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TAB2 Gene Congenital heart defects multiple types NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

TAB2 Gene Congenital heart defects multiple types NGS Genetic Test

Short Name: TAB2 CHD NGS Test

Also known as: TAB2 Gene Test, Congenital Heart Defect Genetic Test, TAB2 NGS Test

TAB2 Gene Congenital heart defects multiple types NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To detect mutations in the TAB2 gene associated with congenital heart defects, facilitating early diagnosis, risk assessment, and informed clinical decision-making.

Test Code
5248
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Clinical history of the patient and a genetic counseling session to draw a pedigree chart of family members affected with congenital heart defects. No fasting required.

Method: Venipuncture

Step 2

Laboratory Analysis

Standard venipuncture procedure to collect blood sample or use of FTA card for one drop of blood.

Step 3

Report Delivery

Sample labeled and transported to the lab under controlled conditions for DNA extraction and NGS analysis.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling session to discuss test implications, family history review, and informed consent.
2
During the Test:Blood sample collection and DNA extraction followed by NGS sequencing in the laboratory.
3
After the Test:Report generation with variant analysis, followed by genetic counseling to discuss results.

About This Test

Who Should Get This Test

To detect mutations in the TAB2 gene associated with congenital heart defects, facilitating early diagnosis, risk assessment, and informed clinical decision-making.

How to Prepare

  • Ensure patient identification and consent
  • Use sterile equipment for blood collection
  • Store sample at appropriate temperature
  • Transport to lab within 24 hours

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early genetic testing for TAB2 gene mutations can facilitate timely diagnosis and management of congenital heart defects, improving patient outcomes."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume3-5 mL blood
ContainerEDTA tube or FTA card
Collection MethodVenipuncture

Sample Stability

Blood samples: stable for 48 hours at 2-8°C
FTA cards: stable at room temperature for extended periods
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Insufficient sample volume
  • Improper labeling or documentation
  • Contaminated samples

Understanding Your Results

Results indicate the presence or absence of pathogenic variants in the TAB2 gene. Interpretation should be done by a genetic specialist in conjunction with clinical data.
📊

No pathogenic variants detected

Low genetic risk for TAB2-related congenital heart defects; clinical correlation recommended.

📊

Pathogenic variant detected

High genetic risk; further cardiac evaluation and genetic counseling advised.

📊

Variant of uncertain significance (VUS)

Requires additional family studies and clinical follow-up for clarification.

⚠️ When to Consult a Doctor:

Consult a cardiologist or genetic specialist if symptoms of congenital heart defects are present, family history is positive, or test results indicate pathogenic variants.

Limitations

  • ⚠May not detect all genetic variants or non-coding region mutations
  • ⚠Results require correlation with clinical findings and family history
  • ⚠Limited to known mutations in the TAB2 gene; novel variants may be classified as VUS
  • ⚠Does not replace comprehensive cardiac evaluation

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or infection
  • ●Psychological impact of genetic results
  • ●Potential for inconclusive results requiring further testing

Interfering Factors

  • ●Sample contamination during collection or processing
  • ●Degraded DNA due to improper storage
  • ●Hemolyzed blood samples
  • ●Recent blood transfusions affecting DNA analysis

Compare With Similar Tests

TestTAB2 Gene Congenital heart defects multiple types NGS Genetic TestNKX2-5 Gene CHD NGS TestGATA4 Gene CHD NGS TestTBX5 Gene CHD NGS TestComprehensive CHD Panel NGS Test
ComparisonTAB2 Gene Congenital heart defects multiple types NGS Genetic Test

Frequently Asked Questions

What is the TAB2 Gene Congenital Heart Defects NGS Genetic Test?
It is a Next-Generation Sequencing test that analyzes the TAB2 gene for mutations linked to various congenital heart defects.
Who should consider this test?
Individuals with a family history of congenital heart defects, symptoms like cyanosis or rapid breathing, or those diagnosed with CHDs such as VSDs or ASDs.
What is the cost of the test?
The test costs INR 20000.0, with free home sample collection available across India.
How is the sample collected?
A blood sample is collected via venipuncture, or one drop of blood can be used on an FTA card.
Is fasting required before the test?
No, fasting is not required for this genetic test.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
What do the results indicate?
Results show whether pathogenic variants in the TAB2 gene are detected, which can indicate genetic risk for congenital heart defects.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for this test in numerous cities across India.
What are the limitations of the test?
The test may not detect all genetic variants, and results should be correlated with clinical findings and family history.
Can this test diagnose all types of congenital heart defects?
It specifically tests for TAB2 gene mutations linked to certain CHDs; a comprehensive cardiac evaluation is recommended for full diagnosis.
Is genetic counseling provided?
Yes, a genetic counseling session is recommended before and after the test to discuss implications and results.
How accurate is the NGS Genetic Test?
NGS technology is highly accurate for detecting known mutations, but interpretation requires expert analysis and clinical correlation.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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