PAX9 Gene Tooth agenesis, selective type 3 NGS Genetic Test
Short Name: PAX9 NGS Test
Also known as: PAX9 Gene Mutation Test, Selective Tooth Agenesis Genetic Test, PAX9 Sequencing
PAX9 Gene Tooth agenesis, selective type 3 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Reports are delivered within 3 to 4 weeks after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of this test is to identify mutations in the PAX9 gene that cause selective tooth agenesis type 3. It helps confirm clinical diagnosis, guide dental treatment, assess recurrence risk in families, and enable informed reproductive decisions.
- Test Code
- 5959
- CPT Code
- 81408
- ICD Code
- K00.0
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- Reports are delivered within 3 to 4 weeks after sample receipt.
- Fasting Required
- No
- Method
- Next Generation Sequencing (NGS)
Sample Collection
No special preparation required. Inform your doctor about any medications or supplements. A genetic counseling session is recommended before the test.
Method: Venipuncture or Fingerstick
Laboratory Analysis
A blood sample will be drawn from a vein in your arm, or a fingerstick blood drop will be placed on an FTA card. The procedure is quick and minimally invasive.
Report Delivery
You can resume normal activities immediately. No restrictions.
Timeline: Reports are delivered within 3 to 4 weeks after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to identify mutations in the PAX9 gene that cause selective tooth agenesis type 3. It helps confirm clinical diagnosis, guide dental treatment, assess recurrence risk in families, and enable informed reproductive decisions.
How to Prepare
- For blood sample: Use EDTA vacutainer, fill to indicated mark, mix gently.
- For FTA card: Apply one drop of blood onto the designated circle, air dry for 30 minutes.
- Label the sample with patient name, date, and time of collection.
- Transport at ambient temperature (15-30°C) within 24 hours.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"Genetic testing for PAX9 mutations is essential for accurate diagnosis and family planning. Early detection helps in managing dental health effectively."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed blood sample
- Clotted blood sample (if EDTA not used)
- Insufficient sample volume
- Improper labeling
- Sample received after prolonged transit (>7 days) without proper storage
Understanding Your Results
Positive (pathogenic variant detected)
Confirms diagnosis of PAX9-related tooth agenesis. Genetic counseling recommended for family members.
Negative (no pathogenic variant detected)
No mutation in PAX9 gene found. Other genetic or environmental causes may be considered.
Variant of uncertain significance (VUS)
A genetic change was found, but its clinical significance is unclear. Further testing may be needed.
Consult a dentist or geneticist if you or your child have missing teeth, delayed tooth eruption, or a family history of tooth agenesis. Early evaluation can improve dental outcomes.
Limitations
- ⚠This test detects mutations only in the PAX9 gene; other genes (e.g., MSX1, AXIN2) are not analyzed.
- ⚠Variant of uncertain significance (VUS) may be reported; further family studies may be needed.
- ⚠Large deletions/duplications may not be detected by standard NGS; additional testing may be required.
- ⚠Test does not predict severity or exact number of missing teeth.
Risks & Considerations
- ●Minimal risk of bruising or infection at blood draw site
- ●Psychological impact of genetic results
- ●Potential for incidental findings
Interfering Factors
- ●Poor DNA quality from improper sample handling
- ●Contamination during sample collection
- ●Recent blood transfusion (if blood sample used)
- ●Bone marrow transplant (chimerism)
Compare With Similar Tests
| Test | PAX9 Gene Tooth agenesis, selective type 3 NGS Genetic Test | MSX1 Gene Sequencing | AXIN2 Gene Sequencing | Tooth Agenesis Panel (Multiple Genes) |
|---|---|---|---|---|
| Comparison | PAX9 Gene Tooth agenesis, selective type 3 NGS Genetic Test |
Frequently Asked Questions
What is the PAX9 gene tooth agenesis selective type 3 NGS genetic test?
What is the cost of the PAX9 gene NGS test at DNA Labs India?
What sample is required for this test?
Do I need to fast before the test?
How long does it take to get the results?
Will I receive raw data files?
Is home sample collection available?
What does a positive result mean?
Can this test detect all causes of tooth agenesis?
Is genetic counseling included?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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