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DNA Labs India

Pre-Operative Panel Test

DNA Labs India | ISO 9001:2015 Certified

Pre-Operative Panel Test

Short Name: PROC Test

Also known as: Procainamide Level Test, PROC Level Test, Procainamide and NAPA Test

Pre-Operative Panel Test test available at DNA Labs India for ₹18,000. Uses Immunoassay on Serum samples. Results in Reports available after 2-3 weeks from sample receipt.. Free home collection in 300+ cities across India.

Blood TestAdults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To monitor therapeutic levels of Procainamide and its active metabolite N-acetylprocainamide (NAPA) in patients undergoing treatment for atrial and ventricular arrhythmias, ensuring drug efficacy and preventing toxicity.

Test Code
1394
Price
₹18,000
Sample Type
Serum
Result Time
Reports available after 2-3 weeks from sample receipt.
Fasting Required
No
Method
Immunoassay
Step 1

Sample Collection

Specimen should be collected just before the next dose is due at steady state. A duly filled Test Send Out Consent Form (Form 35) is mandatory. No fasting required, but timing relative to dose is critical.

Method: Venipuncture

Step 2

Laboratory Analysis

Standard venipuncture procedure to collect 2 mL blood in a Red Top (no additive) tube.

Step 3

Report Delivery

Ship refrigerated. Do not freeze. Ensure sample stability: room temperature for 8 hours, refrigerator for 1 week.

Timeline: Reports available after 2-3 weeks from sample receipt.

Patient Instructions

1
Before the Test:Ensure specimen collection timing is just before the next dose at steady state. No fasting required.
2
During the Test:Blood draw from a vein in the arm, typically taking a few minutes.
3
After the Test:Apply pressure to the puncture site. Resume normal activities. Monitor for any bruising or discomfort.

About This Test

Who Should Get This Test

To monitor therapeutic levels of Procainamide and its active metabolite N-acetylprocainamide (NAPA) in patients undergoing treatment for atrial and ventricular arrhythmias, ensuring drug efficacy and preventing toxicity.

How to Prepare

  • Collect specimen just before next dose at steady state
  • Use Red Top (no additive) tube, avoid SST gel barrier tubes
  • Label tube with patient details
  • Ship refrigerated, not frozen
  • Submit consent form (Form 35) with sample

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Regular monitoring of Procainamide and NAPA levels is crucial to ensure therapeutic efficacy and avoid toxicity in patients with arrhythmias."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume2 mL (1 mL min.)
Container1 Red Top (No Additive) tube. Do not use SST gel barrier tubes.
Collection MethodVenipuncture

Sample Stability

Room Temperature: 8 hours
Refrigerator: 1 week
Frozen: Not acceptable
Sample Rejection Criteria:
  • Use of incorrect tube (e.g., SST gel barrier)
  • Hemolyzed or lipemic samples
  • Missing consent form
  • Sample not shipped refrigerated

Understanding Your Results

Procainamide and NAPA levels are interpreted together to assess drug status. Therapeutic ranges indicate effective treatment, while levels outside this range may indicate toxicity or subtherapeutic dosing.
📊

Therapeutic range; drug levels are within effective limits for arrhythmia control.

Range: Procainamide 4-10 µg/mL and NAPA 10-20 µg/mL

📊

Potential toxicity; risk of adverse effects like nausea, dizziness, or cardiac issues. Dose adjustment may be needed.

Range: Procainamide >10 µg/mL or NAPA >20 µg/mL

📊

Subtherapeutic levels; drug may be ineffective. Consider dose increase or compliance check.

Range: Procainamide <4 µg/mL or NAPA <10 µg/mL

⚠️ When to Consult a Doctor:

If you experience symptoms such as nausea, vomiting, headache, dizziness, blurred vision, confusion, seizures, low blood pressure, or irregular heartbeat while on Procainamide, consult your doctor immediately. Also, consult for dose adjustments based on test results.

Limitations

  • ⚠Measures total drug levels, not free or protein-bound fractions
  • ⚠Does not differentiate between parent drug and metabolite in terms of activity
  • ⚠Reference ranges may vary based on laboratory methods

Risks & Considerations

  • ●Minor bruising or pain at the blood draw site
  • ●Rare risk of infection or dizziness
  • ●No significant risks associated with the test itself

Interfering Factors

  • ●Use of SST gel barrier tubes may affect results
  • ●Hemolyzed or lipemic samples
  • ●Concurrent medications that alter Procainamide metabolism
  • ●Non-steady state sampling timing

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Frequently Asked Questions

What is the Procainamide test?
The Procainamide test measures the levels of Procainamide and its metabolite NAPA in the blood to monitor therapeutic drug levels for treating cardiac arrhythmias.
Why is the Procainamide test done?
It is done to ensure that Procainamide levels are within the therapeutic range to effectively manage arrhythmias while avoiding toxicity.
What is the cost of the Procainamide test at DNA Labs India?
The cost is INR 18,000, which includes home sample collection and reporting.
What sample is required for the test?
2 mL of blood from a Red Top (no additive) tube is required. SST gel barrier tubes should not be used.
Is fasting required for the Procainamide test?
No traditional fasting is required, but the specimen should be collected just before the next dose is due at steady state.
How long does it take to get the results?
Reports are typically available within 2-3 weeks after sample receipt.
What are normal levels for Procainamide and NAPA?
Therapeutic ranges are generally 4-10 µg/mL for Procainamide and 10-20 µg/mL for NAPA, but ranges may vary by lab.
What symptoms indicate Procainamide overdose?
Symptoms include nausea, vomiting, headache, dizziness, blurred vision, confusion, seizures, low blood pressure, and irregular heartbeat.
How is the test performed?
A blood sample is drawn from a vein in the arm and analyzed using immunoassay to measure drug levels.
Can this test be done at home?
Yes, DNA Labs India offers free home sample collection for online bookings across many cities in India.
What should I do if my levels are high?
Consult your doctor immediately for dose adjustment and monitoring to prevent toxicity.
Is the Procainamide test covered by insurance?
Coverage depends on your insurance policy and scheme; check with your provider for details.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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