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DNA Labs India

POU3F4 Gene Deafness, X-linked type 2 NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

POU3F4 Gene Deafness, X-linked type 2 NGS Genetic Test

Also known as: X-linked deafness type 2, DFNX2

POU3F4 Gene Deafness, X-linked type 2 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic TestAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To detect mutations in the POU3F4 gene for definitive diagnosis of X-linked type 2 deafness, enabling early intervention, genetic counseling, and family planning.

Test Code
4761
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Provide detailed clinical and family history. Ensure proper identification and consent.

Method: Venipuncture

Step 2

Laboratory Analysis

Blood sample collection via venipuncture using sterile equipment.

Step 3

Report Delivery

Sample is labeled, stored appropriately, and sent to the lab for analysis.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Provide detailed clinical and family history. No fasting required.
2
During the Test:Blood sample collection via venipuncture.
3
After the Test:Sample processed for NGS analysis; results available in 3-4 weeks.

About This Test

Who Should Get This Test

To detect mutations in the POU3F4 gene for definitive diagnosis of X-linked type 2 deafness, enabling early intervention, genetic counseling, and family planning.

How to Prepare

  • Ensure proper patient identification
  • Use sterile collection equipment
  • Follow standard blood collection procedures
  • Label samples correctly

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"This test is crucial for early diagnosis and management of X-linked deafness, aiding in genetic counseling and family planning."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture

Sample Stability

Blood samples stable at room temperature for 24 hours
Extracted DNA stable at -20°C for long-term storage
Sample Rejection Criteria:
  • Hemolyzed samples
  • Insufficient sample volume
  • Improperly labeled or contaminated samples

Understanding Your Results

Results should be interpreted by a qualified geneticist or healthcare provider in the context of clinical findings and family history.
Positive: Pathogenic variant detected in POU3F4 gene, confirming diagnosis
Negative: No pathogenic variants detected, but clinical correlation is advised
Variant of uncertain significance: Further testing or family studies may be recommended
⚠️ When to Consult a Doctor:

If symptoms of hearing loss, balance issues, or vision problems are present, or if there is a family history of X-linked deafness, consult a geneticist or ENT specialist.

Limitations

  • ⚠Test only detects mutations in POU3F4 gene
  • ⚠May not detect all genetic causes of deafness
  • ⚠Results require genetic counseling interpretation

Risks & Considerations

  • ●Minor bruising at blood draw site
  • ●Rare risk of infection
  • ●Discomfort during blood collection

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA
  • ●Technical errors in sequencing

Frequently Asked Questions

What is the POU3F4 Gene Deafness, X-linked type 2 NGS Genetic Test?
It is a genetic test that uses next-generation sequencing to analyze the POU3F4 gene for mutations causing X-linked type 2 deafness.
How much does the test cost?
The test costs INR 20,000 at DNA Labs India, including sample collection and analysis.
What are the symptoms of POU3F4 Gene Deafness?
Symptoms include severe to profound hearing loss, balance problems, and in some cases, vision issues.
How is the test performed?
A blood sample is collected and analyzed using NGS technology to detect mutations in the POU3F4 gene.
What sample is required for the test?
Blood, extracted DNA, or one drop of blood on an FTA card.
How long does it take to get the results?
Results are typically available in 3 to 4 weeks.
Is the test accurate?
Yes, NGS technology provides high accuracy for detecting genetic mutations.
Who should get this test?
Individuals with hearing loss symptoms, family history of X-linked deafness, or for carrier testing.
Is home sample collection available?
Yes, free home sample collection is available for online bookings across India.
What does a positive result mean?
A positive result indicates a pathogenic variant in the POU3F4 gene, confirming the diagnosis.
What does a negative result mean?
A negative result means no pathogenic variants were detected, but clinical correlation is advised.
Are there any risks associated with the test?
Risks are minimal, including minor bruising or discomfort during blood draw.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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