RET Gene Hirschsprung disease NGS Genetic Test
Short Name: RET Gene Hirschsprung Disease NGS Test
Also known as: HSCR, Congenital Aganglionic Megacolon
RET Gene Hirschsprung disease NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
To identify mutations in the RET gene associated with Hirschsprung disease for accurate diagnosis, risk assessment, and personalized treatment planning.
- Test Code
- 5771
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Clinical history of the patient and a genetic counseling session to draw a pedigree chart of family members affected with Hirschsprung disease.
Laboratory Analysis
Your sample is analyzed using Next-Generation Sequencing (NGS) in our laboratory.
Report Delivery
A certified pathologist reviews and signs your report. You receive it as a secure PDF via email and WhatsApp.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
To identify mutations in the RET gene associated with Hirschsprung disease for accurate diagnosis, risk assessment, and personalized treatment planning.
How to Prepare
- Collect blood sample using standard venipuncture techniques.
- Alternatively, use extracted DNA or one drop of blood on an FTA card.
- Ensure proper labeling and handling of samples.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Understanding Your Results
Positive for pathogenic RET mutation
Confirms genetic basis for Hirschsprung disease; recommend clinical evaluation and family screening.
Negative for pathogenic RET mutation
No mutations detected; consider other diagnostic tests if symptoms persist.
Consult a doctor if symptoms like chronic constipation, abdominal distension, or failure to thrive are present, especially in infants or with a family history of Hirschsprung disease.
Risks & Considerations
- ●Minimal physical risk from blood draw.
- ●Potential psychological impact from genetic results.
- ●Risk of false positives or negatives, though rare with NGS.
Frequently Asked Questions
What is Hirschsprung disease?
What causes Hirschsprung disease?
What is the RET gene?
How is the NGS Genetic Test performed?
What is the cost of the RET Gene Hirschsprung Disease NGS Test?
Is home sample collection available?
How long does it take to get results?
What are the risks of the test?
Who should get tested for Hirschsprung disease?
How should I prepare for the test?
What if the test results are positive?
Is the test covered by insurance?
Related Tests
Amino Acids Qualitative Two Dimensional Urine Test
₹1,439Succinylacetone Urine Test
₹5,000RXFP2 Gene Cryptorchidism NGS Genetic Test
₹20,000EFNB1 Gene Craniofrontonasal syndrome NGS Genetic Test
₹20,000MNX1 Gene Currarino syndrome NGS Genetic Test
₹20,000FGFR1 Gene Craniosynostosis, FGFR1 related NGS Genetic Test
₹20,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.