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DNA Labs India

PacBio Sequel- 30 GB Test

DNA Labs India | ISO 9001:2015 Certified

PacBio Sequel- 30 GB Test

Short Name: PacBio Sequel 30GB

Also known as: PacBio Long-Read Sequencing, SMRT Sequencing 30GB, Third-Generation Sequencing

PacBio Sequel- 30 GB Test test available at DNA Labs India for ₹510,000. Uses Single Molecule Real-Time (SMRT) Sequencing on Extracted DNA samples. Results in Results are typically available within 4 weeks from the date of sample receipt. In some cases, complex analyses may take longer.. Free home collection in 300+ cities across India.

Next-Generation Sequencing (NGS)🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

The purpose of the PacBio Sequel 30GB test is to provide a complete and accurate picture of an individual's genetic makeup, especially for complex genetic disorders where standard sequencing methods may be insufficient. It helps in identifying disease-causing variants, structural rearrangements, and repeat expansions, thereby aiding in accurate diagnosis, prognosis, and personalized treatment planning.

Test Code
6450
CPT Code
81479
ICD Code
Z01.89
Price
₹510,000
Sample Type
Extracted DNA
Result Time
Results are typically available within 4 weeks from the date of sample receipt. In some cases, complex analyses may take longer.
Fasting Required
No
Method
Single Molecule Real-Time (SMRT) Sequencing
Step 1

Sample Collection

No special preparation is required. However, if providing a blood sample, inform your doctor about any medications you are taking. For saliva samples, avoid eating, drinking, or smoking for 30 minutes before collection.

Method: Blood or saliva sample for DNA extraction

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in your arm, or you may be asked to provide a saliva sample in a sterile container. The procedure is quick and minimally invasive.

Step 3

Report Delivery

You can resume normal activities immediately. The sample will be sent to the laboratory for DNA extraction and sequencing. Results will be available in approximately 4 weeks.

Timeline: Results are typically available within 4 weeks from the date of sample receipt. In some cases, complex analyses may take longer.

Patient Instructions

1
Before the Test:No special preparation is needed. However, ensure you have a valid doctor's prescription if required. Inform the lab about any ongoing treatments or clinical trials.
2
During the Test:The sample collection is simple and painless. For blood, a small amount is drawn; for saliva, you will spit into a tube. The entire process takes about 5-10 minutes.
3
After the Test:You can leave immediately. The lab will process your sample and provide a report in 4 weeks. You may be contacted for additional information if needed.

About This Test

Who Should Get This Test

The purpose of the PacBio Sequel 30GB test is to provide a complete and accurate picture of an individual's genetic makeup, especially for complex genetic disorders where standard sequencing methods may be insufficient. It helps in identifying disease-causing variants, structural rearrangements, and repeat expansions, thereby aiding in accurate diagnosis, prognosis, and personalized treatment planning.

How to Prepare

  • Use a sterile, DNA-free collection tube
  • For blood: collect in EDTA tube and mix gently
  • For saliva: provide 2 mL of saliva in the provided container
  • Label the tube with patient name and date of birth
  • Store at room temperature if shipping within 24 hours, otherwise refrigerate

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Long-read sequencing is essential for resolving complex genomic regions that short-read technologies miss. This test provides a comprehensive view of the genome, aiding in precise diagnosis and targeted therapy."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeExtracted DNA
Sample Volume2-5 µg (concentration ≥ 50 ng/µL)
ContainerDNA LoBind tube
Collection MethodBlood or saliva sample for DNA extraction

Sample Stability

Room temperature (20-25°C)Up to 24 hours
Refrigerated (2-8°C)Up to 7 days
Frozen (-20°C)Up to 1 month
Sample Rejection Criteria:
  • Hemolyzed blood sample
  • Clotted blood sample
  • Insufficient DNA quantity (< 1 µg)
  • DNA with A260/A280 ratio < 1.8 or > 2.0
  • Sample not labeled correctly

Understanding Your Results

The PacBio Sequel 30GB test generates a comprehensive genomic dataset. Interpretation is performed by clinical geneticists and bioinformaticians who analyze the data for clinically relevant variants. Results are reported in the context of the patient's clinical presentation and family history.
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Confirms the diagnosis of the associated genetic disorder. Genetic counseling is recommended.

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Further testing or family studies may be needed to clarify the clinical significance.

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Reduces the likelihood of a genetic cause, but does not exclude all possibilities.

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May explain the phenotype; correlation with clinical features is essential.

⚠️ When to Consult a Doctor:

Consult your referring physician or a genetic counselor to discuss the results and their implications for your health, family planning, and treatment options.

Limitations

  • ⚠High cost compared to short-read sequencing
  • ⚠Requires high-quality, high-molecular-weight DNA
  • ⚠Bioinformatics analysis is complex and time-consuming
  • ⚠May not detect all types of variants (e.g., epigenetic changes)
  • ⚠Not available in all diagnostic centers

Risks & Considerations

  • ●No significant physical risks associated with sample collection
  • ●Possible bruising or discomfort at the blood draw site
  • ●Psychological impact of receiving genetic results

Interfering Factors

  • ●Low DNA quality or quantity
  • ●Contamination with RNA or proteins
  • ●Degraded DNA due to improper storage or transport
  • ●Presence of PCR inhibitors
  • ●Incomplete genome assembly due to repetitive regions

Compare With Similar Tests

TestPacBio Sequel- 30 GBShort-Read Sequencing (e.g., Illumina)Sanger SequencingMicroarray
ComparisonPacBio Sequel- 30 GB

Frequently Asked Questions

What is the cost of the PacBio Sequel 30GB test?
The cost is INR 510000, which includes sample collection, sequencing, bioinformatics analysis, and a comprehensive clinical report.
What is the turnaround time for results?
Results are typically available within 4 weeks from the date of sample receipt.
What type of sample is required?
Extracted DNA is required. We provide a free home sample collection service for blood or saliva samples.
Is fasting required before the test?
No, fasting is not required for this test.
What conditions can this test diagnose?
It can help diagnose rare genetic disorders, certain cancers, and infectious diseases by detecting structural variants, gene fusions, and other complex genetic changes.
How is PacBio different from other sequencing methods?
PacBio uses long-read sequencing, which can read much longer DNA fragments, allowing detection of structural variations and repeat expansions that short-read methods may miss.
Is home sample collection available?
Yes, we offer free home sample collection for online bookings across major cities in India.
Will my insurance cover this test?
Coverage depends on your insurance provider and policy. We recommend checking with your insurer. We also offer assistance with pre-authorization if needed.
Can this test be done during pregnancy?
Yes, but it is important to discuss with your obstetrician or genetic counselor. The test can be performed on a blood sample from the mother (for NIPT) or other appropriate samples.
What is the accuracy of this test?
PacBio sequencing has high accuracy, with consensus accuracy >99.9% for single nucleotide variants. However, no test is 100% accurate, and results should be interpreted by a specialist.
Are there any risks associated with the test?
The test is non-invasive and carries minimal risk. For blood collection, there is a small risk of bruising or infection at the puncture site.
How do I book this test?
You can book online through our website or call our customer care. Our team will schedule a home sample collection at your convenience.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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