MT-TF Gene MELAS syndrome NGS Genetic Test
Short Name: MT-TF MELAS NGS Test
Also known as: MELAS Syndrome Genetic Test, MT-TF Gene Test, Mitochondrial Encephalomyopathy Test
MT-TF Gene MELAS syndrome NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To diagnose MELAS syndrome by detecting pathogenic mutations in the MT-TF gene using Next Generation Sequencing (NGS) technology, aiding in clinical management and genetic counseling.
- Test Code
- 2537
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- NGS Technology
Sample Collection
Clinical history of the patient and a genetic counseling session to draw a pedigree chart of family members affected with MELAS syndrome.
Method: Venipuncture
Laboratory Analysis
Standard blood draw procedure.
Report Delivery
Sample is processed for NGS analysis in the laboratory.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
To diagnose MELAS syndrome by detecting pathogenic mutations in the MT-TF gene using Next Generation Sequencing (NGS) technology, aiding in clinical management and genetic counseling.
How to Prepare
- Ensure proper sample labeling
- Use sterile collection tubes
- Follow aseptic techniques
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early genetic testing for MELAS syndrome can guide treatment, manage symptoms, and inform family planning decisions."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed samples
- Insufficient sample volume
- Improper labeling
Understanding Your Results
Positive
Pathogenic variant detected, consistent with MELAS syndrome
Negative
No pathogenic variants detected; clinical correlation recommended
Variant of Uncertain Significance
Genetic variant found but significance unclear; further testing may be needed
If symptoms of MELAS syndrome are present, such as recurrent headaches, seizures, or stroke-like episodes, or if there is a family history of mitochondrial disorders.
Limitations
- ⚠May not detect all genetic variants
- ⚠Requires clinical correlation for diagnosis
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection
- ●Potential psychological impact of genetic results
Interfering Factors
- ●Poor sample quality
- ●Contamination during collection
Frequently Asked Questions
What is MELAS syndrome?
What causes MELAS syndrome?
What are the common symptoms of MELAS syndrome?
How is MELAS syndrome diagnosed?
What is the MT-TF gene?
What is NGS genetic testing?
How much does the MT-TF Gene MELAS Syndrome NGS Genetic Test cost?
Is home sample collection available for this test?
How long does it take to get results?
What should I do before the test?
Can this test be used for family planning?
Is the test covered by insurance?
Related Tests
Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.