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SOD2 Gene Microvascular complications of diabetes type 6, susceptibility to NGS Genetic Test

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SOD2 Gene Microvascular complications of diabetes type 6, susceptibility to NGS Genetic Test

Short Name: SOD2 Gene Test

Also known as: SOD2 polymorphism test, Diabetes microvascular risk genetic test

SOD2 Gene Microvascular complications of diabetes type 6, susceptibility to NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic TestAdults🏠 Home Collection

🩺 Medically Reviewed By

Overview

To identify mutations in the SOD2 gene that increase susceptibility to microvascular complications of diabetes, such as retinopathy, neuropathy, and nephropathy, enabling early intervention and personalized management.

Test Code
2171
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

No special preparation required. A genetic counseling session is recommended to discuss family history and draw a pedigree chart. Provide clinical history of the patient.

Method: Venipuncture or fingerstick

Step 2

Laboratory Analysis

Blood sample drawn via venipuncture or saliva collected non-invasively. For FTA card, one drop of blood is applied.

Step 3

Report Delivery

Sample is transported to the laboratory at ambient temperature for NGS analysis. Results are typically available in 3-4 weeks.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Undergo genetic counseling to understand implications. Provide informed consent and family medical history.
2
During the Test:Non-invasive sample collection (blood or saliva). Minimal discomfort, similar to routine blood draw.
3
After the Test:Await results in 3-4 weeks. Discuss findings with a healthcare provider for next steps.

About This Test

Who Should Get This Test

To identify mutations in the SOD2 gene that increase susceptibility to microvascular complications of diabetes, such as retinopathy, neuropathy, and nephropathy, enabling early intervention and personalized management.

How to Prepare

  • Use sterile collection kits provided by DNA Labs India
  • Label samples accurately with patient details
  • Ensure proper storage and transport at room temperature
  • Follow standard phlebotomy procedures for blood collection

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for SOD2 mutations can guide early intervention and personalized management to reduce the risk of severe diabetes complications."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume3-5 mL blood or equivalent
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or fingerstick

Sample Stability

Room temperature (15-25°C)Up to 7 days for blood samples; longer for DNA extracts
Sample Rejection Criteria:
  • Hemolyzed or clotted blood samples
  • Insufficient sample volume
  • Unlabeled or mislabeled samples
  • Contaminated samples

Understanding Your Results

Results from the SOD2 Gene NGS test indicate genetic susceptibility to microvascular complications of diabetes based on identified variants. Interpretation should be done in conjunction with clinical evaluation.
📊

No increased genetic risk for microvascular complications; maintain standard diabetes care.

📊

Increased susceptibility to complications; recommend enhanced monitoring, lifestyle modifications, and possible preventive therapies.

📊

Further testing or clinical correlation needed; genetic counseling advised.

⚠️ When to Consult a Doctor:

Consult a geneticist, endocrinologist, or healthcare provider if you have diabetes, a family history of complications, or if test results indicate increased risk, to discuss personalized management plans.

Limitations

  • Cannot predict exact timing or severity of complications
  • Does not replace regular clinical monitoring
  • Genetic risk may be influenced by other factors like lifestyle

Risks & Considerations

  • Minimal physical risk from blood draw (e.g., bruising, infection)
  • Potential psychological impact of genetic risk information
  • False sense of security if results are negative; risk still exists from other factors

Interfering Factors

  • Poor sample quality or contamination
  • Insufficient DNA yield
  • Sample degradation

Compare With Similar Tests

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ComparisonSOD2 Gene Microvascular complications of diabetes type 6, susceptibility to NGS Genetic Test

Frequently Asked Questions

What is the SOD2 gene?
The SOD2 gene encodes the superoxide dismutase 2 enzyme, which protects cells from oxidative stress caused by reactive oxygen species, playing a key role in cellular defense.
What are microvascular complications of diabetes?
These are complications affecting small blood vessels, including diabetic retinopathy (eye disease), neuropathy (nerve damage), and nephropathy (kidney disease), common in long-term diabetes.
How is this genetic test performed?
The test uses next-generation sequencing (NGS) to analyze the SOD2 gene from a blood or saliva sample, identifying mutations that may increase risk for diabetes complications.
Who should consider getting this test?
Individuals with diabetes, a family history of diabetes complications, or symptoms of microvascular issues may benefit from assessing genetic susceptibility.
What does a positive result mean?
A positive result indicates mutations in the SOD2 gene that may increase risk for microvascular complications; it does not mean you will definitely develop them but suggests need for closer monitoring.
Is there a cure for SOD2 gene mutations?
There is no cure for genetic mutations, but awareness can lead to preventive measures such as stricter blood sugar control, lifestyle changes, and regular screenings to manage risk.
How accurate is the NGS test?
NGS is highly accurate for detecting genetic variants, but results should be interpreted in clinical context by a geneticist or healthcare provider.
What is the cost of the test?
The cost is INR 20,000, which includes sample collection, analysis, genetic counseling, and a detailed report with raw data files.
How long does it take to get results?
Results are typically available in 3 to 4 weeks after sample collection, delivered via online portal, email, or WhatsApp.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection across many cities in India for online bookings, with no additional charge.
Can this test prevent diabetes complications?
While the test itself doesn't prevent complications, it provides information to guide personalized prevention strategies, potentially reducing risk through early intervention.
What should I do after receiving results?
Discuss results with a genetic counselor or doctor to understand implications, create a management plan, and consider further testing if needed.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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