LHX4 Gene Pituitary hormone deficiency, combined type 4 NGS Genetic Test
Short Name: LHX4 Gene Pituitary Hormone Deficiency Test
Also known as: LHX4-related pituitary hormone deficiency, Combined pituitary hormone deficiency type 4, LHX4 gene disorder
LHX4 Gene Pituitary hormone deficiency, combined type 4 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to diagnose genetic predisposition to pituitary hormone deficiency by detecting pathogenic variants in the LHX4 gene. It aids in confirming clinical diagnoses, guiding treatment strategies, and facilitating genetic counseling for families at risk.
- Test Code
- 5483
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next Generation Sequencing (NGS)
Sample Collection
No specific preparation required. Provide clinical history and family pedigree during genetic counseling.
Method: Venipuncture for blood or saliva collection
Laboratory Analysis
Sample collected via venipuncture or saliva. Ensure proper labeling and handling.
Report Delivery
Sample sent to lab for analysis. Follow up for report delivery.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to diagnose genetic predisposition to pituitary hormone deficiency by detecting pathogenic variants in the LHX4 gene. It aids in confirming clinical diagnoses, guiding treatment strategies, and facilitating genetic counseling for families at risk.
How to Prepare
- Fast for 4-8 hours if required for blood draw
- Avoid eating or drinking before saliva collection
- Use sterile containers for sample collection
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This genetic test is crucial for early diagnosis and management of pituitary hormone deficiency, especially in families with a history of endocrine disorders. It helps in personalized treatment planning and genetic counseling."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Insufficient sample volume
- Incorrect sample type
Understanding Your Results
Pathogenic variant detected
Confirms diagnosis of LHX4-related pituitary hormone deficiency. Recommend genetic counseling and treatment.
Variant of uncertain significance
Further testing or family studies may be needed.
No pathogenic variant detected
Genetic cause unlikely, but clinical evaluation should continue.
Consult a doctor if symptoms persist, for treatment options, or for genetic counseling after receiving test results.
Limitations
- ⚠May not detect all genetic variants
- ⚠Results require clinical correlation
- ⚠Limited to LHX4 gene analysis
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection
- ●Psychological impact of genetic results
Interfering Factors
- ●Contaminated sample
- ●Improper sample storage
- ●Recent blood transfusion
Compare With Similar Tests
| Test | LHX4 Gene Pituitary hormone deficiency, combined type 4 NGS Genetic Test | GH1 Gene Test | PROP1 Gene Test | POU1F1 Gene Test | Whole Exome Sequencing |
|---|---|---|---|---|---|
| Comparison | LHX4 Gene Pituitary hormone deficiency, combined type 4 NGS Genetic Test | For growth hormone deficiency, different gene involved. | For combined pituitary hormone deficiency, different genetic basis. | For pituitary hormone deficiency, related but distinct gene. | Broader genetic analysis, not specific to LHX4. |
Frequently Asked Questions
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₹20,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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