Mitotane Test
Also known as: MITOTANE Blood Test, Mitotane Level Test
Mitotane Test test available at DNA Labs India for ₹15,000. Uses Gas Chromatography on Serum samples. Results in 2-3 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the Mitotane Test is to measure the blood level of MITOTANE to monitor its therapeutic effect in treating adrenal cortical carcinoma, ensure optimal dosing, and prevent potential toxicity.
- Test Code
- 1253
- Price
- ₹15,000
- Sample Type
- Serum
- Result Time
- 2-3 weeks
- Fasting Required
- No
- Method
- Gas Chromatography
Sample Collection
No specific preparation required. Inform your doctor about all medications you are taking.
Method: Venipuncture
Laboratory Analysis
A healthcare professional will draw blood from a vein in your arm using standard phlebotomy techniques.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. You can resume normal activities immediately.
Timeline: 2-3 weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Mitotane Test is to measure the blood level of MITOTANE to monitor its therapeutic effect in treating adrenal cortical carcinoma, ensure optimal dosing, and prevent potential toxicity.
How to Prepare
- Collect blood in a serum separator tube (SST).
- Label the sample with patient details and test name.
- Transport to the laboratory at room temperature within specified stability period.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"Monitoring MITOTANE levels is essential for optimizing treatment efficacy and minimizing toxicity in patients with adrenal cortical carcinoma."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or lipemic samples.
- Incorrect sample type or container.
- Samples collected beyond stability period.
Understanding Your Results
May indicate subtherapeutic dosing, poor compliance, or rapid metabolism. Consult physician for dosage adjustment.
Level: Below Therapeutic Range (e.g., <10 μg/mL)
Suggests adequate drug levels for treatment efficacy. Continue monitoring as advised.
Level: Within Therapeutic Range (e.g., 10-20 μg/mL)
May indicate risk of toxicity, such as gastrointestinal or neurological symptoms. Immediate medical review recommended.
Level: Above Therapeutic Range (e.g., >20 μg/mL)
Consult your doctor if you experience symptoms of MITOTANE toxicity (e.g., nausea, dizziness, confusion), if your test results are outside the therapeutic range, or if symptoms of adrenal cancer persist or worsen.
Limitations
- ⚠This test measures MITOTANE concentration but does not directly diagnose cancer or assess tumor response.
- ⚠Results should be correlated with clinical symptoms, imaging, and other laboratory tests.
- ⚠Reference ranges may vary between laboratories and individuals.
Risks & Considerations
- ●Minor pain or bruising at the blood draw site.
- ●Rare risk of infection or excessive bleeding.
- ●No significant risks associated with the test itself.
Interfering Factors
- ●Concomitant use of other medications that affect hepatic metabolism.
- ●Hepatic or renal impairment may alter MITOTANE clearance.
- ●Sample hemolysis or improper storage can affect accuracy.
Compare With Similar Tests
| Test | Mitotane Test | Cortisol Test | ACTH Test | CT Scan Abdomen | Biopsy Adrenal |
|---|---|---|---|---|---|
| Comparison | Mitotane Test | Measures cortisol levels to assess adrenal function, often used alongside MITOTANE monitoring. | Evaluates adrenocorticotropic hormone levels, helpful in diagnosing adrenal disorders. | Imaging test to visualize adrenal tumors, complementary to laboratory monitoring. | Invasive procedure for histological diagnosis of adrenal cancer, not a routine monitoring test. |
Frequently Asked Questions
What is MITOTANE?
Why is the Mitotane Test done?
How is the Mitotane Test performed?
What do the results mean?
Are there any risks to the test?
How long does it take to get results?
What is the cost of the Mitotane Test?
Is home collection available for this test?
Do I need to fast before the Mitotane Test?
What if my MITOTANE levels are too high or low?
Can this test diagnose adrenal cancer?
How often should the Mitotane Test be done?
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