia type 1, a disorder affecting male genital development.
Who should take this test?
Individuals with symptoms such as absent or incomplete male genitalia, undescended testes, infertility, abnormal hormone levels, delayed puberty, or a family history of the condition.
How is the test performed?
The test requires a blood sample or cheek swab, which is analyzed using NGS technology to identify mutations in the LHCGR gene.
What is the cost of the test?
The cost is INR 20,000, which includes test kit, sample collection, and analysis. Home collection is available for free.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection across India for this test.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
What do the results mean?
A positive result indicates pathogenic mutations in the LHCGR gene, confirming Leydig cell hypoplasia type 1. A negative result means no mutations were detected, but clinical correlation is advised.
Is genetic counseling required?
Yes, genetic counseling is recommended before and after testing to understand the implications and guide treatment.
Are there any risks associated with the test?
Risks are minimal, such as slight discomfort from blood draw, but there may be psychological impacts from genetic results.
Can this test be used for carrier testing?
Yes, it can identify carriers of LHCGR mutations, which is useful for family planning.
What is Leydig cell hypoplasia type 1?
It is a rare genetic disorder where Leydig cells in the testes do not develop properly, leading to impaired testosterone production and male genital abnormalities.
How accurate is the NGS technology for this test?
NGS technology provides high accuracy for detecting mutations in the LHCGR gene, but results should be interpreted by a genetic specialist.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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