SCNN1B Gene Liddle syndrome NGS Genetic Test
Short Name: SCNN1B Gene Liddle Syndrome Test
Also known as: Liddle Syndrome Genetic Test, SCNN1B Mutation Analysis, ENaC Gene Test
SCNN1B Gene Liddle syndrome NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the SCNN1B Gene Liddle Syndrome NGS Genetic Test is to identify pathogenic mutations in the SCNN1B gene that cause Liddle syndrome. This aids in accurate diagnosis, differentiation from other forms of hypertension, and guides personalized treatment plans to prevent complications such as cardiovascular damage.
- Test Code
- 2611
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- NGS Technology
Sample Collection
No specific preparation required. Provide clinical history and family pedigree during genetic counseling.
Method: Venipuncture or FTA Card
Laboratory Analysis
A blood sample will be drawn from a vein in the arm, or a drop of blood can be collected on an FTA card.
Report Delivery
Apply pressure to the puncture site to prevent bruising. Resume normal activities unless advised otherwise.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the SCNN1B Gene Liddle Syndrome NGS Genetic Test is to identify pathogenic mutations in the SCNN1B gene that cause Liddle syndrome. This aids in accurate diagnosis, differentiation from other forms of hypertension, and guides personalized treatment plans to prevent complications such as cardiovascular damage.
How to Prepare
- Ensure proper identification of the patient
- Use sterile equipment for blood draw
- Label samples correctly with patient details
- Store samples at ambient temperature if using FTA card
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This test is essential for diagnosing Liddle syndrome, a rare genetic disorder causing hypertension and hypokalemia, often misdiagnosed as essential hypertension."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood samples
- Insufficient sample volume
- Incorrect labeling or missing patient information
- Contaminated samples
Understanding Your Results
Pathogenic variant detected
Confirms diagnosis of Liddle syndrome. Recommend genetic counseling and targeted treatment.
Likely pathogenic variant detected
Strong indication of Liddle syndrome. Clinical correlation and family testing advised.
Variant of uncertain significance (VUS)
Uncertain clinical significance. Repeat testing or functional studies may be needed.
No pathogenic variant detected
Liddle syndrome unlikely based on this gene. Consider other genetic or non-genetic causes.
Consult a doctor if you have symptoms like hypertension, hypokalemia, or a family history of Liddle syndrome. After testing, discuss results with a geneticist or nephrologist for management.
Limitations
- ⚠May not detect all types of mutations, such as large deletions or duplications
- ⚠Results require interpretation by a geneticist or healthcare provider
- ⚠Does not rule out other genetic causes of hypertension
- ⚠Genetic counseling is essential for understanding results
Risks & Considerations
- ●Minor bruising or pain at the blood draw site
- ●Rare risk of infection
- ●Fainting or dizziness during blood collection
Interfering Factors
- ●Poor sample quality or degradation
- ●Contamination during sample collection or processing
- ●Recent blood transfusion may affect DNA analysis
- ●Inadequate sample volume
Frequently Asked Questions
What is Liddle syndrome?
What are the symptoms of Liddle syndrome?
How is Liddle syndrome diagnosed?
What is the cost of the SCNN1B Gene Liddle Syndrome NGS Genetic Test in India?
What sample is required for this test?
Is fasting required before the test?
How long does it take to get results?
Is home sample collection available?
What should I do if I test positive for Liddle syndrome?
Can this test be done for children?
What is the accuracy of the NGS Genetic Test?
Are there any risks associated with the test?
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₹20,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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