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SFTPA2 Gene Pulmonary fibrosis, idiopathic NGS Genetic Test

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SFTPA2 Gene Pulmonary fibrosis, idiopathic NGS Genetic Test

Short Name: SFTPA2 Gene Pulmonary Fibrosis NGS Test

Also known as: SFTPA2 Mutation Test, Surfactant Protein A2 Gene Test, Pulmonary Fibrosis Genetic Test

SFTPA2 Gene Pulmonary fibrosis, idiopathic NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify mutations in the SFTPA2 gene associated with idiopathic pulmonary fibrosis, enabling accurate diagnosis, genetic counseling, and personalized treatment planning.

Test Code
4793
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Inform the lab about any medications or health conditions. Genetic counseling recommended prior to testing.

Method: Venipuncture or FTA card spot

Step 2

Laboratory Analysis

Blood sample will be drawn by a trained phlebotomist. For FTA card, a drop of blood is applied to the card.

Step 3

Report Delivery

Apply pressure to the puncture site to stop bleeding. Sample will be processed for DNA extraction and NGS analysis.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Genetic counseling session to discuss family history, test implications, and informed consent.
2
During the Test:Sample collection via blood draw or FTA card, followed by DNA extraction and NGS analysis in the lab.
3
After the Test:Report generation within 3-4 weeks, with genetic counseling for result interpretation and guidance.

About This Test

Who Should Get This Test

To identify mutations in the SFTPA2 gene associated with idiopathic pulmonary fibrosis, enabling accurate diagnosis, genetic counseling, and personalized treatment planning.

How to Prepare

  • Bring identification and doctor's prescription
  • Wear loose clothing for easy blood draw
  • Follow any specific instructions from the lab

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"This test is crucial for identifying genetic predisposition to pulmonary fibrosis, allowing for early intervention and personalized treatment plans."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume5-10 ml blood
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or FTA card spot

Sample Stability

Room temperature
Sample Rejection Criteria:
  • Insufficient sample volume
  • Hemolyzed sample
  • Incorrect sample type or container

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the SFTPA2 gene. Consult a geneticist or pulmonologist for detailed interpretation and next steps.
📊

Positive for pathogenic variant

Increased risk of pulmonary fibrosis; recommend clinical evaluation, monitoring, and family screening

📊

Negative for pathogenic variant

No SFTPA2 mutation detected; other genetic or environmental factors may be involved

📊

Variant of uncertain significance

Further testing, family studies, and clinical correlation recommended

⚠️ When to Consult a Doctor:

If you experience symptoms of pulmonary fibrosis, have a family history of the condition, or receive a positive genetic test result, consult a pulmonologist or geneticist promptly.

Limitations

  • ⚠May not detect all genetic variants
  • ⚠Results require clinical correlation
  • ⚠Not a standalone diagnostic tool

Risks & Considerations

  • ●Minimal risk from blood draw: bruising, infection, or discomfort
  • ●Psychological impact of genetic results, such as anxiety

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA quality

Frequently Asked Questions

What is the SFTPA2 gene and its role in pulmonary fibrosis?
The SFTPA2 gene encodes surfactant protein A, essential for lung immune function. Mutations can lead to abnormal protein production, causing lung damage and idiopathic pulmonary fibrosis.
How is the SFTPA2 gene NGS genetic test performed?
The test uses Next-Generation Sequencing (NGS) to analyze DNA from a blood or FTA card sample, detecting mutations in the SFTPA2 gene.
What is the cost of the SFTPA2 gene test in India?
The cost is INR 20000, which includes sample collection, NGS analysis, and genetic counseling report.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection for online bookings across numerous cities in India.
How long does it take to get the test results?
Results are typically available within 3 to 4 weeks after sample collection.
What are the common symptoms of pulmonary fibrosis?
Symptoms include shortness of breath during physical activity, persistent dry cough, fatigue, chest discomfort, and unexplained weight loss.
Can this test detect other genetic causes of pulmonary fibrosis?
This test specifically targets the SFTPA2 gene. For other genetic causes, additional tests like SFTPB or SFTPC gene tests may be recommended.
Is genetic counseling included with the test?
Yes, genetic counseling is included to help interpret results and discuss implications for you and your family.
What should I do if the test result is positive?
Consult a pulmonologist or geneticist for further evaluation, monitoring, and personalized treatment options.
Are there any risks associated with the genetic test?
Risks are minimal, primarily related to blood draw (e.g., bruising). Psychological impact of results is also possible.
How accurate is the NGS genetic test for SFTPA2 mutations?
NGS is highly accurate for detecting known mutations, but may not identify all variants. Results should be correlated with clinical findings.
Can children or infants undergo this test?
Yes, the test can be performed on individuals of all ages, but genetic counseling is recommended for minors.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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