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MYO15A Gene Deafness, autosomal recessive type 3 NGS Genetic Test

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MYO15A Gene Deafness, autosomal recessive type 3 NGS Genetic Test

Short Name: MYO15A Genetic Test

Also known as: DFNB3, MYO15A-related hearing loss

MYO15A Gene Deafness, autosomal recessive type 3 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify mutations in the MYO15A gene responsible for autosomal recessive deafness type 3, aiding in diagnosis, management, and genetic counseling.

Test Code
2335
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

No specific preparation required. Provide clinical history and undergo genetic counseling.

Method: Venipuncture or fingerstick

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or fingerstick for FTA card.

Step 3

Report Delivery

Apply pressure to the puncture site. Store sample as instructed.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling session to draw a pedigree chart of family members affected with deafness. Provide clinical history.
2
During the Test:Sample collection of blood or DNA. No discomfort beyond a standard blood draw.
3
After the Test:Await results in 3-4 weeks. Discuss findings with a genetic counselor or doctor.

About This Test

Who Should Get This Test

To identify mutations in the MYO15A gene responsible for autosomal recessive deafness type 3, aiding in diagnosis, management, and genetic counseling.

How to Prepare

  • Use EDTA tube for blood or FTA card for one drop blood
  • Label sample with patient details
  • Transport at ambient room temperature

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for MYO15A is crucial for diagnosing autosomal recessive deafness type 3, enabling targeted management and family counseling."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume5 mL blood
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or fingerstick

Sample Stability

Blood: Stable at room temperature for 24 hours
FTA card: Stable for extended periods at room temperature
Sample Rejection Criteria:
  • Hemolyzed or clotted blood sample
  • Insufficient sample volume
  • Improper labeling or storage

Understanding Your Results

Results indicate presence or absence of mutations in the MYO15A gene. A positive result confirms genetic basis for deafness, while negative suggests other causes.
Positive: Pathogenic mutations detected – indicates autosomal recessive deafness type 3
Negative: No mutations found – deafness may have non-genetic or other genetic causes
Variant of uncertain significance (VUS) – requires further evaluation
⚠️ When to Consult a Doctor:

Consult an ENT specialist or geneticist if you have persistent hearing loss, family history of deafness, or after receiving test results for management guidance.

Limitations

  • ⚠May not detect all genetic variants or large deletions
  • ⚠Results require clinical correlation and genetic counseling
  • ⚠Not a standalone diagnostic for all causes of deafness

Risks & Considerations

  • ●Minimal risks from blood draw: bruising, infection at puncture site

Interfering Factors

  • ●Contaminated or degraded DNA sample
  • ●Insufficient sample volume
  • ●Technical errors during NGS processing

Compare With Similar Tests

TestMYO15A Gene Deafness, autosomal recessive type 3 NGS Genetic TestGJB2 Gene TestSLC26A4 Gene TestTECTA Gene TestComprehensive Deafness Panel
ComparisonMYO15A Gene Deafness, autosomal recessive type 3 NGS Genetic Test

Frequently Asked Questions

What is the MYO15A gene deafness test?
It is an NGS genetic test that identifies mutations in the MYO15A gene, causing autosomal recessive deafness type 3.
How much does the test cost?
The test costs INR 20,000, with free home sample collection available across India.
What samples are required?
Blood, extracted DNA, or one drop blood on an FTA card.
Is fasting required?
No, fasting is not required for this test.
How long does it take to get results?
Results are typically available in 3 to 4 weeks.
Is the test covered by insurance?
This test is typically not covered by insurance. Check with your provider for specific coverage.
What are the symptoms of MYO15A gene deafness?
Symptoms include difficulty hearing in noise, trouble understanding speech, frequent ear infections, tinnitus, and balance problems.
Who should consider this test?
Individuals with unexplained hearing loss, family history of deafness, or symptoms suggestive of genetic deafness.
What does a positive result mean?
A positive result confirms mutations in the MYO15A gene, indicating genetic deafness. Genetic counseling is recommended.
Are there any risks?
Risks are minimal, similar to a standard blood draw, such as bruising or infection.
Can this test be done at home?
Yes, DNA Labs India offers free home sample collection in many cities across India.
What should I do before getting tested?
Undergo a genetic counseling session to discuss family history and understand the test implications.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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