Oxford Nanopore-Flow Cell Test
Short Name: Oxford Nanopore Flow Cell
Also known as: Nanopore Sequencing, Long-read Sequencing, Flow Cell Sequencing
Oxford Nanopore-Flow Cell Test test available at DNA Labs India for ₹250,000. Uses Oxford Nanopore Sequencing, Long-read DNA Sequencing on Extracted DNA samples. Results in Reports are typically delivered within 2 weeks from sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the Oxford Nanopore Flow Cell test is to sequence DNA with high accuracy and speed to diagnose genetic disorders. It is particularly useful for identifying mutations that cause rare diseases, guiding treatment decisions in oncology, and providing reproductive risk assessment. The long-read capability allows for the detection of large structural variants, repeat expansions, and phasing of alleles, which are often missed by other methods. This test aids in confirming clinical diagnoses, carrier screening, and pharmacogenomic profiling.
- Test Code
- 6447
- CPT Code
- Not Applicable
- ICD Code
- Not Applicable
- Price
- ₹250,000
- Sample Type
- Extracted DNA
- Result Time
- Reports are typically delivered within 2 weeks from sample receipt.
- Fasting Required
- No
- Method
- Oxford Nanopore Sequencing, Long-read DNA Sequencing
Sample Collection
No special preparation required. However, if blood sample is being collected, no fasting is needed. Ensure adequate hydration.
Method: Blood or saliva sample for DNA extraction
Laboratory Analysis
A blood sample (5-10 mL) will be drawn from a vein in your arm. Alternatively, a saliva sample may be collected. The procedure is quick and minimally invasive.
Report Delivery
You can resume normal activities immediately. The sample will be sent to our laboratory for DNA extraction and sequencing.
Timeline: Reports are typically delivered within 2 weeks from sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Oxford Nanopore Flow Cell test is to sequence DNA with high accuracy and speed to diagnose genetic disorders. It is particularly useful for identifying mutations that cause rare diseases, guiding treatment decisions in oncology, and providing reproductive risk assessment. The long-read capability allows for the detection of large structural variants, repeat expansions, and phasing of alleles, which are often missed by other methods. This test aids in confirming clinical diagnoses, carrier screening, and pharmacogenomic profiling.
How to Prepare
- For blood sample: Use EDTA tube, mix gently
- For saliva sample: Use Oragene kit, avoid eating/drinking 30 minutes prior
- Label the sample with patient ID and date
- Store at room temperature if processed within 24 hours, otherwise refrigerate
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"The Oxford Nanopore Flow Cell enables long-read sequencing, which is crucial for detecting structural variants and repeat expansions that are often missed by short-read methods. This technology enhances diagnostic accuracy for complex genetic disorders."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed blood sample
- Clotted blood sample
- Insufficient DNA quantity (<1 µg)
- DNA degraded (OD260/280 <1.8)
- Improper labeling
Understanding Your Results
Positive
Pathogenic variant detected. Clinical correlation and genetic counseling recommended.
Negative
No pathogenic variants found. Further testing may be considered if clinical suspicion remains high.
Variant of Uncertain Significance (VUS)
A variant with unknown clinical significance. Additional family studies or functional assays may be needed.
Consult your physician or genetic counselor if you have a family history of genetic disorders, if you are planning a family, or if you have unexplained symptoms that may have a genetic basis. Early diagnosis can guide treatment and management.
Limitations
- ⚠May not detect all types of mutations (e.g., deep intronic variants)
- ⚠Requires high-quality DNA extraction
- ⚠Interpretation may be limited by incomplete databases
- ⚠Cost may be prohibitive for some patients
- ⚠Not a substitute for clinical diagnosis
Risks & Considerations
- ●Minimal risk of bruising or infection at blood draw site
- ●Psychological impact of genetic results
- ●Potential for incidental findings
Interfering Factors
- ●Low DNA quality or quantity
- ●Contamination with RNA or proteins
- ●Degraded DNA due to improper storage
- ●Presence of PCR inhibitors
- ●Incomplete reference genome alignment
Compare With Similar Tests
| Test | Oxford Nanopore-Flow Cell | Sanger Sequencing | Illumina Short-Read Sequencing | Microarray |
|---|---|---|---|---|
| Comparison | Oxford Nanopore-Flow Cell | Sanger is limited to single genes or small regions, while Oxford Nanopore can sequence entire genomes with long reads. | Illumina offers high accuracy for small variants but misses large structural variants; Oxford Nanopore detects both. | Microarray detects copy number changes but not single nucleotide variants; Oxford Nanopore provides comprehensive variant detection. |
Frequently Asked Questions
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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