Skip to main content
DNA Labs India

SFTPC Gene Surfactant metabolism dysfunction type 2 NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

SFTPC Gene Surfactant metabolism dysfunction type 2 NGS Genetic Test

Short Name: SFTPC Gene Test

Also known as: Surfactant Protein C Deficiency, SFTPC Mutation Test

SFTPC Gene Surfactant metabolism dysfunction type 2 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic TestAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SHAILAJA RAGHUNATH MURDESHWAR

Dr SHAILAJA RAGHUNATH MURDESHWAR

Consultant Physician · Reg: 8052

Last reviewed: September 7, 2026

Overview

To identify mutations in the SFTPC gene that cause surfactant metabolism dysfunction type 2, aiding in diagnosis, prognosis, and genetic counseling.

Test Code
2258
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Ensure no recent blood transfusions or bone marrow transplants. Provide clinical history and family pedigree.

Method: Venipuncture for blood sample

Step 2

Laboratory Analysis

Blood sample will be drawn by a trained phlebotomist. For FTA card, a small drop of blood is applied.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising. Sample will be sent to the lab for analysis.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Genetic counseling session to discuss test implications and draw family pedigree.
2
During the Test:DNA extraction and NGS analysis of the SFTPC gene.
3
After the Test:Review results with a geneticist and discuss next steps.

About This Test

Who Should Get This Test

To identify mutations in the SFTPC gene that cause surfactant metabolism dysfunction type 2, aiding in diagnosis, prognosis, and genetic counseling.

How to Prepare

  • Use sterile techniques
  • Label samples correctly
  • Transport at ambient temperature

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"Early genetic testing for SFTPC mutations can guide treatment and family planning for surfactant metabolism dysfunction."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture for blood sample

Sample Stability

Blood samples stable for 48 hours at room temperature
Extracted DNA stable for longer periods
Sample Rejection Criteria:
  • Hemolyzed samples
  • Insufficient sample volume
  • Improper labeling
  • Contaminated samples

Understanding Your Results

Results indicate the presence or absence of pathogenic SFTPC gene mutations. Positive results confirm diagnosis, while negative results may require further testing.
📊

Confirms surfactant metabolism dysfunction type 2. Consult genetic counselor for management.

📊

No pathogenic mutations detected. Consider other causes if symptoms persist.

📊

Mutation detected but significance unknown. Requires further clinical and family studies.

⚠️ When to Consult a Doctor:

If you experience symptoms like chronic cough, breathing difficulties, or have a family history of lung disorders, consult a healthcare provider for genetic testing.

Limitations

  • ⚠May not detect all possible mutations
  • ⚠Variants of uncertain significance require clinical correlation
  • ⚠Does not assess other genes involved in lung surfactant disorders

Risks & Considerations

  • ●Minor bruising or pain at blood draw site
  • ●Very low risk of infection

Interfering Factors

  • ●Hemolyzed or degraded DNA samples
  • ●Contamination during sample collection
  • ●Incorrect sample type or volume

Frequently Asked Questions

What is the SFTPC Gene Surfactant Metabolism Dysfunction Type 2 NGS Genetic Test?
It is a genetic test that uses Next-Generation Sequencing to detect mutations in the SFTPC gene, which causes surfactant metabolism dysfunction type 2, a rare lung disorder.
What is the cost of the test in India?
The cost is INR 20,000, which includes sample collection and analysis. Discounts may be available for online bookings.
How is the test performed?
A blood sample or DNA is collected and analyzed using NGS technology to identify mutations in the SFTPC gene.
What sample is required for the test?
Blood, extracted DNA, or one drop of blood on an FTA card can be used.
Is fasting required for the test?
No, fasting is not required for this genetic test.
How long does it take to get the results?
Results are typically available within 3 to 4 weeks after sample collection.
Is home collection available for this test?
Yes, free home sample collection is available for online bookings across many cities in India.
What does a positive result mean?
A positive result confirms the presence of pathogenic SFTPC gene mutations, indicating surfactant metabolism dysfunction type 2. Consult a genetic counselor for management.
What should I do if the test is negative but symptoms persist?
Consult your healthcare provider for further evaluation, as other genetic or non-genetic conditions may be causing the symptoms.
Is the test covered by insurance?
Insurance coverage varies. Check with your provider; government schemes like PMJAY or CGHS may not cover it.
Can this test be used for prenatal diagnosis?
It can be used for prenatal diagnosis if there is a known family history, but genetic counseling is recommended first.
How accurate is the NGS genetic test?
NGS is highly accurate for detecting mutations, but it may not identify all variants. Clinical correlation is essential.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

Amino Acids Qualitative Urine & Plasma Test

₹3,000

Galactose Quantitative Plasma Test

₹1,872

Galactosemia Panel 3 Test

₹4,563

Galactosemia Panel 1 Test

₹2,867

Canavan Disease Test

₹4,500

Galactose-1-Phosphate Quantitative Blood Test

₹1,989
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.