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LIPI Gene Hypertriglyceridemia, susceptibility to NGS Genetic Test

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LIPI Gene Hypertriglyceridemia, susceptibility to NGS Genetic Test

Short Name: LIPI Gene NGS Test

Also known as: Lipid Panel Plus Test, Hypertriglyceridemia Genetic Susceptibility Test, LIPI Gene Sequencing

LIPI Gene Hypertriglyceridemia, susceptibility to NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of this test is to identify genetic variants in the LIPI gene and related genes that increase susceptibility to hypertriglyceridemia. It helps in assessing genetic risk for high triglycerides, guiding preventive measures, and informing personalized healthcare decisions.

Test Code
2102
Price
₹20,000
Sample Type
Blood or Extracted DNA
Result Time
3 to 4 Weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Genetic counseling is recommended to discuss test implications, benefits, and limitations. Provide clinical and family history.

Method: Venipuncture or FTA card

Step 2

Laboratory Analysis

Blood sample is drawn via venipuncture, or a DNA sample is extracted. One drop blood on FTA card may be used.

Step 3

Report Delivery

Sample is transported to the laboratory for NGS analysis. Maintain ambient room temperature during transport.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling to discuss implications, risks, and benefits. Provide informed consent and medical history.
2
During the Test:No special procedure during NGS test; it is performed in the laboratory on the collected sample.
3
After the Test:Results are reviewed with a genetic counselor or healthcare provider. Follow-up actions based on findings.

About This Test

Who Should Get This Test

The purpose of this test is to identify genetic variants in the LIPI gene and related genes that increase susceptibility to hypertriglyceridemia. It helps in assessing genetic risk for high triglycerides, guiding preventive measures, and informing personalized healthcare decisions.

How to Prepare

  • Ensure proper labeling of sample with patient details
  • Avoid hemolysis in blood samples by gentle handling
  • Follow instructions for FTA card usage if applicable

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for LIPI gene variants can aid in early identification and personalized management of hypertriglyceridemia risk, especially in individuals with family history or symptoms."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA
Sample VolumeNot specified
ContainerEDTA tube or equivalent
Collection MethodVenipuncture or FTA card

Sample Stability

Blood samples stable at room temperature for up to 48 hours
Extracted DNA stable at -20°C for long-term storage
Sample Rejection Criteria:
  • Insufficient sample volume
  • Improperly labeled or unlabeled samples
  • Contaminated or hemolyzed samples
  • Incorrect sample type or container

Understanding Your Results

Interpretation of results for LIPI gene and related genetic variants in hypertriglyceridemia susceptibility. Results should be reviewed by a genetic counselor or healthcare provider.
📊

Positive for pathogenic variants

Increased genetic susceptibility to hypertriglyceridemia; recommend lifestyle modifications, monitoring, and possible medical consultation.

📊

Negative for pathogenic variants

No detected genetic variants in analyzed genes; risk may be influenced by other factors; maintain healthy lifestyle.

📊

Variant of uncertain significance (VUS)

Further research needed; clinical correlation and follow-up recommended.

⚠️ When to Consult a Doctor:

Consult a geneticist, lipid specialist, or cardiologist if results indicate positive for genetic variants, or if there is a family history of hypertriglyceridemia or cardiovascular disease.

Limitations

  • Test may not detect all genetic variants associated with hypertriglyceridemia
  • Results indicate susceptibility, not diagnosis; clinical correlation is essential
  • Genetic risk factors interact with environmental and lifestyle factors
  • Test accuracy depends on sample quality and sequencing technology

Risks & Considerations

  • Potential psychological impact of genetic results, such as anxiety
  • Data privacy concerns related to genetic information
  • No physical risks beyond standard blood collection

Interfering Factors

  • DNA quality issues due to sample degradation
  • Sample contamination during collection or processing
  • Incorrect sample storage conditions

Compare With Similar Tests

TestLIPI Gene Hypertriglyceridemia, susceptibility to NGS Genetic TestStandard Lipid PanelOther Genetic Tests for Lipid Disorders
ComparisonLIPI Gene Hypertriglyceridemia, susceptibility to NGS Genetic Test

Frequently Asked Questions

What is the LIPI gene and its role in hypertriglyceridemia?
The LIPI gene regulates lipid metabolism; variants can disrupt this process, leading to elevated triglyceride levels and increased risk of hypertriglyceridemia.
How does the NGS genetic test work?
The test uses next-generation sequencing to analyze DNA from blood or extracted samples, identifying genetic variants in 67 genes associated with lipid metabolism, including LIPI.
Who should consider this genetic test?
Individuals with family history of hypertriglyceridemia, personal history of high triglycerides, symptoms like abdominal pain, or those seeking preventive genetic screening.
Is fasting required for this test?
No, fasting is not required for the NGS genetic test, as it analyzes genetic material, not current triglyceride levels.
What does a positive result mean?
A positive result indicates genetic susceptibility to hypertriglyceridemia, meaning higher risk; it does not diagnose the condition but guides monitoring and prevention.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings across many cities in India.
What is the cost of this test?
The test costs INR 20,000, which includes sample collection, NGS analysis, and a clinical report.
Is the test covered by insurance?
Coverage varies; it is not typically covered under standard schemes like PMJAY or CGHS. Check with your insurance provider.
How accurate is the NGS genetic test?
NGS technology is highly accurate for detecting genetic variants, but results should be interpreted clinically, as not all variants may be identified.
Can children undergo this test?
Yes, the test is suitable for all ages, but genetic counseling is recommended to discuss implications for minors.
What should I do after receiving results?
Consult a genetic counselor or healthcare provider to understand results, discuss risk management, and consider lifestyle or medical interventions.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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