MeDIP Sequencing Data Analysis Test
Short Name: MeDIP Seq Analysis
Also known as: Methylated DNA Immunoprecipitation Sequencing, MeDIP-seq
MeDIP Sequencing Data Analysis Test test available at DNA Labs India for ₹18,000. Uses MeDIP-seq, Next-Generation Sequencing on Extracted DNA samples. Results in Reports are typically available within 4 weeks after the sample reaches the laboratory.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of MeDIP sequencing data analysis is to detect and quantify DNA methylation patterns across the genome. This helps in identifying epigenetic alterations that may contribute to disease pathogenesis. It is particularly useful for cancer research, where aberrant methylation of tumor suppressor genes or oncogenes can be identified. It also aids in diagnosing imprinting disorders, understanding neurodevelopmental conditions, and evaluating autoimmune disease susceptibility. By providing a comprehensive methylation profile, this test supports clinicians in making informed decisions about patient management and treatment strategies.
- Test Code
- 6401
- CPT Code
- 81479
- ICD Code
- Z13.89
- Price
- ₹18,000
- Sample Type
- Extracted DNA
- Result Time
- Reports are typically available within 4 weeks after the sample reaches the laboratory.
- Fasting Required
- No
- Method
- MeDIP-seq, Next-Generation Sequencing
Sample Collection
No special preparation is required. However, inform your healthcare provider about any medications or supplements you are taking.
Method: Blood or saliva sample (for DNA extraction)
Laboratory Analysis
A blood sample or saliva sample will be collected by a trained phlebotomist. The procedure is quick and minimally invasive.
Report Delivery
You can resume normal activities immediately. No restrictions are necessary.
Timeline: Reports are typically available within 4 weeks after the sample reaches the laboratory.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of MeDIP sequencing data analysis is to detect and quantify DNA methylation patterns across the genome. This helps in identifying epigenetic alterations that may contribute to disease pathogenesis. It is particularly useful for cancer research, where aberrant methylation of tumor suppressor genes or oncogenes can be identified. It also aids in diagnosing imprinting disorders, understanding neurodevelopmental conditions, and evaluating autoimmune disease susceptibility. By providing a comprehensive methylation profile, this test supports clinicians in making informed decisions about patient management and treatment strategies.
How to Prepare
- Ensure the sample is collected in a sterile container
- Label the container with patient ID and date
- Transport the sample to the lab within 24 hours if not processed immediately
- Maintain sample at 2-8°C during transport
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"MeDIP sequencing provides critical epigenetic information that complements genetic testing, aiding in early diagnosis and personalized treatment strategies."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed blood samples
- Insufficient DNA quantity (<500 ng)
- DNA with high degradation (DIN <5)
- Improper labeling or missing patient information
Understanding Your Results
Normal methylation pattern
No significant epigenetic alterations detected; further genetic testing may be considered if clinical suspicion remains.
Hypermethylation at tumor suppressor gene promoter
May indicate increased cancer risk or presence of malignancy; correlate with clinical and histopathological findings.
Hypomethylation at oncogene promoter
May lead to gene overexpression and contribute to tumorigenesis; further evaluation recommended.
Loss of imprinting
Suggests imprinting disorder; genetic counseling and confirmatory testing advised.
Differentially methylated regions in autoimmune-related genes
May be associated with autoimmune disease susceptibility; clinical correlation required.
Consult your referring physician or a genetic counselor to discuss the results and their implications for your health. They can help you understand the findings and plan appropriate next steps.
Limitations
- ⚠Cannot distinguish between 5-methylcytosine and 5-hydroxymethylcytosine
- ⚠Requires high-quality DNA; degraded samples may yield unreliable results
- ⚠Data interpretation may be complex and requires expert bioinformatics analysis
- ⚠Not a diagnostic test for a specific disease; results must be correlated with clinical findings
Risks & Considerations
- ●Minimal risk of bruising or infection at the blood draw site
- ●No significant risks associated with saliva collection
Interfering Factors
- ●Poor DNA quality or degradation
- ●Incomplete fragmentation of DNA
- ●Insufficient antibody binding
- ●Low sequencing depth
- ●Contamination with non-methylated DNA
Compare With Similar Tests
| Test | MeDIP Sequencing Data Analysis | ||||
|---|---|---|---|---|---|
| Comparison | MeDIP Sequencing Data Analysis |
Frequently Asked Questions
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
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