Skip to main content
DNA Labs India

Maturity-Onset Diabetes of the Young (MODY) Gene Panel Test

DNA Labs India | ISO 9001:2015 Certified

Maturity-Onset Diabetes of the Young (MODY) Gene Panel Test

Short Name: MODY Gene Panel

Also known as: MODY Panel, MODY Genetic Test, Monogenic Diabetes Panel

Maturity-Onset Diabetes of the Young (MODY) Gene Panel Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Peripheral blood, Amniotic fluid, Chorionic villi samples. Results in 30 Working Days. Free home collection in 300+ cities across India.

Genetic🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

The purpose of the MODY Gene Panel is to confirm or rule out a diagnosis of MODY in individuals with clinical suspicion, especially those with early-onset diabetes, a family history of diabetes in multiple generations, and absence of autoantibodies or insulin resistance. It also helps in differentiating MODY from type 1 and type 2 diabetes, guiding treatment decisions, and enabling predictive testing for family members.

Test Code
6128
CPT Code
81405
ICD Code
E11.9
Price
₹20,000
Sample Type
Peripheral blood, Amniotic fluid, Chorionic villi
Result Time
30 Working Days
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

No special preparation is required. However, a doctor's prescription is mandatory. Inform your physician about any medications you are taking, as some may affect glucose levels but not the genetic test.

Method: Venipuncture / Amniocentesis / CVS

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in your arm. For prenatal testing, amniotic fluid or chorionic villi will be collected by a specialist.

Step 3

Report Delivery

You can resume normal activities immediately. There are no restrictions after blood collection. For prenatal procedures, follow your doctor's advice.

Timeline: 30 Working Days

Patient Instructions

1
Before the Test:No special preparation. Ensure you have a doctor's prescription. Inform the lab if you are pregnant or planning travel abroad, as prescription may not be required in those cases.
2
During the Test:A simple blood draw is performed. For prenatal testing, a specialist will perform the procedure.
3
After the Test:You can resume normal activities. Results will be available in 30 working days.

About This Test

Who Should Get This Test

The purpose of the MODY Gene Panel is to confirm or rule out a diagnosis of MODY in individuals with clinical suspicion, especially those with early-onset diabetes, a family history of diabetes in multiple generations, and absence of autoantibodies or insulin resistance. It also helps in differentiating MODY from type 1 and type 2 diabetes, guiding treatment decisions, and enabling predictive testing for family members.

How to Prepare

  • For blood: Use EDTA vacutainer, mix gently to prevent clotting
  • For amniotic fluid: Collect in sterile container, avoid contamination
  • For CVS: Collect in sterile normal saline container
  • Transport samples at cool pack (2-8°C) to the laboratory

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"MODY is often misdiagnosed as type 1 or type 2 diabetes. Genetic testing is essential for accurate diagnosis, guiding treatment and family screening."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypePeripheral blood, Amniotic fluid, Chorionic villi
Sample Volume3-5 ml blood / 10 ml amniotic fluid / 10 mg CVS
ContainerEDTA Vacutainer / Sterile container / Sterile Normal Saline
Collection MethodVenipuncture / Amniocentesis / CVS

Sample Stability

Blood: 24 hours at 2-8°C, 7 days at room temperature
Amniotic fluid: 48 hours at 2-8°C
CVS: 24 hours at 2-8°C
Sample Rejection Criteria:
  • Hemolyzed or clotted blood sample
  • Incorrect container or labeling
  • Sample received after prolonged transit time (>7 days)
  • Insufficient sample volume

Understanding Your Results

The MODY Gene Panel report will indicate whether any pathogenic or likely pathogenic variants were identified in the analyzed genes. Results are interpreted by clinical geneticists and reported with clear clinical significance.
📊

Positive for pathogenic variant

Confirms diagnosis of MODY. Genetic counseling recommended. Treatment may be tailored based on the specific gene (e.g., sulfonylureas for HNF1A/HNF4A).

📊

Negative for pathogenic variants

No mutation found in the tested genes. MODY is less likely, but other genetic or acquired causes should be considered.

📊

Variant of uncertain significance (VUS)

A genetic change was found, but its clinical significance is unknown. Further family studies may help clarify.

⚠️ When to Consult a Doctor:

If you have a family history of early-onset diabetes, or if you or your child have been diagnosed with diabetes under age 25 without typical type 1 or type 2 features, consult an endocrinologist or geneticist for evaluation and possible testing.

Limitations

  • ⚠This panel does not detect all possible MODY-causing genes; rare genes may not be included
  • ⚠Negative result does not completely exclude MODY; other genetic causes may exist
  • ⚠Variant interpretation may require additional family studies
  • ⚠Not intended for newborn screening or population screening

Risks & Considerations

  • ●Minimal risk of bruising or infection at blood draw site
  • ●For prenatal procedures, small risk of miscarriage or infection (discuss with your doctor)

Interfering Factors

  • ●Contamination of sample with maternal cells in prenatal testing
  • ●Insufficient DNA quantity or quality
  • ●Presence of large deletions/duplications not detected by standard NGS
  • ●Variants of uncertain significance (VUS) may require further analysis

Compare With Similar Tests

TestMaturity-Onset Diabetes of the Young (MODY) Gene Panel
ComparisonMaturity-Onset Diabetes of the Young (MODY) Gene Panel

Frequently Asked Questions

What is MODY?
MODY is a rare monogenic form of diabetes caused by mutations in specific genes. It often presents before age 25 and is not autoimmune or insulin-resistant.
How is MODY different from type 1 and type 2 diabetes?
MODY is inherited in an autosomal dominant pattern, lacks autoantibodies, and is not typically associated with obesity or insulin resistance. It often responds to oral sulfonylureas.
What genes are included in the MODY panel?
The panel includes GCK, HNF1A, HNF4A, PDX1, INS, ABCC8, KCNJ11, and other MODY-associated genes.
Who should get the MODY gene panel?
Individuals with early-onset diabetes (<25 years), family history of diabetes in multiple generations, negative autoantibodies, and no typical type 2 features.
What is the cost of the MODY gene panel in India?
The cost is approximately INR 20,000 at DNA Labs India, with free home sample collection in many cities.
Is fasting required for the test?
No, fasting is not required for the genetic test.
What sample is needed?
A blood sample (EDTA) is usually sufficient. For prenatal testing, amniotic fluid or chorionic villi may be used.
How long does it take to get results?
Results are typically available in 30 working days.
Can MODY be treated?
Yes, treatment depends on the gene mutation. For example, HNF1A/HNF4A MODY responds well to sulfonylureas, while GCK MODY may not require treatment.
Is genetic counseling included?
Yes, DNA Labs India provides genetic counseling as part of the test service.
Is the test covered by insurance?
Insurance coverage varies; it is recommended to check with your provider.
Can the test be done during pregnancy?
Yes, prenatal testing is available using amniotic fluid or CVS, but a doctor's prescription is required.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

Nx Gen Sequencing: Maturity Onset Diabetes of Young (MODY) Test

₹20,000

PDX1 Gene Maturity-onset diabetes of the young type 4 NGS Genetic Test

₹20,000

IGF2 Gene Diabetes, IGF2 related NGS Genetic Test

₹20,000

Nx Gen Sequencing: Maturity Onset Diabetes of Young (MODY) Test

₹20,000

ABCC8 Gene Diabetes mellitus, transient neonatal type 2 NGS Genetic Test

₹20,000

HNF4A Gene Maturity-onset diabetes of the young type 1 NGS Genetic Test

₹20,000
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.