MT-TL1 Gene MELAS syndrome, MT-TL1 related NGS Genetic Test
Short Name: MT-TL1 MELAS Genetic Test
Also known as: MELAS Syndrome Genetic Test, MT-TL1 Mutation Analysis, Mitochondrial DNA Testing
MT-TL1 Gene MELAS syndrome, MT-TL1 related NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3-4 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To identify mutations in the MT-TL1 gene for diagnosis of MELAS syndrome and related mitochondrial disorders, enabling early intervention and personalized management.
- Test Code
- 2155
- ICD Code
- G71.3
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3-4 weeks
- Fasting Required
- No
- Method
- NGS Technology
Sample Collection
No special preparation required. Provide clinical history and family pedigree during genetic counseling.
Method: Venipuncture or Dried Blood Spot
Laboratory Analysis
Blood sample will be collected via venipuncture or a dried blood spot on FTA card by a trained phlebotomist.
Report Delivery
Apply pressure to the puncture site to stop bleeding. Follow any specific instructions from the collection center.
Timeline: 3-4 weeks
Patient Instructions
About This Test
Who Should Get This Test
To identify mutations in the MT-TL1 gene for diagnosis of MELAS syndrome and related mitochondrial disorders, enabling early intervention and personalized management.
How to Prepare
- Ensure proper sample labeling
- Maintain ambient room temperature during transport
- Use provided containers for sample stability
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early genetic testing for MT-TL1 mutations is crucial for managing MELAS syndrome and improving patient outcomes through tailored treatment plans."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed sample
- Insufficient volume
- Incorrect sample type
Understanding Your Results
Positive
Pathogenic variant detected in MT-TL1 gene, consistent with MELAS syndrome. Further clinical evaluation and management recommended.
Negative
No pathogenic variant detected. Clinical correlation advised if symptoms persist, as other genetic or metabolic causes may be involved.
If experiencing symptoms such as seizures, stroke-like episodes, or muscle weakness, or if there is a family history of mitochondrial disorders.
Limitations
- ⚠May not detect all mutations
- ⚠Requires genetic counseling for interpretation
- ⚠Results should be correlated with clinical findings
Risks & Considerations
- ●Bruising at puncture site
- ●Rare infection risk
- ●Minimal discomfort during blood draw
Interfering Factors
- ●Sample contamination
- ●Degraded DNA
- ●Improper sample handling
Frequently Asked Questions
What is MT-TL1 Gene MELAS syndrome?
How is MELAS syndrome diagnosed?
What is the cost of the MT-TL1 related NGS genetic test in India?
Is the genetic test covered by insurance?
What sample type is required for the test?
How long does it take to get results?
Is home sample collection available?
What are the symptoms of MELAS syndrome?
Can MELAS syndrome be treated?
Who should consider this genetic test?
What is the method used for this test?
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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