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SECISBP2 Gene Thyroid hormone metabolism abnormal NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

SECISBP2 Gene Thyroid hormone metabolism abnormal NGS Genetic Test

Short Name: SECISBP2 Gene Test

Also known as: SECISBP2 Gene Mutation Test, Thyroid Hormone Metabolism Genetic Test

SECISBP2 Gene Thyroid hormone metabolism abnormal NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3-4 weeks. Free home collection in 300+ cities across India.

Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SHAILAJA RAGHUNATH MURDESHWAR

Dr SHAILAJA RAGHUNATH MURDESHWAR

Consultant Physician · Reg: 8052

Last reviewed: September 7, 2026

Overview

To identify mutations in the SECISBP2 gene that cause thyroid hormone metabolism abnormalities, aiding in diagnosis and management of related disorders.

Test Code
2654
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3-4 weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Provide clinical history and undergo genetic counseling to draw a pedigree chart of family members affected with thyroid disorders.

Method: Venipuncture or FTA card collection

Step 2

Laboratory Analysis

Blood sample collection via venipuncture or FTA card.

Step 3

Report Delivery

Sample sent to laboratory for NGS analysis.

Timeline: 3-4 weeks

Patient Instructions

1
Before the Test:Genetic counseling and clinical history review.
2
During the Test:Sample collection and processing for NGS analysis.
3
After the Test:Report generation and consultation with healthcare provider.

About This Test

Who Should Get This Test

To identify mutations in the SECISBP2 gene that cause thyroid hormone metabolism abnormalities, aiding in diagnosis and management of related disorders.

How to Prepare

  • Ensure proper sample collection
  • Label sample correctly with patient details

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"This test is crucial for diagnosing genetic causes of thyroid disorders and guiding personalized treatment plans."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume5 mL blood or equivalent
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or FTA card collection

Sample Stability

Blood: 24 hours at room temperature
FTA card: Stable at room temperature for extended periods
Sample Rejection Criteria:
  • Hemolyzed sample
  • Insufficient sample volume
  • Improper labeling

Understanding Your Results

Results indicate the presence or absence of mutations in the SECISBP2 gene related to thyroid hormone metabolism abnormalities.
📊

Positive for mutation

Genetic cause of thyroid disorder likely; consult a specialist for management.

📊

Negative for mutation

No genetic mutation detected in SECISBP2 gene; consider other causes of symptoms.

⚠️ When to Consult a Doctor:

If symptoms of thyroid abnormalities persist, family history of thyroid disorders, or if genetic testing is recommended by a healthcare provider.

Limitations

  • ⚠May not detect all mutations
  • ⚠Requires genetic counseling for interpretation

Risks & Considerations

  • ●Minimal risk from blood draw
  • ●Genetic privacy concerns

Interfering Factors

  • ●Contaminated DNA sample
  • ●Improper sample collection

Frequently Asked Questions

What is the SECISBP2 gene?
The SECISBP2 gene encodes a protein essential for selenoprotein synthesis, which is crucial for thyroid hormone metabolism.
What are thyroid hormone metabolism abnormalities?
These are conditions where there is an imbalance in thyroid hormone production and utilization, leading to symptoms like fatigue and weight gain.
How is the SECISBP2 Gene NGS Genetic Test performed?
The test uses Next-Generation Sequencing to analyze DNA from blood or saliva samples for mutations in the SECISBP2 gene.
What is the cost of this test?
The test costs INR 20000 at DNA Labs India, with free home sample collection available across India.
Who should consider this test?
Individuals with symptoms of thyroid disorders, family history of thyroid abnormalities, or unexplained hypothyroidism.
What symptoms indicate the need for this test?
Symptoms include fatigue, weight gain, depression, hair loss, goiter, dry skin, and constipation.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for this test in numerous cities across India.
What is NGS technology?
Next-Generation Sequencing is an advanced genetic testing method that allows for rapid and accurate sequencing of DNA to detect mutations.
Can this test diagnose all thyroid disorders?
No, it specifically detects mutations in the SECISBP2 gene related to thyroid hormone metabolism abnormalities.
Is genetic counseling required before the test?
Yes, a genetic counseling session is recommended to understand the test implications and draw a family pedigree chart.
What if the test result is positive?
A positive result indicates a genetic mutation; consult a doctor for further management, which may include treatment and monitoring.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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