NKX2-2 Gene Maturity-onset diabetes of the young, NKX2-2 related NGS Genetic Test
Short Name: NKX2-2 MODY NGS Test
Also known as: MODY Type 7 Genetic Test, NKX2-2 Sequencing Test, NKX2-2 Gene Diabetes Test
NKX2-2 Gene Maturity-onset diabetes of the young, NKX2-2 related NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To detect pathogenic variants in the NKX2-2 gene and other MODY-related genes for accurate diagnosis of maturity-onset diabetes of the young type 7, guiding treatment decisions and genetic counseling.
- Test Code
- 2146
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Obtain detailed clinical and family history. Ensure genetic counseling session is scheduled prior to testing.
Method: Venipuncture or FTA Card application
Laboratory Analysis
Sample collected via venipuncture for blood or application of FTA card for one-drop blood, following standard aseptic techniques.
Report Delivery
Label sample correctly and transport to lab under ambient temperature conditions as specified.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
To detect pathogenic variants in the NKX2-2 gene and other MODY-related genes for accurate diagnosis of maturity-onset diabetes of the young type 7, guiding treatment decisions and genetic counseling.
How to Prepare
- Provide clinical history of the patient
- Complete a genetic counseling session to draw a family pedigree chart
- Ensure sample is collected in appropriate container and stored properly
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic testing like the NKX2-2 NGS test is essential for distinguishing MODY from other diabetes types, ensuring targeted treatment and family counseling."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Insufficient sample volume
- Incorrect sample labeling
- Sample stored outside stability parameters
Understanding Your Results
Consult a doctor or genetic counselor if test results are positive, if there is a family history of MODY, or if symptoms persist despite negative results for further evaluation.
Limitations
- ⚠May not detect all possible genetic variants due to sequencing technology limits
- ⚠Results require interpretation by a genetic counselor or physician
- ⚠Not suitable for diagnosing other forms of diabetes without additional tests
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection at the puncture site
- ●Potential psychological impact of genetic results; counseling advised
Interfering Factors
- ●Sample contamination during collection
- ●Degradation of DNA in improper storage
- ●Recent blood transfusions affecting DNA
- ●Use of certain medications impacting sample quality
Compare With Similar Tests
| Test | NKX2-2 Gene Maturity-onset diabetes of the young, NKX2-2 related NGS Genetic Test | HbA1c Test | Glucose Tolerance Test | Other MODY Gene Panels | Insulin Level Test |
|---|---|---|---|---|---|
| Comparison | NKX2-2 Gene Maturity-onset diabetes of the young, NKX2-2 related NGS Genetic Test | Measures average blood sugar over time; not specific for genetic causes like MODY. | Assesses glucose metabolism; does not identify genetic mutations. | Tests multiple genes; may include NKX2-2 but with different sequencing depth. | Evaluates insulin secretion; not diagnostic for specific genetic mutations. |
Frequently Asked Questions
What is the NKX2-2 gene?
What is Maturity-onset diabetes of the young (MODY)?
How is NKX2-2 related MODY diagnosed?
What are the symptoms of NKX2-2 related MODY?
Who should consider this genetic test?
What is the cost of the NKX2-2 NGS Genetic Test?
Is home sample collection available?
How long does it take to get results?
What samples are required for the test?
Is genetic counseling necessary?
Can this test detect all MODY types?
What should I do after receiving test results?
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₹20,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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