Skip to main content
DNA Labs India

TFR2 Gene Hemochromatosis type 3 NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

TFR2 Gene Hemochromatosis type 3 NGS Genetic Test

Short Name: TFR2 Hemochromatosis NGS Test

Also known as: Hereditary hemochromatosis type 3, TFR2-related iron overload disorder

TFR2 Gene Hemochromatosis type 3 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Results available in 3 to 4 weeks after sample collection.. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of the TFR2 Gene Hemochromatosis Type 3 NGS Genetic Test is to detect mutations in the TFR2 gene that cause hemochromatosis type 3, enabling early diagnosis, risk assessment, and management of iron overload disorders. It aids in identifying affected individuals and carriers, guiding treatment decisions, and facilitating family planning through genetic counseling.

Test Code
2067
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
Results available in 3 to 4 weeks after sample collection.
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Ensure genetic counseling session is completed. Provide clinical history and family pedigree chart. No fasting required.

Method: Venipuncture or fingerstick

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or one drop on FTA card. Procedure takes a few minutes with minimal discomfort.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising. Resume normal activities immediately.

Timeline: Results available in 3 to 4 weeks after sample collection.

Patient Instructions

1
Before the Test:Complete genetic counseling and provide clinical history. No special preparation needed.
2
During the Test:Blood sample collected via venipuncture or FTA card. Quick and minimally invasive.
3
After the Test:Apply bandage, monitor for any discomfort. Await results in 3-4 weeks.

About This Test

Who Should Get This Test

The purpose of the TFR2 Gene Hemochromatosis Type 3 NGS Genetic Test is to detect mutations in the TFR2 gene that cause hemochromatosis type 3, enabling early diagnosis, risk assessment, and management of iron overload disorders. It aids in identifying affected individuals and carriers, guiding treatment decisions, and facilitating family planning through genetic counseling.

How to Prepare

  • Schedule an appointment or opt for home collection
  • Bring identification and prescription if available
  • Inform staff of any medications or recent transfusions
  • Keep sample at ambient temperature until processed

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"As an obstetrician-gynecologist, I recommend this genetic test for individuals with a family history of iron disorders or symptoms like fatigue and joint pain, especially in reproductive planning to assess hereditary risks."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume5 mL blood or appropriate DNA volume
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or fingerstick

Sample Stability

Blood sample stable at room temperature for 24 hours
Extracted DNA stable at 2-8°C for up to 7 days
FTA card samples stable at room temperature for long-term storage
Sample Rejection Criteria:
  • Insufficient sample volume
  • Hemolyzed or clotted blood sample
  • Improper labeling or container leakage
  • Sample collected in incorrect tube type

Understanding Your Results

Results from the TFR2 Gene Hemochromatosis Type 3 NGS Genetic Test indicate the presence or absence of mutations in the TFR2 gene. A positive result suggests a genetic predisposition to hemochromatosis type 3, while a negative result reduces the likelihood but does not rule out other causes of iron overload.
Positive result: Pathogenic variant detected. Consult a geneticist for confirmatory testing and management plan.
Negative result: No pathogenic variant detected. Consider other diagnostic tests if symptoms persist.
Variant of uncertain significance: Further testing and family studies may be needed.
Carrier status: Individual carries one mutation; may be at risk of passing to offspring.
⚠️ When to Consult a Doctor:

Consult a doctor immediately if you experience symptoms of iron overload, have a family history of hemochromatosis, or receive a positive genetic test result. Regular follow-up is advised for monitoring and treatment.

Limitations

  • ⚠May not detect all possible variants in the TFR2 gene
  • ⚠Results require interpretation by a geneticist or healthcare provider
  • ⚠Does not replace clinical evaluation and other diagnostic tests
  • ⚠Genetic counseling is essential for understanding implications

Risks & Considerations

  • ●Minor bruising or pain at the blood draw site
  • ●Rare risk of infection or hematoma
  • ●Psychological impact of genetic results; counseling recommended

Interfering Factors

  • ●Contaminated or degraded DNA sample
  • ●Hemolyzed blood sample
  • ●Recent blood transfusion may affect DNA analysis
  • ●Technical errors in sample collection or processing

Compare With Similar Tests

TestTFR2 Gene Hemochromatosis type 3 NGS Genetic TestHFE Gene Mutation TestSerum Iron TestFerritin Test
ComparisonTFR2 Gene Hemochromatosis type 3 NGS Genetic Test

Frequently Asked Questions

What is the TFR2 Gene Hemochromatosis Type 3 NGS Genetic Test?
It is a genetic test that uses next-generation sequencing to detect mutations in the TFR2 gene, which cause hemochromatosis type 3, a disorder of iron overload.
Why should I get this test?
If you have a family history of hemochromatosis, symptoms like joint pain or fatigue, or elevated iron levels, this test can confirm genetic diagnosis and guide treatment.
What sample is required for the test?
A blood sample, extracted DNA, or one drop of blood on an FTA card can be used.
Is fasting required before the test?
No, fasting is not required for this genetic test.
How long does it take to get results?
Results are typically available in 3 to 4 weeks after sample collection.
What does a positive result mean?
A positive result indicates the presence of a pathogenic mutation in the TFR2 gene, increasing the risk for hemochromatosis type 3. Genetic counseling is recommended.
Is the test accurate?
Yes, NGS technology provides high accuracy in detecting mutations, but genetic counseling is essential for interpretation.
What is the cost of the test?
The test costs INR 20000, which includes sample collection and analysis.
Is home sample collection available?
Yes, free home collection is offered for online bookings across India.
Can this test be done for children?
Yes, it can be performed on individuals of all ages, but genetic counseling is advised for minors.
How is hemochromatosis type 3 treated?
Treatment may include regular phlebotomy to reduce iron levels, dietary changes, and monitoring for organ damage, guided by a healthcare provider.
What are the risks of this test?
Risks are minimal, such as bruising from blood draw. Psychological impact of results is possible; counseling can help.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

Amino Acids Qualitative Urine & Plasma Test

₹3,000

Galactose Quantitative Plasma Test

₹1,872

Galactosemia Panel 3 Test

₹4,563

Galactosemia Panel 1 Test

₹2,867

Canavan Disease Test

₹4,500

Galactose-1-Phosphate Quantitative Blood Test

₹1,989
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.