PRKAR1A Gene Pigmented nodular adrenocortical disease type 1, primary NGS Genetic Test
Short Name: PRKAR1A Gene Test
Also known as: Pigmented Nodular Adrenocortical Disease Type 1, PNAD Type 1, Primary Pigmented Nodular Adrenocortical Disease
PRKAR1A Gene Pigmented nodular adrenocortical disease type 1, primary NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To diagnose Pigmented Nodular Adrenocortical Disease Type 1 by identifying mutations in the PRKAR1A gene, guide treatment and management strategies, and assess risk for family members.
- Test Code
- 5482
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No specific preparation required. Provide clinical history and family pedigree information.
Method: Venipuncture for blood samples
Laboratory Analysis
Blood sample collected via venipuncture or use of FTA card for one drop of blood.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Store sample as per instructions.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
To diagnose Pigmented Nodular Adrenocortical Disease Type 1 by identifying mutations in the PRKAR1A gene, guide treatment and management strategies, and assess risk for family members.
How to Prepare
- Ensure proper labeling of samples
- Use sterile collection tubes
- Transport samples at ambient room temperature
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This test is crucial for diagnosing rare genetic disorders affecting adrenal function, aiding in early intervention and family planning."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood samples
- Insufficient sample volume
- Improperly labeled samples
Understanding Your Results
No pathogenic variant detected
Negative for PRKAR1A gene mutations; clinical correlation recommended
Pathogenic variant detected
Positive for PRKAR1A gene mutation; confirms diagnosis and guides management
Consult a doctor if you have symptoms like high blood pressure, weight gain, or muscle weakness, or if you have a family history of adrenal disorders. After receiving test results, consult for personalized treatment plans.
Limitations
- ⚠May not detect all possible mutations in the PRKAR1A gene
- ⚠Requires genetic counseling for proper interpretation
- ⚠Results should be correlated with clinical findings
Risks & Considerations
- ●Minimal risks from blood draw, such as bruising or infection
- ●No significant risks associated with genetic testing itself
Interfering Factors
- ●Sample contamination
- ●Technical errors during sequencing
- ●Insufficient DNA quality
Compare With Similar Tests
| Test | PRKAR1A Gene Pigmented nodular adrenocortical disease type 1, primary NGS Genetic Test | ||||
|---|---|---|---|---|---|
| Comparison | PRKAR1A Gene Pigmented nodular adrenocortical disease type 1, primary NGS Genetic Test | Measures adrenal function but does not identify genetic mutations | Assesses hormone levels but not specific genetic causes | Visualizes adrenal nodules but cannot confirm genetic etiology | Tests for related disorders but targets different genes |
Frequently Asked Questions
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₹20,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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