Skip to main content
DNA Labs India

PCSK1 Gene Obesity with impaired prohormone processing NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

PCSK1 Gene Obesity with impaired prohormone processing NGS Genetic Test

PCSK1 Gene Obesity with impaired prohormone processing NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

Next-Generation Sequencing (NGS)🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To diagnose mutations in the PCSK1 gene causing obesity with impaired prohormone processing, aiding in clinical management and genetic counseling.

Test Code
2618
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Provide clinical history of the patient and undergo a genetic counseling session to draw a pedigree chart of affected family members.

Step 2

Laboratory Analysis

Blood sample collection or DNA extraction using specified methods.

Step 3

Report Delivery

Sample is sent for NGS analysis at the laboratory.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Provide clinical history and undergo genetic counseling as per pre-test information.
2
During the Test:Blood sample or DNA collection is performed.
3
After the Test:Sample undergoes NGS analysis, and reports are delivered in 3 to 4 weeks.

About This Test

Who Should Get This Test

To diagnose mutations in the PCSK1 gene causing obesity with impaired prohormone processing, aiding in clinical management and genetic counseling.

How to Prepare

  • Collect blood in appropriate anticoagulant tube
  • Alternatively, use extracted DNA or one drop blood on FTA card
  • Ensure proper labeling and transport at ambient room temperature

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card

Understanding Your Results

Results indicate the presence or absence of mutations in the PCSK1 gene associated with obesity and impaired prohormone processing.
📊

Positive

Pathogenic variant detected in PCSK1 gene, confirming diagnosis of PCSK1 deficiency.

📊

Negative

No pathogenic variants detected, suggesting absence of PCSK1 gene-related disorder.

📊

Variant of uncertain significance

Genetic variant identified but clinical significance is unclear; further testing or counseling may be needed.

⚠️ When to Consult a Doctor:

If symptoms such as early-onset obesity, increased appetite, or other related issues are present, or if there is a family history of similar conditions.

Risks & Considerations

  • ●Minimal risk associated with blood collection, such as bruising or infection

Frequently Asked Questions

What is PCSK1 Gene Obesity with Impaired Prohormone Processing?
It is a rare genetic disorder caused by mutations in the PCSK1 gene, leading to impaired hormone processing and obesity.
What are the common symptoms of this disorder?
Symptoms include early-onset obesity, increased appetite, delayed development, low blood sugar levels, impaired glucose tolerance, decreased muscle tone, and behavioral problems.
How is PCSK1 Gene Obesity diagnosed?
Diagnosis is through genetic testing, specifically NGS analysis of the PCSK1 gene to identify mutations.
What is the cost of the NGS Genetic Test at DNA Labs India?
The test costs INR 20,000, with free home sample collection available across India.
What sample types are accepted for this test?
Blood, extracted DNA, or one drop blood on FTA card are accepted.
Is fasting required before the test?
No, fasting is not required for this genetic test.
How long does it take to get the test results?
Reports are typically delivered in 3 to 4 weeks.
Why should I choose DNA Labs India for this test?
DNA Labs India offers accurate results, state-of-the-art technology, experienced genetic counselors, confidentiality, and fast turnaround times.
What is the purpose of genetic counseling before the test?
Genetic counseling helps understand the test implications, draw a family pedigree chart, and discuss potential outcomes.
Are there any risks associated with this test?
Risks are minimal, similar to any blood draw, such as slight bruising or infection at the collection site.
Can this test be done for children?
Yes, the test is suitable for all ages, especially if early-onset symptoms are present.
What should I do if the test results are positive?
Consult a healthcare provider or genetic counselor for further management, which may include lifestyle changes, monitoring, or other interventions.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

CYP21A2 Gene Adrenal hyperplasia due to 21-hydroxylase deficiency NGS Genetic Test

₹20,000

HSD17B3 Gene Pseudohermaphroditism with gynecomastia NGS Genetic Test

₹20,000

CYP27B1 Gene Rickets, vitamin D dependent, type 1 NGS Genetic Test

₹20,000

TBCE Gene Hypoparathyroidism-retardation-dysmorphism syndrome NGS Genetic Test

₹20,000

TSHR Gene Hypothyroidism congenital nongoitrous type 1 NGS Genetic Test

₹20,000

PAX8 Gene Hypothyroidism congenital nongoitrous type 2, familial NGS Genetic Test

₹20,000
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.