RNA Extraction from Plasma or Serum Test
Short Name: RNA Extraction
Also known as: Plasma RNA Extraction, Serum RNA Extraction, Cell-free RNA Extraction
RNA Extraction from Plasma or Serum Test test available at DNA Labs India for ₹3,000. Uses RNA isolation, RT-PCR (if required) on Plasma or Serum samples. Results in Reports are typically delivered within 1 week after sample collection.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The primary purpose of RNA extraction from plasma or serum is to isolate high-quality RNA for downstream molecular analysis. This includes detecting viral RNA (e.g., HIV, hepatitis C, Zika), quantifying gene expression, identifying mutations associated with cancer, and monitoring disease progression or treatment response. By providing a pure RNA sample, this test enables accurate and sensitive detection of biomarkers, facilitating early diagnosis and personalized treatment strategies.
- Test Code
- 6415
- CPT Code
- CPT 83891
- ICD Code
- Z01.89
- Price
- ₹3,000
- Sample Type
- Plasma or Serum
- Result Time
- Reports are typically delivered within 1 week after sample collection.
- Fasting Required
- No
- Method
- RNA isolation, RT-PCR (if required)
Sample Collection
No special preparation is required. However, inform your healthcare provider about any medications or supplements you are taking.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm. The procedure is quick and minimally invasive.
Report Delivery
You may resume normal activities immediately. The sample will be processed in the laboratory.
Timeline: Reports are typically delivered within 1 week after sample collection.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of RNA extraction from plasma or serum is to isolate high-quality RNA for downstream molecular analysis. This includes detecting viral RNA (e.g., HIV, hepatitis C, Zika), quantifying gene expression, identifying mutations associated with cancer, and monitoring disease progression or treatment response. By providing a pure RNA sample, this test enables accurate and sensitive detection of biomarkers, facilitating early diagnosis and personalized treatment strategies.
How to Prepare
- Use EDTA tube for plasma or SST for serum
- Collect blood aseptically
- Label the tube with patient details
- Transport to laboratory within 2 hours at 2-8°C
- Avoid hemolysis
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"RNA extraction from plasma or serum is a critical step in molecular diagnostics, enabling the detection of viral RNA and gene expression biomarkers. Timely and accurate extraction ensures reliable downstream analysis, which is essential for early diagnosis and monitoring of diseases such as HIV, hepatitis, and certain cancers."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed sample
- Clotted sample (if plasma required)
- Improper labeling
- Sample received after prolonged delay
- Incorrect tube type
Understanding Your Results
Suitable for downstream analysis
Indicates successful extraction; proceed with molecular testing
May require re-extraction or alternative sample
Could affect sensitivity of downstream tests
Poor integrity
May lead to false-negative results; repeat sample recommended
Consult your healthcare provider if you have symptoms suggestive of viral infection, cancer, or if you are undergoing treatment that requires monitoring of RNA biomarkers. Early consultation can aid in timely diagnosis and management.
Limitations
- ⚠RNA is labile and requires careful handling
- ⚠Low RNA yield may occur in some samples
- ⚠Results depend on sample quality and timing
- ⚠Not a diagnostic test itself; requires downstream analysis
Risks & Considerations
- ●Minor bruising at the puncture site
- ●Dizziness or fainting (rare)
- ●Infection (very rare, aseptic techniques are used)
Interfering Factors
- ●Hemolysis can degrade RNA and affect results
- ●Improper sample storage or delayed processing
- ●Contamination with nucleases
- ●Presence of inhibitors in the sample
- ●Incorrect anticoagulant or tube type
Compare With Similar Tests
| Test | RNA Extraction from Plasma or Serum | DNA Extraction | Whole Blood RNA Extraction |
|---|---|---|---|
| Comparison | RNA Extraction from Plasma or Serum |
Frequently Asked Questions
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