Oxcarbazepine Metabolite Test
Short Name: Oxcarbazepine Metabolite
Also known as: Oxcarbazepine TDM, 10-OH-carbazepine Test, Trileptal Metabolite Test
Oxcarbazepine Metabolite Test test available at DNA Labs India for ₹6,500. Uses LC-MS/MS on Serum samples. Results in Sample Mon through Sat by 5 pm; Report 10 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Ramarao Paidisetty
Consultant Biochemist · Reg: 21504
Last reviewed: September 7, 2026
Overview
The Oxcarbazepine Metabolite Test is used to measure the level of the active metabolite 10-OH-carbazepine in the blood. This helps clinicians determine the appropriate dosage of oxcarbazepine and monitor the effectiveness of treatment in patients with epilepsy.
- Test Code
- 3522
- Price
- ₹6,500
- Sample Type
- Serum
- Result Time
- Sample Mon through Sat by 5 pm; Report 10 days
- Fasting Required
- No
- Method
- LC-MS/MS
Sample Collection
Collect the sample just before the next dose is due at steady state. Inform the healthcare provider about all medications being taken.
Method: Venipuncture
Laboratory Analysis
A small blood sample is drawn from a vein using a plain Red Top tube. Do not use SST gel barrier tubes.
Report Delivery
No special post-collection restrictions are usually required. Keep the puncture site clean and dry.
Timeline: Sample Mon through Sat by 5 pm; Report 10 days
Patient Instructions
About This Test
Who Should Get This Test
The Oxcarbazepine Metabolite Test is used to measure the level of the active metabolite 10-OH-carbazepine in the blood. This helps clinicians determine the appropriate dosage of oxcarbazepine and monitor the effectiveness of treatment in patients with epilepsy.
How to Prepare
- Recommended specimen: just before the next dose is due at steady state.
- Use a plain Red Top (No Additive) tube.
- Do not use SST gel barrier tubes.
- Ship refrigerated or frozen.
Doctor's Notes
Reviewed by Dr Ramarao Paidisetty — MBBS, MD (Biochemistry) · Reg. No. 21504
"Therapeutic drug monitoring of oxcarbazepine helps tailor anti-epileptic dosing to maintain seizure control while minimising toxicity. The active metabolite 10-OH-carbazepine should be measured at trough steady-state concentrations."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample collected in SST gel barrier tube
- Insufficient sample volume (<1 mL)
- Grossly haemolysed sample
- Improper transport temperature
Understanding Your Results
Subtherapeutic level; may increase seizure risk. Dose adjustment may be required.
Therapeutic range for most patients.
Toxic level; may cause adverse effects. Urgent clinical review is required.
Consult the treating neurologist if you experience breakthrough seizures, unusual drowsiness, dizziness, double vision, nausea, or other signs of possible toxicity or treatment failure.
Limitations
- ⚠Requires steady-state trough collection for accurate interpretation.
- ⚠Does not measure parent oxcarbazepine alone.
- ⚠Clinical correlation with patient symptoms is essential.
Risks & Considerations
- ●Bleeding at the site of the needle puncture
- ●Infection at the site of the needle puncture
- ●Feeling lightheaded or fainting
Interfering Factors
- ●Use of SST gel barrier tubes may interfere with the assay.
- ●Improper storage or transport temperature may affect results.
- ●Non-steady-state sampling may not reflect true trough levels.
Compare With Similar Tests
| Test | Oxcarbazepine Metabolite Test | Carbamazepine Metabolite Test | Valproic Acid Test |
|---|---|---|---|
| Comparison | Oxcarbazepine Metabolite Test |
Frequently Asked Questions
What is the Oxcarbazepine Metabolite Test?
Why is the Oxcarbazepine Metabolite Test done?
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Is fasting required for this test?
What is the therapeutic range for 10-OH-carbazepine?
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