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MEIS2 Gene Cleft palate, cardiac defects, and mental retardation NGS Genetic Test

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MEIS2 Gene Cleft palate, cardiac defects, and mental retardation NGS Genetic Test

Short Name: MEIS2 Gene NGS Test

Also known as: MEIS2 Gene Analysis, NGS for MEIS2, MEIS2 Mutation Test

MEIS2 Gene Cleft palate, cardiac defects, and mental retardation NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

PediatricsPediatric🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify mutations in the MEIS2 gene for diagnosis of associated developmental disorders, facilitating early intervention and genetic counseling.

Test Code
5720
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

No special preparation required. Provide clinical history and undergo genetic counseling session to draw a pedigree chart.

Method: Venipuncture

Step 2

Laboratory Analysis

Blood sample will be drawn by a trained phlebotomist using sterile equipment.

Step 3

Report Delivery

Apply pressure to the puncture site to stop bleeding. Resume normal activities immediately.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling session recommended to understand test implications and draw a family pedigree chart.
2
During the Test:Sample collection via blood draw, followed by laboratory analysis using NGS technology.
3
After the Test:Review results with a genetic counselor or healthcare provider to discuss management and next steps.

About This Test

Who Should Get This Test

To identify mutations in the MEIS2 gene for diagnosis of associated developmental disorders, facilitating early intervention and genetic counseling.

How to Prepare

  • Ensure proper patient identification
  • Use sterile collection tubes
  • Label sample correctly with patient details

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early genetic testing for MEIS2 mutations can guide management and family planning, especially in prenatal or pediatric cases."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume3-5 ml of blood
ContainerEDTA tube
Collection MethodVenipuncture

Sample Stability

Blood sample stable for 48 hours at room temperature
Extracted DNA stable for longer periods when stored properly
Sample Rejection Criteria:
  • Hemolyzed sample
  • Insufficient volume
  • Improper labeling or contamination

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the MEIS2 gene, which can be associated with developmental disorders.
Positive: Mutation detected, indicating association with MEIS2-related conditions
Negative: No mutation detected, but clinical symptoms may require further testing
Variant of uncertain significance: Requires additional analysis and clinical correlation
⚠️ When to Consult a Doctor:

If symptoms such as cleft palate, cardiac issues, developmental delays, or intellectual disability are present, consult a genetic counselor or healthcare provider for evaluation and management.

Limitations

  • ⚠May not detect all types of mutations
  • ⚠Results require clinical correlation
  • ⚠Not a diagnostic tool for all genetic disorders

Risks & Considerations

  • ●Minimal risk from blood draw: bruising, infection, or discomfort
  • ●Psychological impact of results may require support

Interfering Factors

  • ●Contaminated DNA sample
  • ●Insufficient sample volume
  • ●Hemolyzed blood sample

Compare With Similar Tests

TestMEIS2 Gene Cleft palate, cardiac defects, and mental retardation NGS Genetic TestWhole Exome SequencingChromosomal Microarray AnalysisFISH for 22q11.2 Deletion SyndromeSingle Gene Disorder Panel
ComparisonMEIS2 Gene Cleft palate, cardiac defects, and mental retardation NGS Genetic Test

Frequently Asked Questions

What is the MEIS2 Gene NGS Genetic Test?
It is a genetic test that uses Next-Generation Sequencing to identify mutations in the MEIS2 gene, associated with cleft palate, cardiac defects, and mental retardation.
Why is this test recommended?
It is recommended for individuals with symptoms like cleft palate, heart defects, developmental delays, or intellectual disability to diagnose MEIS2-related disorders.
How is the test performed?
A blood sample is collected and analyzed in the laboratory using NGS technology to detect mutations in the MEIS2 gene.
What are the symptoms that indicate the need for this test?
Symptoms include cleft palate, cardiac defects, developmental delay, intellectual disability, facial abnormalities, seizures, and feeding difficulties.
How long does it take to get the results?
Results are typically available within 3 to 4 weeks after sample collection.
What does a positive result mean?
A positive result indicates a mutation in the MEIS2 gene, which may be associated with developmental disorders, requiring further medical management.
Is the test covered by insurance?
Coverage varies; it is not typically covered by government schemes like PMJAY, but private insurance may cover it depending on the policy.
Can the test be done at home?
Yes, DNA Labs India offers free home sample collection for this test across many cities in India.
What is the cost of the test?
The test costs INR 20000, with possible discounts available for online bookings.
Who should consider taking this test?
Children or individuals with symptoms of MEIS2-related disorders, or families with a history of such conditions, should consider this test.
How accurate is the NGS technology for this test?
NGS is highly accurate for detecting genetic mutations, but results should be interpreted in conjunction with clinical findings.
What are the next steps after receiving the results?
Consult a genetic counselor or healthcare provider to discuss results, management options, and potential genetic counseling for family planning.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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